Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Runsheng He"'
Autor:
Ning Huang, Yuqing Xia, Donghui Zhang, Song Wang, Yitian Bao, Runsheng He, Junlin Teng, Jianguo Chen
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Centriole subdistal appendages (SDAs) anchor microtubules in interphase cells, but their composition and assembly mechanisms are unclear. Here the authors show that two new SDA components, CCDC120 and CCDC68, are required for hierarchical SDA assembl
Externí odkaz:
https://doaj.org/article/95869170b06f433aa908d61ffb11272f
Publikováno v:
Cell Reports, Vol 4, Iss 6, Pp 1100-1107 (2013)
During interphase, centrosomes are connected by a proteinaceous linker between the proximal ends of the centrioles, which is important for the centrosomes to function as a single microtubule-organizing center. However, the composition and regulation
Externí odkaz:
https://doaj.org/article/1f2a0b265a96414bb98471f841ea17a1
Autor:
Keji Zhao, Thomas Ried, Shijie Sheng, M. Margarida Bernardo, Hesed M. Padilla-Nash, Darawalee Wangsa, Runsheng He, Benjamin L. Kidder
Epigenetic regulation of chromatin states is thought to control gene expression programs during lineage specification. However, the roles of repressive histone modifications, such as trimethylated histone lysine 20 (H4K20me3), in development and geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb74b5a2a2c60da466df26742c0877cf
https://doi.org/10.1158/0008-5472.c.6509298.v1
https://doi.org/10.1158/0008-5472.c.6509298.v1
Autor:
Keji Zhao, Thomas Ried, Shijie Sheng, M. Margarida Bernardo, Hesed M. Padilla-Nash, Darawalee Wangsa, Runsheng He, Benjamin L. Kidder
Table S1. Primer sequences for Q-RT-PCR Table S2. SKY Analysis of shLuc ES cells, shSmyd5 ES cells, and shSmyd5 cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2df468b457cd0830609c2a98b492e02
https://doi.org/10.1158/0008-5472.22415448.v1
https://doi.org/10.1158/0008-5472.22415448.v1
Autor:
Keji Zhao, Thomas Ried, Shijie Sheng, M. Margarida Bernardo, Hesed M. Padilla-Nash, Darawalee Wangsa, Runsheng He, Benjamin L. Kidder
Figure S1. Altered differentiation and formation of transformed cells during EB formation of SMYD5 depleted ES cells Figure S2. LTR and LINE repeats are enriched at CNA regions in shSmyd5 cancer cells Figure S3. Expression of G9a in SMYD5-depleted ES
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487a35852f0bc16558766c9e641e0843
https://doi.org/10.1158/0008-5472.22415451
https://doi.org/10.1158/0008-5472.22415451
Autor:
Runsheng He, Besa Xhabija, Lijin K. Gopi, Jiji T. Kurup, Zhishan Xu, Zhe Liu, Benjamin L. Kidder
Publikováno v:
Oncogene
The H3K4 demethylase KDM5B is overexpressed in multiple cancer types, and elevated expression levels of KDM5B is associated with decreased survival. However, the underlying mechanistic contribution of dysregulated expression of KDM5B and H3K4 demethy
Autor:
Xiaofang Cao, Song Yu, Li Lin, Ruikun Cai, Xin Liu, Yequn Chen, Xu Ma, Xuerui Tan, Changlong Guo, Runsheng He, Xingyu Wang, Jian Han, Zuoqi Peng, Chunlin Wang, Shuhua Ni, Qidi Wang, Ying Yang, Lisha An
Publikováno v:
Human Immunology. 80:848-854
Preeclampsia (PE) is one of the major causes of maternal and perinatal mortality worldwide. This study aimed to determine the immunological characteristics of PE patients and normal pregnancy at the T cell receptor beta-chain (TRB) level by using hig
Autor:
Junyu Xiao, Qisheng Wang, Ning Gao, Yinghui Zheng, Qi Lv, Y Cao, Yajin Qu, Guopeng Wang, Wenjie Zhao, Hua Xu, Feifei Qi, Qinyu Zhu, Hua Zhu, Yali Bai, Jianhui Nie, Ruixue Liu, Ayijiang Yisimayi, Jiangning Liu, Haoyu Liang, Xiao-Xia Du, Wei Deng, Bo Wang, Pin Yu, Weijin Huang, Xiao-Dong Su, Shuo Du, X. Sunney Xie, Shuran Gong, Runsheng He, Chenggong Ji, Chuan Qin, Xiang Gao, Youchun Wang, Linlin Bao, Yunlin Han
Publikováno v:
Cell
Understanding how potent neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is critical for effective therapeutic development. We previously described BD-368-2, a SARS-CoV-2 NAb with high potency; however, its neutralization mechanism is largely unkno
Autor:
Runsheng He, Xiao-Xia Du, Chenggong Ji, Sunney Xie, Yali Bai, Junyu Xiao, Ning Gao, Yinghui Zheng, Ayijiang Yisimayi, Bo Wang, Guopeng Wang, Shuo Du, Qisheng Wang, Qinyu Zhu, Xiao-Dong Su, Hua Xu, Y Cao
SummaryUnderstanding the mechanism of neutralizing antibodies (NAbs) against SARS-CoV-2 is critical for effective vaccines and therapeutics development. We recently reported an exceptionally potent NAb, BD-368-2, and revealed the existence ofVH3-53/V
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ddcda909dfbafe57d36eb9159409bd
https://doi.org/10.1101/2020.07.09.195263
https://doi.org/10.1101/2020.07.09.195263
Autor:
Zongmin Du, Cheng-Feng Qin, Guopeng Wang, Yong-Qiang Deng, Qi Lv, Chuan Qin, Qinyu Zhu, Yinghui Zheng, Ning Gao, Hua Zhu, Xiao-Dong Su, Yanfeng Xu, Xiao-Xia Du, Yafang Tan, X. Sunney Xie, Xu Zhang, Junyu Xiao, Yanjun Wang, Chenyang Geng, Jiangning Liu, Bin Su, Liyang Song, Ronghua Jin, Yingmei Feng, Linlin Bao, Y Cao, Luxin Qiao, Wei Deng, Xiaoran Chai, Runsheng He, Wenjie Sun, Xiaofeng Li, Xianghua Guo
Publikováno v:
Cell
The COVID-19 pandemic urgently needs therapeutic and prophylactic interventions. Here, we report the rapid identification of SARS-CoV-2-neutralizing antibodies by high-throughput single-cell RNA and VDJ sequencing of antigen-enriched B cells from 60