Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Runping Duan"'
Dietary caloric restriction protects experimental autoimmune uveitis by regulating Teff/Treg balance
Autor:
Zhaohuai Li, Runping Duan, Qi Jiang, Jiaying Liu, Jialing Chen, Loujing Jiang, Tianfu Wang, He Li, Yihan Zhang, Xuening Peng, Zhaohao Huang, Lei Zhu, Wenjun Zou, Ying Lin, Wenru Su
Publikováno v:
iScience, Vol 27, Iss 12, Pp 111279- (2024)
Summary: Uveitis, an autoimmune disease, often leads to blindness. CD4+ T cells, including regulatory T cells (Tregs) and effector T cells (Th1 and Th17), play a critical role in its pathogenesis. Caloric restriction (CR) has been shown to alleviate
Externí odkaz:
https://doaj.org/article/bfb582b9826d4c518a9b3634667be71a
Autor:
Xiuxing Liu, Yuhan Su, Zhaohao Huang, Jianjie Lv, Chenyang Gu, Zhuang Li, Tianyu Tao, Yidan Liu, Qi Jiang, Runping Duan, Binyao Chen, Rong Ju, Xianggui Wang, Yingfeng Zheng, Wenru Su
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 5, Pp n/a-n/a (2023)
Abstract Background Sleep loss (SL) is a health issue associated with the higher risk of autoimmune and inflammatory disorders. However, the connection between SL, the immune system, and autoimmune diseases remains unknown. Methods We conducted mass
Externí odkaz:
https://doaj.org/article/acd9445e7a1d453493e3bf067c69c366
Autor:
Yuehan Gao, Runping Duan, He Li, Loujing Jiang, Tianyu Tao, Xiuxing Liu, Lei Zhu, Zhaohuai Li, Binyao Chen, Songguo Zheng, Xianchai Lin, Wenru Su
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106729- (2023)
Summary: Gingiva-derived mesenchymal stem cells (GMSCs) have shown astonishing efficacy in the treatment of various autoimmune diseases. However, the mechanisms underlying these immunosuppressive properties remain poorly understood. Here, we generate
Externí odkaz:
https://doaj.org/article/8445091f80c44d4898362191233328e0
Autor:
Xiuxing Liu, Qi Jiang, Jianjie Lv, Shizhao Yang, Zhaohao Huang, Runping Duan, Tianyu Tao, Zhaohuai Li, Rong Ju, Yingfeng Zheng, Wenru Su
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Vogt-Koyanagi-Harada disease (VKH) is an important refractory uveitis mediated by pathological T cells (TCs). Tofacitinib (TOFA) is a JAK- targeted therapy for several autoimmune diseases. However, the specific pathogenesis and targeted therapeutics
Externí odkaz:
https://doaj.org/article/6cd4c1a654e34e1083edf2a3e91eac6b
Autor:
Xiuxing Liu, Binyao Chen, Zhaohao Huang, Runping Duan, He Li, Lihui Xie, Rong Wang, Zhaohuai Li, Yuehan Gao, Yingfeng Zheng, Wenru Su
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Liu et al. use mass cytometry and single-cell RNA sequencing of healthy human blood samples to obtain a comprehensive human immune cell landscape when sleep duration is reduced. Their findings could provide highdimensional insight into the cellular a
Externí odkaz:
https://doaj.org/article/e8dc70b7415c4a6babbdda9affd52feb
Autor:
Yesheng Xu, Ming Kong, Wenjia Xie, Runping Duan, Zhengqing Fang, Yuxiao Lin, Qiang Zhu, Siliang Tang, Fei Wu, Yu-Feng Yao
Publikováno v:
Engineering, Vol 7, Iss 7, Pp 1002-1010 (2021)
Infectious keratitis is the most common condition of corneal diseases in which a pathogen grows in the cornea leading to inflammation and destruction of the corneal tissues. Infectious keratitis is a medical emergency for which a rapid and accurate d
Externí odkaz:
https://doaj.org/article/d315dbc9d9124691899e58c96abbed53
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/10fe95f402e8472dbe5fae8f06a7af06
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Uveitis is an inflammation of the iris, ciliary body, vitreous, retina, or choroid, which has been shown to be the first manifestation of numerous systemic diseases. Studies about the immunopathogenesis and treatment of uveitis are helpful to compreh
Externí odkaz:
https://doaj.org/article/fa7ce6b4ebc14197ba436b6bbde7492e
Autor:
He Li, Yuehan Gao, Lihui Xie, Rong Wang, Runping Duan, Zhaohuai Li, Binyao Chen, Lei Zhu, Xianggui Wang, Wenru Su
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Glucocorticoids (GCs) are widely used immunosuppressive drugs for autoimmune diseases, although considerable gaps exist between current knowledge of the mechanisms of GCs and their conclusive immune-regulatory effects. Here we generated a single-cell
Externí odkaz:
https://doaj.org/article/04162b452db64c7789e691775f0d74e1
Autor:
Qiang Zhu, Wen-jia Xie, Runping Duan, Siliang Tang, Yu-Feng Yao, Zhengqing Fang, Fei Wu, Ming Kong, Ye-sheng Xu, Yuxiao Lin
Publikováno v:
Engineering, Vol 7, Iss 7, Pp 1002-1010 (2021)
Infectious keratitis is the most common entities of corneal diseases, in which pathogen grows in the cornea leading to inflammation and destruction of the corneal tissues. Infectious keratitis is a medical emergency, for which a rapid and accurate di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e6a7494e14c2ac5b8aeac061b65c5a
https://doi.org/10.1016/j.eng.2020.04.012
https://doi.org/10.1016/j.eng.2020.04.012