Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Rune A Høglund"'
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62237 (2013)
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative disease. It is thought to be mediated by CD4(+) Th1/Th17 cells. More recently, cells of the innate immune system such as dendritic cells (DCs) and natu
Externí odkaz:
https://doaj.org/article/e558fdc9554f45d0825cf24b52b910cb
Autor:
Abhilash D Pandya, Zaidoon Al-Jaderi, Rune A Høglund, Trygve Holmøy, Hanne F Harbo, Johannes Norgauer, Azzam A Maghazachi
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26780 (2011)
BACKGROUND: Natural killer (NK) cells have both cytolytic and immunoregulatory functions. We recently described that these cells release the inflammatory cytokines IL-17 and IFN-γ. However, the precise identity of the NK cell subset(s) that secrete
Externí odkaz:
https://doaj.org/article/153c7a7a2c914069b79ec57e9abff285
Autor:
Rune A. Høglund, Andreas Lossius, Jorunn N. Johansen, Jane Homan, Jūratė Šaltytė Benth, Harlan Robins, Bjarne Bogen, Robert D. Bremel, Trygve Holmøy
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Memory B cells acting as antigen-presenting cells are believed to be important in multiple sclerosis (MS), but the antigen they present remains unknown. We hypothesized that B cells may activate CD4+ T cells in the central nervous system of MS patien
Externí odkaz:
https://doaj.org/article/23c0957f1c094b83bef38b9a1c64e24b
Autor:
Ida Lindeman, Justyna Polak, Shuo‐Wang Qiao, Trygve Holmøy, Rune A. Høglund, Frode Vartdal, Pål Berg‐Hansen, Ludvig M. Sollid, Andreas Lossius
Publikováno v:
European journal of immunologyReferences. 52(4)
Clonally related B cells infiltrate the brain, meninges, and cerebrospinal fluid of MS patients, but the mechanisms driving the B-cell response and shaping the immunoglobulin repertoires remain unclear. Here, we used single-cell full-length RNA-seq a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1362c209a7424e108887f025fe192e
https://pubmed.ncbi.nlm.nih.gov/35094395
https://pubmed.ncbi.nlm.nih.gov/35094395
Autor:
Rune A. Høglund, Robert D. Bremel, E. Jane Homan, Silje Bøen Torsetnes, Andreas Lossius, Trygve Holmøy
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
B cells are important pathogenic players in multiple sclerosis (MS), but their exact role is not known. We have previously demonstrated that B cells from cerebrospinal fluid (CSF) of MS patients can activate T cells that specifically recognize antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36e857a7df7b20ee831164345e8bdf56
http://hdl.handle.net/10852/84516
http://hdl.handle.net/10852/84516
Publikováno v:
Journal of Neurology
Holmøy, T, Høglund, R A, Illes, Z, Myhr, K M & Torkildsen, Ø 2021, ' Recent progress in maintenance treatment of neuromyelitis optica spectrum disorder ', Journal of Neurology, vol. 268, no. 12, pp. 4522-4536 . https://doi.org/10.1007/s00415-020-10235-5
Holmøy, T, Høglund, R A, Illes, Z, Myhr, K M & Torkildsen, Ø 2021, ' Recent progress in maintenance treatment of neuromyelitis optica spectrum disorder ', Journal of Neurology, vol. 268, no. 12, pp. 4522-4536 . https://doi.org/10.1007/s00415-020-10235-5
Background Treatment of neuromyelitis optica spectrum disorder (NMOSD) has so far been based on retrospective case series. The results of six randomized clinical trials including five different monoclonal antibodies targeting four molecules and three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19586701e509b5f72a316112e8150d29
https://hdl.handle.net/11250/2739748
https://hdl.handle.net/11250/2739748
Autor:
Rune A, Høglund, Robert D, Bremel, E Jane, Homan, Silje Bøen, Torsetnes, Andreas, Lossius, Trygve, Holmøy
Publikováno v:
Frontiers in Immunology
B cells are important pathogenic players in multiple sclerosis (MS), but their exact role is not known. We have previously demonstrated that B cells from cerebrospinal fluid (CSF) of MS patients can activate T cells that specifically recognize antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69171c6f88fdcff98fce996fc25a8886
https://pubmed.ncbi.nlm.nih.gov/32328067
https://pubmed.ncbi.nlm.nih.gov/32328067
Publikováno v:
Tidsskrift for Den norske legeforening.
Background Anti-MOG encephalomyelitis is a recently described demyelinating, autoimmune disease of the central nervous system, identified by antibodies against myelin oligodendrocyte glycoprotein (MOG). Case presentation A previously healthy 20-year-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::138eee312c7078794725b6106802052d
https://doi.org/10.4045/tidsskr.19.0122
https://doi.org/10.4045/tidsskr.19.0122
Autor:
Bjarne Bogen, Robert D. Bremel, Silje Bøen Torsetnes, Andreas Lossius, Trygve Holmøy, E. Jane Homan, Rune Alexander Høglund
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4843 (2019)
Volume 20
Issue 19
International Journal of Molecular Sciences, Vol 20, Iss 19, p 4843 (2019)
Volume 20
Issue 19
Cysteine cathepsins are critical components of the adaptive immune system involved in the generation of epitopes for presentation on human leukocyte antigen (HLA) molecules and have been implicated in degradation of autoantigens. Immunoglobulin varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14db0cb0c80dca5a56e26dae69e00fd2
http://hdl.handle.net/10852/75268
http://hdl.handle.net/10852/75268