Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Rune Brautaset"'
Autor:
Anne Rombaut, Danica Jovancevic, Raymond Ching-Bong Wong, Alan Nicol, Rune Brautaset, David I. Finkelstein, Christine T. O. Nguyen, James R. Tribble, Pete A. Williams
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Neurodegenerative diseases have common underlying pathological mechanisms including progressive neuronal dysfunction, axonal and dendritic retraction, and mitochondrial dysfunction resulting in neuronal death. The retina is often affected in
Externí odkaz:
https://doaj.org/article/ce457f07715247b08e1d0a372c5df54f
Autor:
Jonas E. Svensson, Martin Bolin, Daniel Thor, Pete A. Williams, Rune Brautaset, Marcus Carlsson, Peder Sörensson, David Marlevi, Rubens Spin-Neto, Monika Probst, Göran Hagman, Anton Forsberg Morén, Miia Kivipelto, Pontus Plavén-Sigray
Publikováno v:
BMC Neurology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Rapamycin is an inhibitor of the mechanistic target of rapamycin (mTOR) protein kinase, and preclinical data demonstrate that it is a promising candidate for a general gero- and neuroprotective treatment in humans. Results from mo
Externí odkaz:
https://doaj.org/article/6432726833fc4d12a5cd09fe328089f3
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Leber’s hereditary optic neuropathy (LHON) is driven by mtDNA mutations affecting Complex I presenting as progressive retinal ganglion cell dysfunction usually in the absence of extra-ophthalmic symptoms. There are no long-term neuroprotec
Externí odkaz:
https://doaj.org/article/c38a73fa7f8049deb758ef1af5f2a4a5
Autor:
Alberto Domínguez-Vicent, Abinaya Priya Venkataraman, Amanda Dalin, Rune Brautaset, Robert Montés-Micó
Publikováno v:
Eye and Vision, Vol 10, Iss 1, Pp 1-9 (2023)
Abstract Background To evaluate the repeatability of a fully automated swept-source optical coherence tomography (SS-OCT) and its agreement with an optical low coherence reflectometry (OLCR) for several biometric parameters. Methods In this study, 74
Externí odkaz:
https://doaj.org/article/38c0c1191dca4a7cb7ddffbedf330a06
Publikováno v:
Frontiers in Ophthalmology, Vol 3 (2023)
Glaucoma is the leading cause of irreversible blindness. Current treatment options are limited and often only slow disease progression. Metabolic dysfunction has recently been recognized as a key early and persistent mechanism in glaucoma pathophysio
Externí odkaz:
https://doaj.org/article/5e0a6e3bbd9142cb9aa51537fa8e23ce
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The similarities between horizontal and vertical Optical Coherence Tomography (OCT) scans for the individual retinal layer thickness measurements in the macula was evaluated. Two volumetric scans (B-scans oriented horizontally and vertically
Externí odkaz:
https://doaj.org/article/1dccc97ab129452793543b34f250e073
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0278269 (2022)
PurposeTo evaluate the precision of objective refraction measurements with six different autorefractors that have different designs and measurement principles and to compare the objective refraction values with the subjective refraction.MethodObjecti
Externí odkaz:
https://doaj.org/article/2706d53b5e8f41d8ad1f1674d4837776
Autor:
Alberto Domínguez-Vicent, Jesper Kensén, Marika Wahlberg Ramsay, Rune Brautaset, Abinaya Priya Venkataraman
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Purpose: To evaluate the precision of individual and combined macula and optic disc volumetric analysis, and the agreement between these two scan modes with spectral domain optical coherence tomography (OCT).Methods: Macular and optic disc volumetric
Externí odkaz:
https://doaj.org/article/0ad9e984069b4b75b7872534c6018bcf
Autor:
James R. Tribble, Amin Otmani, Shanshan Sun, Sevannah A. Ellis, Gloria Cimaglia, Rupali Vohra, Melissa Jöe, Emma Lardner, Abinaya P. Venkataraman, Alberto Domínguez-Vicent, Eirini Kokkali, Seungsoo Rho, Gauti Jóhannesson, Robert W. Burgess, Peter G. Fuerst, Rune Brautaset, Miriam Kolko, James E. Morgan, Jonathan G. Crowston, Marcela Votruba, Pete A. Williams
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101988- (2021)
Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to
Externí odkaz:
https://doaj.org/article/11535b7d2b994327966f83eaacbf9faa
Autor:
Alejandro Cerviño, Jose F. Alfonso, Hema Radhakrishnan, Jose M. González-Meijome, Rune Brautaset
Publikováno v:
Journal of Ophthalmology, Vol 2020 (2020)
Externí odkaz:
https://doaj.org/article/108ca92b98c54fb985600f46ba90877e