Gelatin-based membrane containing usnic acid-loaded liposomes: A new treatment strategy for corneal healing

Autor: Flavia Rodrigues da Silva, Rummenigge Oliveira Silva, Hortência Maciel de Castro Oliveira, Lays Fernanda Nunes Dourado, Bruna Lopes da Costa, Bruno Santos Lima, Nayara Gomes Lima Santos, Carlos Eduardo Palanch Repeke, Gustavo Batista Menezes, Adriano Antunes de Souza Araújo, Armando da Silva-Cunha, Paula Santos Nunes

Publikováno v: Biomedicine & Pharmacotherapy, Vol 130, Iss , Pp 110391- (2020)

Purpose: To evaluate the safety and potential healing efficacy of the topical ocular administration of a gelatin membrane containing usnic acid/liposomes (UALs) for corneal cicatrization. UALs have shown healing activity in animal models of dermal bu

Externí odkaz: https://doaj.org/article/67403c9f6b61495284056df090519cbe

A New Topical Eye Drop Containing LyeTxI-b, A Synthetic Peptide Designed from A Lycosa erithrognata Venom Toxin, Was Effective to Treat Resistant Bacterial Keratitis

Autor: Carolina Nunes da Silva, Flavia Rodrigues da Silva, Lays Fernanda Nunes Dourado, Pablo Victor Mendes dos Reis, Rummenigge Oliveira Silva, Bruna Lopes da Costa, Paula Santos Nunes, Flávio Almeida Amaral, Vera Lúcia dos Santos, Maria Elena de Lima, Armando da Silva Cunha Júnior

Publikováno v: Toxins, Vol 11, Iss 4, p 203 (2019)

Bacterial keratitis is an ocular infection that can lead to severe visual disability. Staphylococcus aureus is a major pathogen of the eye. We recently demonstrated the strong antimicrobial activity of LyeTxI-b, a synthetic peptide derived from a Lyc

Externí odkaz: https://doaj.org/article/d2a64209a9f44c8091729647f44cc2f6

The proteolytic fraction from Vasconcellea cundinamarcensis accelerates wound healing after corneal chemical burn in rabbits

Autor: Carlos E. Salas, Alfredo M. Goes, Flavia Rodrigues da Silva, Miriam Teresa Paz Lopes, Thaís Maria da Mata Martins, Bruna Lopes da Costa, Rummenigge Oliveira Silva, Lays Fernanda Nunes Dourado, Carolina Nunes da Silva, Armando Silva-Cunha

Publikováno v: Burns. 46:928-936

Introduction Chemical ocular burns are among the most frequently eye-related injuries, which require immediate and intensive evaluation and care since they may lead to potential complications such as superinfection, corneal perforation, and blindness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc10ea31941d26979591e0958c77fd0f
https://doi.org/10.1016/j.burns.2019.10.005

Four modified sodium alginate/carboxymethylcellulose blends for prednisone delivery

Autor: Kláudia Maria Machado Neves Silva, Priscila Pereira Silva-Caldeira, Armando Silva-Cunha, Rummenigge Oliveira Silva, Lays Fernanda Nunes Dourado, Juan Carlos Campos Rubio, Rodrigo R. Resende, Anderson K. Santos, Paulo Eustáquio de Faria, Bruna Lopes da Costa, Gisele Assis Castro Goulart

Publikováno v: Journal of Applied Polymer Science. 138:50383

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::22d8555608d3a4115b4f5a859185495f
https://doi.org/10.1002/app.50383

Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorioallantoic membrane model

Autor: Lays Fernanda Nunes Dourado, Armando Silva-Cunha, Bruna Lopes da Costa, Maria Elena de Lima, Rummenigge Oliveira Silva, Carolina Nunes da Silva, Cibele Rodrigues Toledo, Mayara Rodrigues Brandão de Paiva, Flavia Rodrigues da Silva

Publikováno v: Journal of Venomous Animals and Toxins including Tropical Diseases v.24 2018
The Journal of venomous animals and toxins including tropical diseases
Universidade Estadual Paulista (UNESP)
instacron:UNESP
The Journal of Venomous Animals and Toxins Including Tropical Diseases
Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 24, Article number: 31, Published: 17 DEC 2018
Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 24, Iss 1, Pp 1-13 (2018)

Background: The great diversity of molecules found in spider venoms include amino acids, polyamines, proteins and peptides, among others. Some of these compounds can interact with different neuronal receptors and ion channels including those present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de2b2c3b079830fdd1e043024eb953d
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992018000100322