Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Ruman Rahman"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The field of bioelectronics is developing exponentially. There is now a drive to interface electronics with biology for the development of new technologies to improve our understanding of electrical forces in biology. This builds on our rece
Externí odkaz:
https://doaj.org/article/ea606d9ca9664bfe9ea74a0c26409de8
Autor:
Geoffroy Andrieux, Tonmoy Das, Michaela Griffin, Jakob Straehle, Simon M. L. Paine, Jürgen Beck, Melanie Boerries, Dieter H. Heiland, Stuart J. Smith, Ruman Rahman, Sajib Chakraborty
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-34 (2023)
Abstract Background Spatiotemporal heterogeneity originating from genomic and transcriptional variation was found to contribute to subtype switching in isocitrate dehydrogenase-1 wild-type glioblastoma (GBM) prior to and upon recurrence. Fluorescence
Externí odkaz:
https://doaj.org/article/ddc7f16df4c243c3bdd8102718b49299
Publikováno v:
Bioelectronic Medicine, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract Background Electric field therapies such as Tumor Treating Fields (TTFields) have emerged as a bioelectronic treatment for isocitrate dehydrogenase wild-type and IDH mutant grade 4 astrocytoma Glioblastoma (GBM). TTFields rely on alternating
Externí odkaz:
https://doaj.org/article/9f48a496f59f4d6093549a401cff4a1d
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The manifestation of intra- and inter-tumor heterogeneity hinders the development of ubiquitous cancer treatments, thus requiring a tailored therapy for each cancer type. Specifically, the reprogramming of cellular metabolism has been identi
Externí odkaz:
https://doaj.org/article/003d1681f59944afbe3636447c71aafe
Autor:
Andie J. Robinson, Akhil Jain, Ruman Rahman, Sidahmed Abayzeed, Richard J. M. Hague, Frankie J. Rawson
Publikováno v:
ACS Omega, Vol 6, Iss 44, Pp 29495-29505 (2021)
Externí odkaz:
https://doaj.org/article/36adcd7e997e48af800943c6318dbf56
Autor:
Fatemeh Mehradnia, Cara Moloney, Robert Cavanagh, Amanda K Pearce, Alison Ritchie, Philip Clarke, Ruman Rahman, Asmaa Ibrahim, Anna M. Grabowskab, Cameron Alexander
Publikováno v:
British Journal of Pharmacy, Vol 7, Iss 2 (2022)
The therapeutic efficacy of anticancer nanocarriers is highly dependent on their size, shape, targeting ability, and stimuli-responsiveness. Herein, we studied the in vivo therapeutic efficacy of Doxorubicin (Dox) loaded redox responsive micellar-lik
Externí odkaz:
https://doaj.org/article/6673ed1d523545a49a58a9ece6f276f8
Autor:
Bethan Morris, Lee Curtin, Andrea Hawkins-Daarud, Matthew E. Hubbard, Ruman Rahman, Stuart J. Smith, Dorothee Auer, Nhan L. Tran, Leland S. Hu, Jennifer M. Eschbacher, Kris A. Smith, Ashley Stokes, Kristin R. Swanson, Markus R. Owen
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 5, Pp 4905-4941 (2020)
Glioblastomas (GBMs) are the most aggressive primary brain tumours and have no known cure. Each individual tumour comprises multiple sub-populations of genetically-distinct cells that may respond differently to targeted therapies and may contribute t
Externí odkaz:
https://doaj.org/article/99df14c01fe5480e95f2de48de682d3f
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 599 (2023)
Metabolic reprogramming, through increased uptake of cholesterol in the form of low-density lipoproteins (LDL), is one way by which cancer cells, including high grade gliomas (HGG), maintain their rapid growth. In this study, we determined LDL recept
Externí odkaz:
https://doaj.org/article/6e7951f1179647b18bb7e902faa1bef3
Autor:
Alexandra D. Rusu, Zoe E. Cornhill, Brenda Canales Coutiño, Marcos Castellanos Uribe, Anbarasu Lourdusamy, Zsuzsa Markus, Sean T. May, Ruman Rahman, Marios Georgiou
Publikováno v:
Open Biology, Vol 11, Iss 9 (2021)
Approximately 90% of cancer-related deaths can be attributed to a tumour's ability to spread. We have identified CG7379, the fly orthologue of human ING1, as a potent invasion suppressor. ING1 is a type II tumour suppressor with well-established role
Externí odkaz:
https://doaj.org/article/ac1db539b5b844c9955fe2fded805808
Publikováno v:
Molecules, Vol 27, Iss 7, p 2049 (2022)
Background: We have previously reported that the endocannabinoid receptor inverse agonist AM630 is a potent inhibitor of isocitrade dehydrogenase-1 wild-type glioblastoma (GBM) core tumour cell proliferation. To uncover the mechanism behind the anti-
Externí odkaz:
https://doaj.org/article/b98ddec68cb444c68d4b78c340647517