Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Run Zhen Zhao"'
Publikováno v:
World J Stem Cells
Respiratory diseases, including coronavirus disease 2019 and chronic obstructive pulmonary disease (COPD), are leading causes of global fatality. There are no effective and curative treatments, but supportive care only. Cell therapy is a promising th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1579a413cbaf43972a7cfe3792aa1299
https://pubmed.ncbi.nlm.nih.gov/32742564
https://pubmed.ncbi.nlm.nih.gov/32742564
Publikováno v:
International Journal of Biological Sciences
Regeneration of the epithelium of mammalian lungs is essential for restoring normal function following injury, and various cells and mechanisms contribute to this regeneration and repair. Club cells, bronchioalveolar stem cells (BASCs), and alveolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0af93fd21e749f2736399dd7123d16e
https://doi.org/10.7150/ijbs.15747
https://doi.org/10.7150/ijbs.15747
Publikováno v:
Journal of Cancer
Esophageal cancer is an aggressive disease featured by early lymphatic and hematogenous dissemination, and is the sixth leading cause of cancer-related deaths worldwide. The proper formation of apicobasal polarity is essential for normal epithelium p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a824a79e5214bbf2fe05442e09600ee4
https://doi.org/10.7150/jca.11709
https://doi.org/10.7150/jca.11709
Autor:
Run Zhen Zhao, Andrew Lee, Yao Huang, Xue Feng Su, Yongchang Chang, Sadis Matalon, Hong Guang Nie, Hong Long Ji, Dong Yun Han
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology
Salt absorption via apical epithelial sodium channels (ENaC) is a critical rate-limiting process in maintaining airway and lung lining fluid at the physiological level. δ ENaC (termed δ1 in this article) has been detected in human lung epithelial c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f1299bc31581c262f4a13a3eba09ad
https://doi.org/10.1152/ajplung.00331.2011
https://doi.org/10.1152/ajplung.00331.2011
Autor:
Run Zhen Zhao, Raul Molina, Yongchang Chang, Gretta M. Sharp, Hong Long Ji, Dong Yun Han, Meimi Zhao, Xue Feng Su
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1808:1818-1826
External Na(+) self-inhibition is an intrinsic feature of epithelial sodium channels (ENaC). Cpt-cAMP regulates heterologous guinea pig but not rat αβγ ENaC in a ligand-gated manner. We hypothesized that cpt-cAMP may eliminate the self-inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a146ccd7fc4ddfc2f9a92a4a0c977151
https://doi.org/10.1016/j.bbamem.2011.03.004
https://doi.org/10.1016/j.bbamem.2011.03.004
The fourth subunit of the epithelial sodium channel, termed delta subunit (δ ENaC), was cloned in human and monkey. Increasing evidence shows that this unique subunit and its splice variants exhibit biophysical and pharmacological properties that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b0c3f2bf0bf58b7f7126385948abaae
https://europepmc.org/articles/PMC3532584/
https://europepmc.org/articles/PMC3532584/
Autor:
Hong Long Ji, Xue Mei Shi, Hong Guang Nie, Xue Feng Su, Dong Yun Han, Run Zhen Zhao, Deepa Bhattarai, Katlin Landers, Hua Tang, Meimi Zhao, Lin Zhang
Publikováno v:
American journal of respiratory cell and molecular biology. 45(5)
Salt absorption via alveolar epithelial Na(+) channels (ENaC) is a critical step for maintaining an airspace free of flooding. Previously, we found that 8-(4-chlorophenylthio)-guanosine-3',5'-cyclic monophosphate-Na (CPT-cGMP) activated native and he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164c9927eb1f04830ed6cc8b7200fb07
https://pubmed.ncbi.nlm.nih.gov/21562313
https://pubmed.ncbi.nlm.nih.gov/21562313
Autor:
Ji-Bin Peng, Hong Long Ji, Hong Guang Nie, Qing Nan Li, Wei Zhang, Dong Yun Han, Xue Feng Su, Run Zhen Zhao, Jun Li
Publikováno v:
American Journal of Physiology-Renal Physiology
Epithelial sodium channels (ENaC) are regulated by protein kinase A, in addition to a broad spectrum of other protein kinases. It is not clear whether cGMP/PKG signaling might regulate ENaC activity. We examined the responses of αβγ-ENaC channels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ac4019b357802756cd51fe2ac07c33e
https://europepmc.org/articles/PMC2822513/
https://europepmc.org/articles/PMC2822513/
Publikováno v:
American Journal of Physiology: Lung Cellular & Molecular Physiology; Dec2012 Part2, Vol. 47 Issue 6, pL1013-L1026, 14p
Autor:
Dong-Yun Han, Hong-Guang Nie, Xue-Feng Su, Xue-Mei Shi, Bhattarai, Deepa, Meimi Zhao, Run-Zhen Zhao, Landers, Katlin, Hua Tang, Lin Zhang, Hong-Long Ji
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; 2011, Vol. 45 Issue 5, following p1007-1014, 11p, 1 Color Photograph, 6 Graphs