Výsledky vyhledávání - "Run-Run Zhou"

Synthesis and structure–activity relationship of N-(piperidin-4-yl)benzamide derivatives as activators of hypoxia-inducible factor 1 pathways

Autor: Run-Run Zhou, Li Shanhua, Liang Han, Ning Qu, Fu-Nan Li, Wang Baorui, Hong Qiao, Zhi-Ning Huang, Hua Li, Li-Juan Wang

Publikováno v: Archives of Pharmacal Research. 41:1149-1161

Guided by bioisosterism and pharmacokinetic parameters, we designed and synthesized a series of novel benzamide derivatives. Preliminary in vitro studies indicated that compounds 10b and 10j show significant inhibitory bioactivity in HepG2 cells (IC5

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a346729d68f77b6ba9734ef6ee33467f
https://doi.org/10.1007/s12272-018-1050-2

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