Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Run-Sheng Ruan"'
Publikováno v:
Oncotarget
Non-small cell lung cancer (NSCLC) patients with activating epidermal growth factor receptor (EGFR) mutations initially respond well to the EGFR tyrosine kinase inhibitors (TKIs) erlotinib and gefitinib. However, clinical efficacy is limited by the d
Publikováno v:
Cancer immunology, immunotherapy : CII. 67(6)
It is now recognized that solid tumors encroach on the host’s immune microenvironment to favor its own proliferation. Strategies to enhance the specificity of the endogenous T-cell population against tumors have been met with limited clinical succe
Autor:
Chi-Meng Tzeng, Run-Sheng Ruan, Qing Lin, Wen-Qing Huang, Zhongxian Lu, Xuan Zhuang, Liang-Liang Cai
Publikováno v:
Current Cancer Drug Targets. 14:567-588
Src homology 2 (SH2)-containing protein tyrosine phosphatase 2 (SHP2), encoded by the human PTPN11 gene, is a ubiquitously expressed protein tyrosine phosphatase (PTP) that consists of two tandem Src homology (SH2) domains (N-SH2 and C-SH2), a PTP ca
Autor:
Run-Sheng Ruan
Publikováno v:
International Congress Series. 1240:1125-1128
Publikováno v:
Virchows Archiv. 441:444-448
Somatostatin receptors (SS-Rs) are expressed in neuroendocrine tumour tissues where they can be targetted for diagnosis and therapy. This study investigated the presence of SS-Rs in nasopharyngeal carcinoma (NPC), a common cancer in South-East Asia.
Publikováno v:
Annals of the New York Academy of Sciences. 962:161-181
Whether nitric oxide is cytodestructive or cytoprotective is of obvious clinical importance. The debate on this subject in the past decade has generated much “heat and light”. This paper focuses on the actions of NO on the nervous system and reex
Publikováno v:
Current drug targets. 15(10)
Neuro-hormonal regulation of cardiac function via cathecol-amines results in increased heart rate and contractility. A persistent adrenergic tone, however, is an insult to the heart, affecting its regular homeostasis, altering morphology and gene exp
Publikováno v:
Experimental Neurology. 158:192-201
Sodium nitroprusside (SNP) has been used as a donor for nitric oxide (NO) to study the effects of NO on the mammalian cochlea. In the present study, we set out to determine whether NO was the chemical responsible for the ototoxic effects seen after t
Publikováno v:
Hearing Research. 114:169-178
Nitric oxide (NO) not only has normal physiological roles like vasodilation and neurotransmission in the living organism, it could also have possible neurodestructive effects under certain pathological conditions. The present study aimed to determine
Autor:
Run-Sheng, Ruan, Ke-Cheng, Xu
Publikováno v:
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 33(12)