Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Runxuan Lin"'
Autor:
Glenn R. Yamakawa, Meshwa Patel, Runxuan Lin, Terence J. O'Brien, Richelle Mychasiuk, Pablo M. Casillas‐Espinosa
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1523-1531 (2023)
Abstract Objectives Growing evidence demonstrates a relationship between epilepsy and the circadian system. However, relatively little is known about circadian function in disease states, such as epilepsy. This study aimed to characterize brain and p
Externí odkaz:
https://doaj.org/article/b09075573573429ab4e896b4a16c581d
Autor:
Xueying Li, Wanhua Qiu, Lu Deng, Jingjing Lin, Wenting Huang, Yuchen Xu, Mulan Zhang, Nigel C. Jones, Runxuan Lin, Huiqin Xu, Li Lin, Peijun Li, Xinshi Wang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Glucocorticoid signalling is closely related to both epilepsy and associated cognitive impairment, possibly through mechanisms involving neuronal apoptosis. As a critical enzyme for glucocorticoid action, the role of 11β-hydroxys
Externí odkaz:
https://doaj.org/article/0b136d42cbb548fca16bcbf087fa8ab5
Autor:
Pablo M. Casillas-Espinosa, Runxuan Lin, Rui Li, Nanditha M. Nandakumar, Georgia Dawson, Emma L. Braine, Benoît Martin, Kim L. Powell, Terence J. O'Brien
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106217- (2023)
Rationale: Low-voltage-activated or T-type Ca2+ channels play a key role in the generation of seizures in absence epilepsy. We have described a homozygous, gain of function substitution mutation (R1584P) in the CaV3.2 T-type Ca2+ channel gene (Cacna1
Externí odkaz:
https://doaj.org/article/b0a167a094254b4caaf3662017799fba
Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer’s Disease-Related Epileptic Seizures
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3676 (2020)
Alzheimer’s disease (AD) is the most common form of dementia. An increasing body of evidence describes an elevated incidence of epilepsy in patients with AD, and many transgenic animal models of AD also exhibit seizures and susceptibility to epilep
Externí odkaz:
https://doaj.org/article/a6330364d2b74347a08dabf0608bbdce
Autor:
Xicui, Sun, Songwei, Duan, Anna, Cao, Bryan, Villagomez, Runxuan, Lin, Hongxia, Chen, Liya, Pi, Bin, Ren, Rong, Chen, Minjie, Chen, Zhekang, Ying, Shenyun, Fang, Qi, Cao
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: Current understanding of amyloid-β protein (Aβ) aggregation and toxicity provides an extensive list of drugs for treating Alzheimer’s disease (AD); however, one of the most promising strategies for its treatment has been tri-peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b4befc2d8241eb1c08986e112e0f5a4
https://pubmed.ncbi.nlm.nih.gov/34368633
https://pubmed.ncbi.nlm.nih.gov/34368633
Unravelling the Role of Glycogen Synthase Kinase-3 in Alzheimer’s Disease-Related Epileptic Seizures
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3676, p 3676 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Alzheimer’s disease (AD) is the most common form of dementia. An increasing body of evidence describes an elevated incidence of epilepsy in patients with AD, and many transgenic animal models of AD also exhibit seizures and susceptibility to epilep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c10a93faa96f6fa14151bdeb0ef6fe49
https://www.mdpi.com/1422-0067/21/10/3676
https://www.mdpi.com/1422-0067/21/10/3676