Výsledky vyhledávání - "Rune Jemtland"

The Glucocorticoid-Induced Leucine Zipper Gene (GILZ) Expression Decreases after Successful Treatment of Patients with Endogenous Cushing's Syndrome and May Play a Role in Glucocorticoid-Induced Osteoporosis

Autor: Jens Bollerslev, Rune Jemtland, Tove Lekva, Cybèle Kristo, Ole Kristoffer Olstad, Thor Ueland

Publikováno v: Endocrine reviews. 30(7)

Glucocorticoid-induced bone loss is a serious complication in patients with endogenous Cushing's syndrome. However, the mechanism(s) by which excess glucocorticoids influence bone metabolism is not completely understood.The aim of the study was to in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8a1142f2eecb92923d2348d35518a3
https://pubmed.ncbi.nlm.nih.gov/28199557

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Eight genes are highly associated with BMD variation in postmenopausal Caucasian women

Autor: Arnoldo Frigessi, Finn P. Reinholt, Vigdis T. Gautvik, Rune Jemtland, Marit Holden, Per I. Høvring, Hilde Refvem, Sjur Reppe, Ole Kristoffer Olstad, Kaare M. Gautvik

Publikováno v: Bone. 46:604-612

Low bone mineral density (BMD) is an important risk factor for skeletal fractures which occur in about 40% of women >/=50 years in the western world. We describe the transcriptional changes in 84 trans-iliacal bone biopsies associated with BMD variat

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https://doi.org/10.1016/j.bone.2009.11.007

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How can antiepileptic drugs affect bone mass, structure and metabolism? Lessons from animal studies

Autor: Erik Taubøll, Sigrid Svalheim, Rune Jemtland, Leif Gjerstad, Lise Sofie H. Nissen-Meyer, Finn P. Reinholt

Publikováno v: Seizure. 17:187-191

SummaryPatients with epilepsy, treated with antiepileptic drugs (AEDs) are at increased risk of fractures. Although several commonly used AEDs reduce bone mass in patients, the mechanisms are only scarcely known. In this review, we focus on the usefu

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https://doi.org/10.1016/j.seizure.2007.11.024

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Levetiracetam, Phenytoin, and Valproate Act Differently on Rat Bone Mass, Structure, and Metabolism

Autor: Erik Taubøll, Sigrid Svalheim, Lise Sofie H. Nissen-Meyer, Gunhild Melhus, Lene B. Solberg, Finn P. Reinholt, Sjur Reppe, Rune Jemtland, Tove Lekva, Leif Gjerstad

Publikováno v: Epilepsia. 48:1850-1860

Summary: Purpose: Long-term treatment with antiepileptic drugs (AEDs) is associated with increased risk of fractures. Phenytoin (PHT) and valproate (VPA) have both been suggested to influence bone health, whereas levetiracetam (LEV) is scarcely studi

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https://doi.org/10.1111/j.1528-1167.2007.01176.x

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Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice

Autor: Mona Elisabeth Pedersen, Andrea Del Fattore, Nadia Rucci, Sjur Reppe, Dominique D. Pierroz, Dario Fortunati, Rita Paro, Serge Ferrari, Kaare M. Gautvik, Anna Teti, Rune Jemtland, Vigdis T. Gautvik, Vincent A. Stadelmann, Finn P. Reinholt, Lise Sofie H. Nissen-Meyer

Publikováno v: Journal of Cell Science. 120:2785-2795

The transcription factor Sox4 is vital for fetal development, as Sox4–/– homozygotes die in utero. Sox4 mRNA is expressed in the early embryonic growth plate and is regulated by parathyroid hormone, but its function in bone modeling/remodeling is

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https://doi.org/10.1242/jcs.003855

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Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells

Autor: Sjur Reppe, Kaare M. Gautvik, Ole Kristoffer Olstad, Edith Rian, Rune Jemtland, Vigdis T. Gautvik

Publikováno v: Biochemical and Biophysical Research Communications. 324:218-223

Parathyroid hormone (PTH) exerts potent and diverse effects in bone and cartilage through activation of type 1 PTH receptors (PTH1R) capable of coupling to protein kinase A (PKA) and PKC. We have used macroarrays to identify zinc finger protein butyr

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https://doi.org/10.1016/j.bbrc.2004.09.030

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Prognostic value of osteoprotegerin in heart failure after acute myocardial infarction

Autor: Lars Gullestad, Kenneth Dickstein, Pål Aukrust, John Kjekshus, Jens Bollerslev, Torbjørn Omland, Thor Ueland, Iain B. Squire, Kristin Godang, Aina Hognestad, Rune Jemtland

Publikováno v: Journal of the American College of Cardiology. 44:1970-1976

OBJECTIVES We sought to determine the relationship between osteoprotegerin (OPG) and clinical outcomes in patients with heart failure (HF) after acute myocardial infarction (AMI). BACKGROUND Arterial calcification is a prominent feature of arterial a

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https://doi.org/10.1016/j.jacc.2004.06.076

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Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion

Autor: Rune Jemtland, Kaechoong Lee, P. Divieti, Gino V. Segre

Publikováno v: Bone. 32:611-620

We used both clonal osteoblast-like cells and primary calvarial osteoblastic cells to examine the role of Hedgehog in osteoblast biology. Primary osteoblasts and several clonal osteoblast-like cell lines express Indian hedgehog (Ihh), and genes encod

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https://doi.org/10.1016/s8756-3282(03)00092-9

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Sox-4 Messenger RNA Is Expressed in the Embryonic Growth Plate and Regulated via the Parathyroid Hormone/Parathyroid Hormone-Related Protein Receptor in Osteoblast-like Cells

Autor: Rune Jemtland, Sjur Reppe, Kaare M. Gautvik, Ole Kristoffer Olstad, Vigdis T. Gautvik, Edith Rian

Publikováno v: Journal of Bone and Mineral Research. 15:2402-2412

Parathyroid hormone (PTH) and PTH-related protein (PTHrP) exert potent and diverse effects in cells of the osteoblastic and chondrocytic lineages. However, downstream mediators of these effects are characterized inadequately. We identified a compleme

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https://doi.org/10.1359/jbmr.2000.15.12.2402

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Two Human Osteoblast-like Osteosarcoma Cell Lines Show Distinct Expression and Differential Regulation of Parathyroid Hormone-Related Protein

Autor: Kaare M. Gautvik, Elisabet Bucht, Egil Haug, Edith Rian, Øyvind S. Bruland, Ole Kristoffer Olstad, Rune Jemtland

Publikováno v: Journal of Bone and Mineral Research. 14:904-914

Parathyroid hormone (PTH)-related protein (PTHrP) acts as a local regulator of osteoblast function via mechanisms that involve PTH/PTHrP receptors linked to protein kinase A (PKA) and C (PKC). However, the regulation of PTHrP production and mRNA expr

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https://doi.org/10.1359/jbmr.1999.14.6.904

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