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Akademický článek

2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice.

Autor: Hirofumi Morihara, Masanori Obana, Shota Tanaka, Ikki Kawakatsu, Daisuke Tsuchiyama, Shota Mori, Hiroshi Suizu, Akiko Ishida, Rumi Kimura, Izuru Tsuchimochi, Makiko Maeda, Takehiko Yoshimitsu, Yasushi Fujio, Hiroyuki Nakayama

Publikováno v: PLoS ONE, Vol 12, Iss 12, p e0189948 (2017)

Excessive levels of reactive oxygen species (ROS) and impaired Ca2+ homeostasis play central roles in the development of multiple cardiac pathologies, including cell death during ischemia-reperfusion (I/R) injury. In several organs, treatment with 2-

Externí odkaz: https://doaj.org/article/7621d1ec32c54fc198e89394bb5cc0dd

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2-aminoethoxydiphenyl borate provides an anti-oxidative effect and mediates cardioprotection during ischemia reperfusion in mice

Autor: Izuru Tsuchimochi, Masanori Obana, Makiko Maeda, Rumi Kimura, Takehiko Yoshimitsu, Hiroshi Suizu, Shota Mori, Hiroyuki Nakayama, Daisuke Tsuchiyama, Ikki Kawakatsu, Hirofumi Morihara, Yasushi Fujio, Shota Tanaka, Akiko Ishida

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 12, p e0189948 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2356102ecd25a0c83396909e55d67f25
https://pubmed.ncbi.nlm.nih.gov/29267336

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Dad1 inhibits cardiomyocyte death by promoting cell adhesion

Autor: Shota Fuchigami, Rumi Kimura, Mori Shota, Makiko Maeda, Kotaro Matsumoto, Masanori Obana, Yasushi Fujio

Publikováno v: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:3-O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a95b6e3ff0663717d0fd2c1dce9d3f8b
https://doi.org/10.1254/jpssuppl.93.0_3-o-131

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Suppression of Defender against cell death 1 leads to cardiomyocyte death

Autor: Shota Mori, Yasushi Fujio, Hirofumi Morihara, Shota Fuchigami, Kotaro Matumoto, Rumi Kimura, Masonori Obana, Hiroyuki Nakayama, Makiko Maeda

Publikováno v: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 92:3-O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::12a7f27211e96c8f15892856faf074e0
https://doi.org/10.1254/jpssuppl.92.0_3-o-26

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A new synthetic method for the preparation of α,β-didehydroamino acid derivatives by means of a wittig-type reaction. Syntheses of (2S, 4S)- and (2R, 4R)-4-hydroxyprolines

Autor: Rumi Kimura, Hideki Kinoshita, Tanemasa Nagano

Publikováno v: Bulletin of the Chemical Society of Japan. 75(11):2517-2525

Ethyl N-Boc- and N-Z-α-tosylglycinates were reacted with a variety of aldehydes in the presence of tributylphosphine and a base to afford the corresponding α,β-didehydroamino acid derivatives with high (Z)-selectivity in good yields. Moreover, eth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5eb3efb3e1d88d2c4fcef0efdbaaa4b
http://hdl.handle.net/2297/38276

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ChemInform Abstract: Stereoselective Syntheses of (E)-α,β-Didehydroamino Acid and Peptide Containing Its Residue Utilizing Oxazolidinone Derivative

Autor: Rumi Kimura, Miki Kometani, Kohki Ihara, Hideki Kinoshita

Publikováno v: ChemInform. 40

Reaction of methyl N-Boc-N-phenoxycarbonylglycinate with various aldehydes afforded the corresponding cis-4,5-oxazolidinone derivatives, which were effectively converted to (E)-α,β-didehydroamino a...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e59aae63ea65e87e35a2005f6655c373
https://doi.org/10.1002/chin.200929190

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