Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rumi Igarashi"'
Autor:
Yoshikazu Ganchiku, Nozomi Kobayashi, Ryoichi Goto, Ryo Kanazawa, Kazuaki Shibuya, Masaaki Watanabe, Norio Kawamura, Rumi Igarashi, Akinobu Taketomi, Masaaki Zaitsu, Yasutomo Fukasaku, Takuji Ota
Publikováno v:
Transplant international : official journal of the European Society for Organ TransplantationReferences. 34(12)
Immunological behavior of graft-infiltrating lymphocytes (GILs) determines the graft fate (i.e., rejection or acceptance). Nevertheless, the functional alloreactivity and the phenotype of GILs at various times during the early post-transplantation ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eabe08428f30e14a0860896bcab0a07
https://pubmed.ncbi.nlm.nih.gov/34687578
https://pubmed.ncbi.nlm.nih.gov/34687578
Autor:
Shin, Emoto, Susumu, Shibasaki, Akihisa, Nagatsu, Ryoichi, Goto, Hitoshi, Ono, Yasutomo, Fukasaku, Rumi, Igarashi, Takuji, Ota, Moto, Fukai, Tsuyoshi, Shimamura, Kan, Saiga, Akinobu, Taketomi, Masaaki, Murakami, Satoru, Todo, Kenichiro, Yamashita
Publikováno v:
Transplant immunology. 65
We have previously demonstrated the unique properties of a new triazolopyrimidine derivative, NK026680, which exerts immunosuppressive effects in rat heart transplant model and confers tolerogeneic properties on ex vivo-conditioned dendritic cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f53fabf23c103f663b680c2995f8eaa4
https://pubmed.ncbi.nlm.nih.gov/33022372
https://pubmed.ncbi.nlm.nih.gov/33022372
Autor:
Satoru Todo, Moto Fukai, Rumi Igarashi, Hitoshi Ono, Takuji Ota, Akihisa Nagatsu, Kan Saiga, Yasutomo Fukasaku, Kenichiro Yamashita, Akinobu Taketomi, Susumu Shibasaki, Ryoichi Goto, Masaaki Murakami, Tsuyoshi Shimamura, Shin Emoto
Publikováno v:
Transplant Immunology. 65:101338
We have previously demonstrated the unique properties of a new triazolopyrimidine derivative, NK026680, which exerts immunosuppressive effects in rat heart transplant model and confers tolerogeneic properties on ex vivo-conditioned dendritic cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5771e428ed8b4bf9c781c6cab48efce9
https://doi.org/10.1016/j.trim.2020.101338
https://doi.org/10.1016/j.trim.2020.101338
Autor:
Rumi Igarashi, Satoru Todo, Nozomi Kobayashi, Susumu Shibasaki, Kazuo Umezawa, M. Ogura, Tadashi Yoshida, Moto Fukai, Kenichiro Yamashita, Y. Tsunetoshi, Masaaki Zaitsu
Publikováno v:
Transplantation. 99:948-956
Graft arterial disease (GAD) is a major cause of late graft loss after organ transplantation. Alloimmune responses and vascular remodeling eventually cause the transplant organ to develop GAD. In this study, we aimed to limit the development of GAD b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf893fe6bd7ebef4557cbb5d0f3b7cc
https://doi.org/10.1097/tp.0000000000000576
https://doi.org/10.1097/tp.0000000000000576
Autor:
Michitaka Ozaki, Ryoichi Goto, Rumi Igarashi, Kenichiro Yamashita, Susumu Shibasaki, Sanae Haga, Gentaro Hirokata, Y. Tsunetoshi, Masaaki Zaitsu, Kenji Wakayama, Yoshiki Yanagawa, Satoru Todo
Publikováno v:
Transplantation. 93:1229-1237
Background Pharmacologically modulated dendritic cells (DCs) can potentially regulate alloimmune responses. We examined the characteristics of immunoregulatory DCs induced by a novel triazolopyrimidine derivative, NK026680, which has been previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17bbd7c82dcc9221032ae053938bc11
https://doi.org/10.1097/tp.0b013e3182516c9f
https://doi.org/10.1097/tp.0b013e3182516c9f
Autor:
Keita Terui, Michitaka Ozaki, Rumi Igarashi, Sanae Haga, Shizuo Akira, Satoru Todo, Wataru Ogawa, Tetsuya Ogino, Hiroyuki Furukawa, Kiyoshi Takeda, Hiroshi Inoue, Shin Enosawa
Publikováno v:
Journal of Hepatology. 43:799-807
Background/aims Liver regeneration following hepatectomy is complicated and involves a variety of interacting factors. The present study was designed to study the roles of proliferation and hypertrophy of hepatocytes in liver regeneration following h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daae7ecb3fde5063cfded246d4cc2cf8
https://doi.org/10.1016/j.jhep.2005.03.027
https://doi.org/10.1016/j.jhep.2005.03.027
Autor:
Satoru Todo, Rumi Igarashi, Ryoichi Goto, Kazuo Umezawa, Kenji Wakayama, Michitaka Ozaki, Kenichiro Yamashita, Y. Tsunetoshi, Masaaki Zaitsu, Susumu Shibasaki, Sanae Haga
Publikováno v:
Transplantation. 95(4)
BACKGROUND A newly developed compound, 3-[(dodecylthiocarbonyl)methyl]-glutarimide (DTCM-G), has been shown to inhibit nuclear translocation of c-Fos/c-Jun in a murine macrophage cell line. Herein, we studied the immunosuppressive properties and pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e00287e3162e4661c445d444232722
https://pubmed.ncbi.nlm.nih.gov/23269193
https://pubmed.ncbi.nlm.nih.gov/23269193
Autor:
Nozomi Kobayashi, Ryoichi Goto, Rumi Igarashi, Kenichiro Yamashita, Motohiro Uno, Tomohiro Shibata, Shinya Ueki, Kazuo Umezawa, Michitaka Ozaki, Masaaki Zaitsu, Takeshi Aoyagi, Satoru Todo, Susumu Shibasaki, Tetsu Oura, Kenji Wakayama, Gentaro Hirokata
Publikováno v:
Transplantation. 93(8)
Background Nuclear factor-κB (NF-κB) is a key molecule in alloimmune responses, however, its role in tolerance induction is not clear. We have previously reported that dehydroxymethylepoxyquinomycin (DHMEQ), a novel NF-κB inhibitor, prolongs cardi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0738bf772f46f623a13a7c3065c708
https://pubmed.ncbi.nlm.nih.gov/22357176
https://pubmed.ncbi.nlm.nih.gov/22357176
Autor:
Sanae Haga, Michitaka Ozaki, Gentaro Hirokata, Rumi Igarashi, Susumu Shibasaki, Kenichiro Yamashita, Tetsu Oura, Ryoichi Goto, Tomohiro Shibata, Kenji Wakayama, Satoru Todo
Publikováno v:
Transplant immunology. 26(1)
NK026680 is a triazolopyrimidine derivative that has been shown to inhibit dendritic cell maturation and activation. Here, we examined the immunosuppressive properties of NK026680 on T-cell function and assessed its immunosuppressive efficacy in an A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7313c4e6f1a3d24e5baa10d43be01233
https://pubmed.ncbi.nlm.nih.gov/22019622
https://pubmed.ncbi.nlm.nih.gov/22019622
Autor:
K. Saiga, Ryoichi Goto, Susumu Shibasaki, Rumi Igarashi, Akihisa Nagatsu, Shin Emoto, S. Todo, Takeshi Aoyagi, Akinobu Taketomi, Hitoshi Ono, Kenichiro Yamashita, Tsuyoshi Shimamura, Moto Fukai
Publikováno v:
Transplantation. 98:285-286
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f6d6e00344a96966e9edb76bd487d44a
https://doi.org/10.1097/00007890-201407151-00886
https://doi.org/10.1097/00007890-201407151-00886