Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Run-Lei Du"'
Autor:
Shang-Ze Li, Qi-Peng Shu, Hai-Meng Zhou, Yu-Ying Liu, Meng-Qi Fan, Xin-Yi Liang, Lin-Zhi Qi, Ya-Nan He, Xue-Yi Liu, Xue-Hua Du, Xi-Chen Huang, Yu-Zhen Chen, Run-Lei Du, Yue-Xiu Liang, Xiao-Dong Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Activation of the NF-κB pathway is strictly regulated to prevent excessive inflammatory and immune responses. In a well-known negative feedback model, IκBα-dependent NF-κB termination is a delayed response pattern in the later stage of a
Externí odkaz:
https://doaj.org/article/3f826d23a77e4eae86987c5233015fc0
Autor:
Tao Liu, Meng-Qi Fan, Xiao-Xiao Xie, Qi-Peng Shu, Xue-Hua Du, Lin-Zhi Qi, Xiao-Dong Zhang, Ming-Hui Zhang, Guang Shan, Run-Lei Du, Shang-Ze Li
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background The catenin beta 1 gene (CTNNB1) plays a crucial role in the malignant progression of various cancers. Recent studies have suggested that CTNNB1 hyperactivation is closely related to the occurrence and development of bladder cance
Externí odkaz:
https://doaj.org/article/77b0d8d306b94929b2993eeac723798f
Autor:
Xue-Hua Du, Shao-Bo Ke, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li
Publikováno v:
Cell Death and Disease, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract MAPK/JNK signaling is pivotal in carcinogenesis. However, ubiquitin-mediated homeostasis of JNK remains to be verified. Here, with results from RNA sequencing (RNA-seq) and luciferase reporter pathway identification, we show that USP14 orche
Externí odkaz:
https://doaj.org/article/64d441ce684b492e95fb7c970c2bd7e1
Autor:
Shang-Ze Li, Ze-Yan Zhang, Jie Chen, Ming-You Dong, Xue-Hua Du, Jie Gao, Qi-Peng Shu, Chao Li, Xin-Yi Liang, Zhi-Hao Ding, Run-Lei Du, Junli Wang, Xiao-Dong Zhang
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Serum response factor (SRF) regulates differentiation and proliferation by binding to RhoA-actin-activated MKL or Ras-MAPK-activated ELK transcriptional coactivators, but the molecular mechanisms responsible for SRF regulation remain unclear
Externí odkaz:
https://doaj.org/article/f9f2d59e373445dfa84580f40a5d36f6
Autor:
Chao Li, Shang-Ze Li, Xi-Cheng Huang, Jie Chen, Wenbin Liu, Xiao-Dong Zhang, Xue-Min Song, Run-Lei Du
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 838-848 (2021)
Protein tyrosine phosphatase non-receptor type 18 (PTPN18) is often highly expressed in colorectal cancer (CRC), but its role in this disease remains unclear. We demonstrated that PTPN18 overexpression promotes growth and tumorigenesis in CRC cells a
Externí odkaz:
https://doaj.org/article/fc40637f1de347f19d95715d00d606a3
Autor:
Xin-Yi Liang, Yue Zhang, Ya-Nan He, Xue-Yi Liu, Zhi-Hao Ding, Xiao-Dong Zhang, Ming-You Dong, Run-Lei Du
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Hepatocellular carcinoma (HCC) is the most prevalent type of primary liver cancer characterized by high mortality and morbidity rate. The lack of effective treatments and the high frequency of recurrence lead to poor prognosis of patients with HCC. T
Externí odkaz:
https://doaj.org/article/6035b20ee4434d22897354753d2463c4
Autor:
Shang-Ze Li, Qi-Peng Shu, Yang Song, Hui-Hui Zhang, Yi Liu, Bing-Xue Jin, Tian-Zi Liuyu, Chao Li, Xi-Chen Huang, Run-Lei Du, Wei Song, Bo Zhong, Xiao-Dong Zhang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The Nemo-like kinase (NLK) plays a regulatory role in immune responses. Here, the authors show that NLK inhibits antiviral IFN responses by phosphorylating the mitochondrial antiviral-signaling protein MAVS and describe a MAVS-derived peptide that ex
Externí odkaz:
https://doaj.org/article/ff479f2686d243949b20b20a1875edd4
Publikováno v:
Functional & Integrative Genomics; Apr2024, Vol. 24 Issue 2, p1-15, 15p
Autor:
Xi-Cheng Huang, Xue-Min Song, Shang-Ze Li, Run-Lei Du, Jie Chen, Xiao-Dong Zhang, Wenbin Liu, Li Chao
Publikováno v:
Genes & Diseases
Genes and Diseases, Vol 8, Iss 6, Pp 838-848 (2021)
Genes and Diseases, Vol 8, Iss 6, Pp 838-848 (2021)
Protein tyrosine phosphatase non-receptor type 18 (PTPN18) is often highly expressed in colorectal cancer (CRC), but its role in this disease remains unclear. We demonstrated that PTPN18 overexpression promotes growth and tumorigenesis in CRC cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78598f0017f5d4f92bbbc81ecfad36a3
https://doi.org/10.1016/j.gendis.2020.08.001
https://doi.org/10.1016/j.gendis.2020.08.001
Autor:
Xue-Hua Du, Shao-Bo Ke, Xin-Yi Liang, Jie Gao, Xiao-Xiao Xie, Lin-Zhi Qi, Xue-Yi Liu, Guo-Yuan Xu, Xiao-Dong Zhang, Run-Lei Du, Shang-Ze Li
MAPK/JNK signaling is pivotal in carcinogenesis. However, ubiquitin-mediated homeostasis of JNK remains to be verified. Here, with results from RNA sequencing (RNA-seq) and luciferase reporter pathway identification, we show that USP14 orchestrates M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da471b426d1531b8933d4a93d57552a5
https://doi.org/10.21203/rs.3.rs-1702021/v1
https://doi.org/10.21203/rs.3.rs-1702021/v1
