Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Runhui Liu"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Host defense peptide (HDP)-mimicking polymers are promising therapeutic alternatives to antibiotics and have large-scale untapped potential. Artificial intelligence (AI) exhibits promising performance on large-scale chemical-content design,
Externí odkaz:
https://doaj.org/article/406a5d3c36624e739ac6ed0fc585e070
Autor:
Yu Zou, Yue Chai, Hongming Shao, Shuyu Wang, Ruilin Hou, Runhui Liu, Linjing Zhao, Chunlin Zhuang
Publikováno v:
Pharmaceutical Fronts, Vol 06, Iss 03, Pp e283-e293 (2024)
Necroptosis, a caspase-independent regulated cell death, is primarily mediated by the serine/threonine kinases RIPK1 and RIPK3, and the mixed lineage kinase domain-like protein (MLKL). Targeting necroptosis is a validated therapeutic strategy for var
Externí odkaz:
https://doaj.org/article/aa3a0370b76a4ad48cfe6d0e08a80029
Autor:
Wanlin Li, Ximian Xiao, Yuchen Qi, Xiuhui Lin, Huiqun Hu, Minqi Shi, Min Zhou, Weinan Jiang, Longqiang Liu, Kang Chen, Kai Wang, Runhui Liu
Publikováno v:
Research, Vol 6 (2023)
Host defense peptides (HDPs) are one of the potentially promising agents for infection diseases due to their broad spectrum and low resistance rate, but their clinical applications are limited by proteolytic instability, high-cost, and complicated sy
Externí odkaz:
https://doaj.org/article/208e78d1d1334cb597257644ab1a7498
Autor:
Ziyi Lu, Yueming Wu, Zihao Cong, Yuxin Qian, Xue Wu, Ning Shao, Zhongqian Qiao, Haodong Zhang, Yunrui She, Kang Chen, Hengxue Xiang, Bin Sun, Qian Yu, Yuan Yuan, Haodong Lin, Meifang Zhu, Runhui Liu
Publikováno v:
Bioactive Materials, Vol 6, Iss 12, Pp 4531-4541 (2021)
It is an urgent need to tackle drug-resistance microbial infections that are associated with implantable biomedical devices. Host defense peptide-mimicking polymers have been actively explored in recent years to fight against drug-resistant microbes.
Externí odkaz:
https://doaj.org/article/6f684ac9a0d34e64824ad60f51542bcc
Autor:
Donghui Zhang, Jingjing Liu, Qi Chen, Weinan Jiang, Yibing Wang, Jiayang Xie, Kaiqian Ma, Chao Shi, Haodong Zhang, Minzhang Chen, Jianglin Wan, Pengcheng Ma, Jingcheng Zou, Wenjing Zhang, Feng Zhou, Runhui Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Functionalisation of hydrogels can be difficult to achieve and often requires modification of polymers before gelation. Here, the authors report on a sandcastle worm inspired adhesive tripeptide for the post gelation functionalisation of wet hydrogel
Externí odkaz:
https://doaj.org/article/3dda43816f5344b59803dbef454e9896
Autor:
Jiayang Xie, Min Zhou, Yuxin Qian, Zihao Cong, Sheng Chen, Wenjing Zhang, Weinan Jiang, Chengzhi Dai, Ning Shao, Zhemin Ji, Jingcheng Zou, Ximian Xiao, Longqiang Liu, Minzhang Chen, Jin Li, Runhui Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacter
Externí odkaz:
https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20
Autor:
Donghui Zhang, Qi Chen, Yufang Bi, Haodong Zhang, Minzhang Chen, Jianglin Wan, Chao Shi, Wenjing Zhang, Junyu Zhang, Zhongqian Qiao, Jin Li, Shengfu Chen, Runhui Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Implantation-caused foreign-body response is a commonly encountered issue and can result in failure of implants. Here, the authors demonstrate that a highly water soluble, biocompatible, and easily accessible poly-DL-serine hydrogel can mitigate fore
Externí odkaz:
https://doaj.org/article/5569e69502f244028056aa2e6bff787c
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Atherosclerosis (AS) and the accompanied cardiovascular diseases (CVDs) were the leading cause of death worldwide. Recently, the association between CVDs, gut microbiota, and metabolites had aroused increasing attention. In the study, we headed our i
Externí odkaz:
https://doaj.org/article/9bc14a02ee7d41d29a358b616601e03f
Autor:
Min Zhou, Ruxin Cui, Zhengjie Luo, Zihao Cong, Ning Shao, Ling Yuan, Jiawei Gu, Hongyan He, Runhui Liu
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 7, p 382 (2023)
Polyethylene glycol (PEG)–doxorubicin (DOX) conjugation is an important strategy to improve toxicity and enhance clinically therapeutic efficacy. However, with the frequent use of PEG-modified drugs, the accumulation of anti-PEG antibodies has beco
Externí odkaz:
https://doaj.org/article/695d1a9d054d479ca23ce05c43679125
Autor:
Wenjing Zhang, Yueming Wu, Qi Chen, Haodong Zhang, Min Zhou, Kang Chen, Chuntao Cao, Han Guo, Jianrong Xu, Honglai Liu, Haodong Lin, Changsheng Liu, Runhui Liu
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract Growth factors (GFs) play important roles in biological system and are widely used in tissue regeneration. However, their application is greatly hindered by short in vivo lifetime of GFs. GFs are bound to fibronectin dynamically in the extra
Externí odkaz:
https://doaj.org/article/a9d5beeb291f477ab79ba0b826d39df8