Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rune Nørgaard Rasmussen"'
Publikováno v:
FEBS Open Bio, Vol 9, Iss 6, Pp 1071-1081 (2019)
Nuclear factor of activated T cells 5 (NFAT5) is a transcription factor involved in the regulation of several genes involved in the response to extracellular hyperosmolality. Recently, the uptake of ibuprofen by an as yet unknown carrier was suggeste
Externí odkaz:
https://doaj.org/article/c85ba85a8bab4f54ac31d4beb8a8c5d8
Publikováno v:
Rasmussen, R N, Lagunas, C, Plum, J M, Holm, R & Nielsen, C U 2016, ' Interaction of GABA-mimetics with the taurine transporter (TauT, Slc6a6) in hyperosmotic treated caco-2, LLC-PK1 and rat renal SKPT cells ', European Journal of Pharmaceutical Sciences, vol. 82, pp. 138-146 . https://doi.org/10.1016/j.ejps.2015.11.020
The aim of the present study was to investigate if basic GABA-mimetics interact with the taurine transporter (TauT, Slc6a6), and to find a suitable cell based model that is robust towards extracellular changes in osmolality during uptake studies. Tau
Publikováno v:
Rasmussen, R N, Holm, R, Vielsted Christensen, K & Nielsen, C U 2016, ' Ibuprofen transport in renal cell cultures : Characterization of an ibuprofen transporter upregulated by hyperosmolarity ', MedChemComm, vol. 7, no. 10, pp. 1916-1924 . https://doi.org/10.1039/C6MD00305B
In the present study, we have investigated ibuprofen transport in renal cell cultures with the aim of characterizing a recently proposed ibuprofen transporter. We here show that hyperosmolarity upregulates an ibuprofen transporter in dog renal MDCK I
Publikováno v:
Rasmussen, R N, Christensen, K V, Holm, R & Nielsen, C U 2018, ' Hyperosmolality regulates mRNA expression of membrane transporters in renal MDCK I cells ', Northern Pharma Network Meeting & POP Kick off-Meeting Conference, Odense, Denmark, 29/01/2018-31/01/2018 .
University of Southern Denmark
University of Southern Denmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::01d68847395039c568208983d35e6736
https://portal.findresearcher.sdu.dk/da/publications/b4a43f5a-ec5c-423b-b46d-d73b57de380d
https://portal.findresearcher.sdu.dk/da/publications/b4a43f5a-ec5c-423b-b46d-d73b57de380d
Autor:
Benafsha Noori, Martha Kampp Nøhr, Candela Lagunas, Carsten Uhd Nielsen, Junying Mo, Rune Nørgaard Rasmussen, René Holm
Publikováno v:
Nielsen, C U, Rasmussen, R N, Mo, J, Noori, B, Lagunas, C, Holm, R & Nøhr, M K 2016, ' A Transporter of Ibuprofen is Upregulated in MDCK I cells under Hyperosmotic Culture Conditions ', Molecular Pharmaceutics, vol. 13, no. 9, pp. 3119-3129 . https://doi.org/10.1021/acs.molpharmaceut.6b00330
Ibuprofen is a widely used drug. It has been identified as an inhibitor of several transporters, but it is not clear if ibuprofen is a substrate of any transporter itself. In the present work, we have characterized a transporter of ibuprofen, which i
Publikováno v:
Rasmussen, R N, Vielsted Christensen, K, Holm, R & Nielsen, C U 2016, ' Hyperosmolality regulates transporters in renal MDCK I cells ', The Annual Meeting of the Danish Chemical Society, Odense, Danmark, 09/06/2016-09/06/2016 .
University of Southern Denmark
University of Southern Denmark
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::37f82eb694e1a8d9953ccbe46b25e901
https://portal.findresearcher.sdu.dk/da/publications/1ee2f949-d709-4ee0-8b8f-2baf02c2fdfb
https://portal.findresearcher.sdu.dk/da/publications/1ee2f949-d709-4ee0-8b8f-2baf02c2fdfb