Výsledky vyhledávání - "Run-Qing Xue"

Acetylcholine reduces palmitate-induced cardiomyocyte apoptosis by promoting lipid droplet lipolysis and perilipin 5-mediated lipid droplet-mitochondria interaction

Autor: Ming Zhao, Run-Qing Xue, Qing Wu, Dong-Ling Li, Wei-Jin Zang, Xi He, Xiao-Jiang Yu, Shengpeng Wang

Publikováno v: Cell Cycle

Lipid droplets (LDs), which are neutral lipid storage organelles, are important for lipid metabolism and energy homeostasis. LD lipolysis and interactions with mitochondria are tightly coupled to cellular metabolism and may be potential targets to bu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443fe125974420bd9230d9efb4c6a36e
https://doi.org/10.1080/15384101.2021.1965734

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Pyridostigmine alleviates cardiac dysfunction via improving mitochondrial cristae shape in a mouse model of metabolic syndrome

Autor: Ming Zhao, Xiao-Jiang Yu, Wei-Jin Zang, Si Yang, Run-Qing Xue, Qing Wu, Dong-Ling Li, Yan-Ling Cui, Man Xu

Publikováno v: Free Radical Biology and Medicine. 134:119-132

Insulin resistance and autonomic imbalance are important pathological processes in metabolic syndrome-induced cardiac remodeling. Recent studies determined that disruption of mitochondrial cristae shape is associated with myocardial ischemia; however

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28584249e13b9c0f71b62ed8492670a9
https://doi.org/10.1016/j.freeradbiomed.2019.01.011

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[Recent progress on obesity-induced myocardial remodeling and its possible mechanism of mitochondrial dyshomeostasis]

Autor: Qing, Wu, Run-Qing, Xue, Man, Xu, Yi, Lu, Xiao-Jiang, Yu, Long-Zhu, Liu, Wei-Jin, Zang

Publikováno v: Sheng li xue bao : [Acta physiologica Sinica]. 71(2)

Obesity is an important risk factor for cardiovascular diseases, which can lead to a variety of cardiovascular diseases including myocardial remodeling. Obesity may induce myocardial dysfunction by affecting hemodynamics, inducing autonomic imbalance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::95185110b48c2abeffee4ad5866f89d7
https://pubmed.ncbi.nlm.nih.gov/31008481

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Vagal nerve stimulation improves mitochondrial dynamicsviaan M3receptor/CaMKKβ/AMPK pathway in isoproterenol-induced myocardial ischaemia

Autor: Wei-Jin Zang, Run-Qing Xue, Xiao-Jiang Yu, Lei Sun, Dong-Ling Li

Publikováno v: Journal of Cellular and Molecular Medicine

Mitochondrial dynamics—fission and fusion—are associated with ischaemic heart disease (IHD). This study explored the protective effect of vagal nerve stimulation (VNS) against isoproterenol (ISO)‐induced myocardial ischaemia in a rat model and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54371d03cca893a1b890fb5c1bed61de
https://doi.org/10.1111/jcmm.12938

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Choline ameliorates cardiac hypertrophy by regulating metabolic remodelling and UPRmt through SIRT3-AMPK pathway

Autor: Ming Zhao, Wei-Jin Zang, Run-Qing Xue, Qing Wu, Xiao-Jiang Yu, Xiao-Ting Zuo, Su-Yun Yong, Man Xu, Yan-Ling Cui, Yi Lu

Publikováno v: Cardiovascular research. 115(3)

Aims Cardiac hypertrophy is characterized by a shift in metabolic substrate utilization, but the molecular events underlying the metabolic remodelling remain poorly understood. We explored metabolic remodelling and mitochondrial dysfunction in cardia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c6e5f3aa45255149b62d7734eb5088
https://pubmed.ncbi.nlm.nih.gov/30165480

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Acetylcholine Attenuates Hypoxia/Reoxygenation Injury by Inducing Mitophagy Through PINK1/Parkin Signal Pathway in H9c2 Cells

Autor: Mei Zhao, Run-Qing Xue, Yang Yang, Jiankang Liu, Xiao-Jiang Yu, Wei-Jin Zang, Lei Sun

Publikováno v: Journal of Cellular Physiology. 231:1171-1181

Acetylcholine (ACh) protected against cardiac injury via promoting autophagy and mitochondrial biogenesis, however, the involvement of mitophagy in ACh-elicited cardioprotection remains unknown. In the present study, H9c2 cardiomyocytes were subjecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a15634aa4cd9dd8f641e8c0b0a1f5e58
https://doi.org/10.1002/jcp.25215

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[Recent progress of mitochondrial quality control in ischemic heart disease and its role in cardio-protection of vagal nerve]

Autor: Run-Qing, Xue, Man, Xu, Xiao-Jiang, Yu, Long-Zhu, Liu, Wei-Jin, Zang

Publikováno v: Sheng li xue bao : [Acta physiologica Sinica]. 69(5)

Ischemic heart disease (IHD) is the life-threatening cardiovascular disease. Mitochondria have emerged as key participants and regulators of cellular energy demands and signal transduction. Mitochondrial quality is controlled by a number of coordinat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5695bb797db9c2ec2e253ca55d63c96d
https://pubmed.ncbi.nlm.nih.gov/29063106

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Choline ameliorates cardiovascular damage by improving vagal activity and inhibiting the inflammatory response in spontaneously hypertensive rats

Autor: Long-Zhu Liu, Xiao-Jiang Yu, Run-Qing Xue, Yi Lu, Wei-Jin Zang, Xi He, Xue-Yuan Bi, Man Xu

Publikováno v: Scientific Reports

Autonomic dysfunction and abnormal immunity lead to systemic inflammatory responses, which result in cardiovascular damage in hypertension. The aim of this report was to investigate the effects of choline on cardiovascular damage in hypertension. Eig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262bcb080942e4d7b98232ddb6c2174c

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