Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Rumana Mowla"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2089
Antimicrobial resistance (AMR) is rapidly becoming one of the great healthcare challenges. A common mechanism employed by pathogenic bacteria to avoid the action of certain antibiotics is to overexpress efflux pumps that can extrude these drugs from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7c817565802cae8397922feed01c5d87
https://pubmed.ncbi.nlm.nih.gov/31773650
https://pubmed.ncbi.nlm.nih.gov/31773650
Publikováno v:
Methods in Molecular Biology ISBN: 9781071601624
Antimicrobial resistance (AMR) is rapidly becoming one of the great healthcare challenges. A common mechanism employed by pathogenic bacteria to avoid the action of certain antibiotics is to overexpress efflux pumps that can extrude these drugs from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef0081fe3fa7f1cec49ecbb64ac6442
https://doi.org/10.1007/978-1-0716-0163-1_7
https://doi.org/10.1007/978-1-0716-0163-1_7
Autor:
Henrietta Venter, Di Song, Rumana Mowla, Yuetai Teng, Rawaf Alenzy, Steven W. Polyak, Yinhu Wang, Xingbang Liu, Yingang Ma, Shutao Ma
Publikováno v:
European journal of medicinal chemistry. 186
usc Drug efflux pumps confer multidrug resistance to dangerous bacterial pathogens which makes these proteins promising drug targets. Herein, we present initial chemical optimization and structure-activity relationship (SAR) data around a previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cc0c7a5136cbcdf287b39d89b66758
https://pubmed.ncbi.nlm.nih.gov/31801655
https://pubmed.ncbi.nlm.nih.gov/31801655
Autor:
Xinjie Gu, Chaobin Jin, Steven W. Polyak, Natansh D. Modi, Shutao Ma, Rawaf Alenazy, Yinhui Qin, Jin Quan Eugene Tan, Rumana Mowla, Henrietta Venter, Yinhu Wang
A series of novel 5-methoxy-2,3-naphthalimide derivatives were designed, synthesized and evaluated for their biological activities. In particular, the ability of the compounds to synergize with antimicrobials, to inhibit Nile Red efflux, and to targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8b5b69cafa286ec557146100571fcb
https://hdl.handle.net/11541.2/135958
https://hdl.handle.net/11541.2/135958
Multidrug efflux protein complexes such as AcrAB-TolC from Escherichia coli are paramount in multidrug resistance in Gram-negative bacteria and are also implicated in other processes such as virulence and biofilm formation. Hence efflux pump inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925febf7644e55d76b0dee98587ca437
https://hdl.handle.net/11541.2/129008
https://hdl.handle.net/11541.2/129008
Autor:
Henrietta Venter, Shutao Ma, Shengli Ji, Chaobin Jin, Miguel de Barros Lopes, Yinhu Wang, Liwei Guo, Di Song, Rumana Mowla
Publikováno v:
European journal of medicinal chemistry. 143
A novel series of 4-substituted 2-naphthamide derivatives were designed, synthesized and evaluated for their biological activity. In particular, the ability of the compounds to potentiate the action of antibiotics, to inhibit Nile Red efflux and to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1247e913a45391afbb7902a3374ff7
https://pubmed.ncbi.nlm.nih.gov/29220791
https://pubmed.ncbi.nlm.nih.gov/29220791
Publikováno v:
MicrobiologyOpen
Drug efflux pumps confer resistance upon bacteria to a wide range of antibiotics from various classes. The expression of efflux pumps are also implicated in virulence and biofilm formation. Moreover, organisms can only acquire resistance in the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14d9293f6ab152a409ae8d6b6cc41f73
http://europepmc.org/articles/PMC4263512
http://europepmc.org/articles/PMC4263512
Autor:
Miguel de Barros Lopes, Liwei Guo, Henrietta Venter, Yinhu Wang, Taufiq Rahman, Shutao Ma, Rumana Mowla, Abiodun D. Ogunniyi
Drug efflux pumps confer multidrug resistance to dangerous pathogens which makes these pumps important drug targets. We have synthesised a novel series of compounds based on a 2-naphthamide pharmacore aimed at inhibiting the efflux pumps from Gram-ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450eaa855073fa0e73871f0bffb7e9b5
https://hdl.handle.net/11541.2/123950
https://hdl.handle.net/11541.2/123950
Autor:
Rumana Mowla, Md. Abdul Muhit, Sheikh Zahir Raihan, A. K. Azad Chowdhury, Mohammad Ahsanul Akbar, Subrata Kumar Biswas
Publikováno v:
American Journal of Plant Physiology. 7:41-46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9efa2c9239e2ca280816c893ecf854b
https://doi.org/10.3923/ajpp.2012.41.46
https://doi.org/10.3923/ajpp.2012.41.46
Autor:
Rumana Mowla, Utpal Kumar Karmakar, A. K. Azad Chowdhury, Mohammad Ahsanul Akbar, Sheikh Zahir Raihan, Subrata Kumar Biswas, Md. Abdul Muhit
Publikováno v:
International Journal of Pharmacology. 8:53-57
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbd4cb643d4d7d2dbc3352c4a0ca63f6
https://doi.org/10.3923/ijp.2012.53.57
https://doi.org/10.3923/ijp.2012.53.57