Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rumaisha Shoaib"'
Autor:
Manisha Marothia, Ankita Behl, Preeti Maurya, Monika Saini, Rumaisha Shoaib, Swati Garg, Geeta Kumari, Shreeja Biswas, Akshay Munjal, Sakshi Anand, Amandeep Kaur Kahlon, Pragya Gupta, Saurav Biswas, Bidhan Goswami, Haider Thaer Abdulhameed Almuqdadi, Ipsita Pal Bhowmick, Maxim Shevtsov, Sivaprakash Ramalingam, Anand Ranganathan, Shailja Singh
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109918- (2024)
Summary: Malaria parasite invasion to host erythrocytes is mediated by multiple interactions between merozoite ligands and erythrocyte receptors that contribute toward the development of disease pathology. Here, we report a novel antigen Plasmodium p
Externí odkaz:
https://doaj.org/article/1b9eaf038955493ba63df6fb77fbaed5
Autor:
Atul, Preeti Chaudhary, Swati Gupta, Rumaisha Shoaib, Rahul Pasupureddy, Bharti Goyal, Bhumika Kumar, Om Prakash Singh, Rajnikant Dixit, Shailja Singh, Mymoona Akhter, Neera Kapoor, Veena Pande, Soumyananda Chakraborti, Kapil Vashisht, Kailash C. Pandey
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 35, Iss , Pp 67-75 (2023)
ABSTRACT: Objectives: Artemisinin (ART) resistance in Plasmodium is threatening the artemisinin combination therapies—the first line of defence against malaria. ART resistance has been established to be mediated by the Plasmodium Kelch13 (PfK13) pr
Externí odkaz:
https://doaj.org/article/1d5ae284f76c4fe2bf7d1a7b3c634252
Autor:
Ankita Behl, Rumaisha Shoaib, Fernando De Leon, Geeta Kumari, Monika Saini, Evanka Madan, Vikash Kumar, Harshita Singh, Jyoti Kumari, Preeti Maurya, Swati Garg, Prakash Chandra Mishra, Christoph Arenz, Shailja Singh
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106637- (2023)
Summary: Cold shock proteins are characterized by the presence of one or more cold shock domains that bestow them with nucleic acid binding ability. Although cold shock proteins are well characterized in bacteria, plants and humans, there is no infor
Externí odkaz:
https://doaj.org/article/525c92a21d3044c9a0ab966ae4fbe669
Publikováno v:
FEBS Open Bio, Vol 12, Iss 5, Pp 1050-1060 (2022)
Malaria is a human disease caused by eukaryotic protozoan parasites of the Plasmodium genus. Plasmodium falciparum (Pf) causes the most lethal form of human malaria and is responsible for widespread mortality worldwide. Prefoldin is a heterohexameric
Externí odkaz:
https://doaj.org/article/4622f8ba247c48a58f09bfafb0a8092e
Autor:
Malabika Chakrabarti, Nishant Joshi, Geeta Kumari, Preeti Singh, Rumaisha Shoaib, Akshay Munjal, Vikash Kumar, Ankita Behl, Mohammad Abid, Swati Garg, Sonal Gupta, Shailja Singh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Cytoskeletal structures of Apicomplexan parasites are important for parasite replication, motility, invasion to the host cell and survival. Apicortin, an Apicomplexan specific protein appears to be a crucial factor in maintaining stability o
Externí odkaz:
https://doaj.org/article/6315647a3e444a20b66d4a6609194ccf
Autor:
Prerna Joshi, Swati Garg, Shailendra Mani, Kamini Jakhar, Manisha Marothia, Rumaisha Shoaib, Shreeja Biswas, Jhalak Singhal, Ankita Behl, Amandeep Kaur Kahlon, Maxim Shevtsov, Pramod Garg, Shailja Singh, Anand Ranganathan
One of the fundamental mechanisms developed by the host to contain the highly infectious and rapidly proliferating SARS coronavirus is elevation of body temperature, a natural fallout of which is Heat Shock Protein (HSP) over-expression. Here, for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b322dd0e75e136b01e5b3b689db00d58
https://doi.org/10.1101/2023.05.05.539661
https://doi.org/10.1101/2023.05.05.539661
Autor:
Sadat Shafi, Sonal Gupta, Ravi Jain, Rumaisha Shoaib, Akshay Munjal, Preeti Maurya, Abul Kalam Najmi, Shailja Singh
Oxidative stress mediated cell death has remained the prime parasiticidal mechanism of front line anti-malarial, artemisinin (ART). The emergence of resistantPlasmodiumparasites characterized by oxidative stress management due to impaired activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b89702646851d04a318aceb00846a03b
https://doi.org/10.1101/2023.04.18.537303
https://doi.org/10.1101/2023.04.18.537303
Autor:
Ayushi Chaurasiya, Geeta Kumari, Swati Garg, Rumaisha Shoaib, Zille Anam, Nishant Joshi, Jyoti Kumari, Jhalak Singhal, Niharika Singh, Shikha Kaushik, Amandeep Kaur Kahlon, Neha Dubey, Mukesh Kumar Maurya, Pallavi Srivastava, Manisha Marothia, Prerna Joshi, Kanika Gupta, Savita Saini, Gobardhan Das, Souvik Bhattacharjee, Shailja Singh, Anand Ranganathan
Publikováno v:
Antimicrob Agents Chemother
The emergence of Plasmodium falciparum resistance raises an urgent need to find new antimalarial drugs. Here, we report the rational repurposing of the anti-hepatitis C virus drug, alisporivir, a nonimmunosuppressive analog of cyclosporin A, against
Autor:
Rumaisha Shoaib, Vikash Kumar, Swati Garg, Monika Saini, Jyoti Kumari, Preeti Maurya, Aashima Gupta, Nutan Gupta, Harshita Singh, Pritee Verma, Ravi Jain, Shreeja Biswas, Ankita Behl, Mohammad Abid, Shailja Singh
SummaryThe intraerythrocytic growth of malaria parasite is challenged by the presence of proteotoxic stress and intrinsically unstructured proteins in the cytoplasm due to formation of toxic heme during haemoglobin digestion. To overcome the unavoida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34f457f19faf65f88e4272c3dc78cf86
https://doi.org/10.1101/2022.09.17.508354
https://doi.org/10.1101/2022.09.17.508354
Autor:
Ankita Behl, Monika Saini, Fernando De Leon, Geeta Kumari, Vikash Kumar, Rumaisha Shoaib, Harshita Singh, Swati Garg, Christoph Arenz, Shailja Singh
Cold shock proteins are well characterized in bacteria, plants and humans, however there is no information on their existence and role in malaria parasite. Here, we have delineated the function of a novel cold shock protein of Plasmodium falciparum (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d845031b3ddcdc256b5e896cf8dcb83
https://doi.org/10.1101/2022.07.07.499247
https://doi.org/10.1101/2022.07.07.499247