Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Runze Shang"'
Autor:
Hongwei Xu, Kefei Chen, Runze Shang, Xinyan Chen, Yi Zhang, Xinhua Song, Matthias Evert, Sheng Zhong, Bo Li, Diego F. Calvisi, Xin Chen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-11 (2021)
Abstract Hepatocellular carcinoma (HCC) is the sixth most common primary cancer with an unsatisfactory long-term survival. Gain of function mutations of PIK3CA occur in a subset of human HCC. Alpelisib, a selective PIK3CA inhibitor, has been approved
Externí odkaz:
https://doaj.org/article/26ba8f3f76ef4440b6b6c410f6f316c5
Autor:
Jianshe Shi, Chuheng Huang, Jialong Zheng, Yeqing Ai, Hiufang Liu, Zhiqiang Pan, Jiahai Chen, Runze Shang, Xinya Zhang, Shaoliang Dong, Rongkai Lin, Shurun Huang, Jianlong Huang, Chenghua Zhang
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundSeverely burned children are at high risk of secondary intraabdominal hypertension and abdominal compartment syndrome (ACS). ACS is a life-threatening condition with high mortality and requires an effective, minimally invasive treatment to
Externí odkaz:
https://doaj.org/article/eedcdc5bfd9043d08865caa42487e7b7
Autor:
Runze Shang, Miao Wang, Bin Dai, Jianbing Du, Jianlin Wang, Zekun Liu, Shibin Qu, Xisheng Yang, Jingjing Liu, Congcong Xia, Lin Wang, Desheng Wang, Yu Li
Publikováno v:
Molecular Oncology, Vol 14, Iss 6, Pp 1381-1396 (2020)
Hepatocellular carcinoma (HCC) is one of the most lethal malignant diseases worldwide. Despite advances in the diagnosis and treatment of HCC, its overall prognosis remains poor. Recent studies have shown that long noncoding RNAs (lncRNAs) play cruci
Externí odkaz:
https://doaj.org/article/9e238e384f2546248960d9d247b4fc29
Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma
Autor:
Bin Dai, Xuan Zhang, Runze Shang, Jianlin Wang, Xisheng Yang, Hong Zhang, Qi Liu, Desheng Wang, Lin Wang, Kefeng Dou
Publikováno v:
Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background The molecular signaling events involving in high malignancy and poor prognosis of hepatocellular carcinoma (HCC) are extremely complicated. Blockade of currently known targets has not yet led to successful clinical outcome. More u
Externí odkaz:
https://doaj.org/article/84365524b81d423ab59a38cc0d181444
Autor:
Meng Pu, Jianlin Wang, Qike Huang, Ge Zhao, Congcong Xia, Runze Shang, Zhuochao Zhang, Zhenyuan Bian, Xishegn Yang, Kaishan Tao
Publikováno v:
Tumor Biology, Vol 39 (2017)
Hepatocellular carcinoma is one of the most prevalent neoplasms and the leading cause of cancer-related mortality worldwide. Mitochondrial ribosomal protein S23 is encoded by a nuclear gene and participates in mitochondrial protein translation. Mitoc
Externí odkaz:
https://doaj.org/article/d37d6b9c9cc54d419d356e958da22c5a
Publikováno v:
Remote Sensing Letters. 14:402-412
Publikováno v:
IEEE Geoscience and Remote Sensing Letters. 20:1-5
Autor:
Binyong, Liang, Haichuan, Wang, Yu, Qiao, Xue, Wang, Manning, Qian, Xinhua, Song, Yi, Zhou, Yi, Zhang, Runze, Shang, Li, Che, Yifa, Chen, Zhiyong, Huang, Hong, Wu, Satdarshan P, Monga, Yong, Zeng, Diego F, Calvisi, Xiaoping, Chen, Xin, Chen
Publikováno v:
Hepatology. 77:1929-1942
Gain-of-function (GOF) mutations of CTNNB1 and loss-of-function (LOF) mutations of AXIN1 are recurrent genetic alterations in hepatocellular carcinoma (HCC). We aim to investigate the functional contribution of Hippo/YAP/TAZ in GOF CTNNB1 or LOF AXIN
Autor:
Pan, Wang, Runze, Shang, Yue, Ma, Dan, Wang, Wenting, Zhao, Fang, Chen, Xiaosong, Hu, Xiaoyan, Zhao
Publikováno v:
Critical Reviews in Food Science and Nutrition. :1-23
Resveratrol (RSV) is a natural polyphenolic compound detected in grapes, berries, and red wine. The anticancer activities of RSV have been observed in vivo and in vitro studies. However, the pharmacology mechanism of RSV is confusing due to its low b
Autor:
Rong Li, Runze Shang, Shunle Li, Yifan Ren, Lin Shen, Longbao Yang, Shuo Chen, Xi Chen, Junhui Li, Meng Xu
Publikováno v:
Environmental Toxicology. 37:2540-2551
Lysyl-oxidase-like 3 (LOXL3) was reported to be essential in epithelial-mesenchymal transition (EMT) of cancers. However, the role of LOXL3 in hepatocellular carcinoma (HCC) remained unclear. In this study, we explored clinical significance, biologic