Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rune Toftgard"'
Autor:
Marco Gerling, Nikè V. J. A. Büller, Leonard M. Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul V. Kuiper, Leander Blaas, Mattheus C. B. Wielenga, Sven Almer, Anja A. Kühl, Erik Fredlund, Gijs R. van den Brink, Rune Toftgård
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
The Hedgehog signalling pathway can drive tumorigenesis. Here, the authors show that in a colitis-associated colon cancer model downstream Hedgehog signalling is restricted to the stroma and its over-activation can inhibit tumorigenesis, associated w
Externí odkaz:
https://doaj.org/article/3935658324894f5a9a9d4187bc7ac949
Autor:
Madeleen Bosma, Marco Gerling, Jenny Pasto, Anastasia Georgiadi, Evan Graham, Olga Shilkova, Yasunori Iwata, Sven Almer, Jan Söderman, Rune Toftgård, Fredrik Wermeling, Elisabeth Almer Boström, Pontus Almer Boström
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
FDNC4 is a poorly characterized homologue of FNDC5/irisin, a myokine induced by exercise. Here the authors show that FDNC4 increases macrophage survival in growth factor deprivation, inhibits phagocytosis and transcriptional responses to M1 and M2 po
Externí odkaz:
https://doaj.org/article/17b58db1f2fe4257b1e5e50f6ef241f8
Autor:
Marco Gerling, Nikè V.J.A. Büller, Leonard M Kirn, Simon Joost, Oliver Frings, Benjamin Englert, Åsa Bergström, Raoul V. Kuiper, Leander Blaas, Mattheus C. B. Wielenga, Sven Almer, Anja A. Kühl, Erik Fredlund, Gijs R. van den Brink, Rune Toftgård
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-2 (2016)
Nature Communications 7:12321 doi: (2016); Published 5 Aug 2016; Updated 13 Sep 2016 In Fig. 6f of this Article, the labelling of the two immunohistochemistry images was inadvertently changed from ‘Haematoxylin, ki67’ to ‘Haematoxylin, Casp-3
Externí odkaz:
https://doaj.org/article/b0cffc70de824cc8bc75273b919c7b05
Autor:
Satu Massinen, Marie-Estelle Hokkanen, Hans Matsson, Kristiina Tammimies, Isabel Tapia-Páez, Vanina Dahlström-Heuser, Juha Kuja-Panula, Jan Burghoorn, Kristian E Jeppsson, Peter Swoboda, Myriam Peyrard-Janvid, Rune Toftgård, Eero Castrén, Juha Kere
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e20580 (2011)
DCDC2 is one of the candidate susceptibility genes for dyslexia. It belongs to the superfamily of doublecortin domain containing proteins that bind to microtubules, and it has been shown to be involved in neuronal migration. We show that the Dcdc2 pr
Externí odkaz:
https://doaj.org/article/ddfd00b63e7e452f9a300c2d098793a9
Autor:
Hira Lal Goel, Tatiana Gritsko, Bryan Pursell, Cheng Chang, Leonard D. Shultz, Dale L. Greiner, Jens Henrik Norum, Rune Toftgard, Leslie M. Shaw, Arthur M. Mercurio
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 747-761 (2014)
Although the α6β1 integrin has been implicated in the function of breast and other cancer stem cells (CSCs), little is known about its regulation and relationship to mechanisms involved in the genesis of CSCs. We report that a CD44high/CD24low popu
Externí odkaz:
https://doaj.org/article/4e1a162adbeb445b9041895eb6512251
Autor:
Dianqing Wu, Guanqing Wu, Wei Xie, Peter Maye, Priit Kogerman, Junhao Mao, Francisco J. Tejedor, Rune Toftgard
Publikováno v:
Journal of Biological Chemistry. 277:35156-35161
To investigate the cellular role of dual specificity Yak1-related kinase (Dyrk) 1, a nuclear localized dual specificity protein kinase, we examined its effect on transcriptional regulation using reporter gene assays. We found that Dyrk1 can substanti
Autor:
Anja Füllgrabe, Simon Joost, Alexandra Are, Tina Jacob, Unnikrishnan Sivan, Andrea Haegebarth, Sten Linnarsson, Benjamin D. Simons, Hans Clevers, Rune Toftgård, Maria Kasper
Publikováno v:
Stem Cell Reports, Vol 5, Iss 5, Pp 843-855 (2015)
The dynamics and interactions between stem cell pools in the hair follicle (HF), sebaceous gland (SG), and interfollicular epidermis (IFE) of murine skin are still poorly understood. In this study, we used multicolor lineage tracing to mark Lgr6-expr
Externí odkaz:
https://doaj.org/article/236350be9ef3410da8d307bbf455eb10