Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ruma Raha-Chowdhury"'
Autor:
Animesh Alexander Raha, Seyedeh Deniz Ghaffari, James Henderson, Subhojit Chakraborty, Kieren Allinson, Robert P. Friedland, Anthony Holland, Shahid H. Zaman, Elizabeta B. Mukaetova-Ladinska, Ruma Raha-Chowdhury
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The liver-derived hormone hepcidin, a member of the defensin family of antimicrobial peptides, plays an important role in host defense and innate immunity due to its broad antibacterial and antiviral properties. Ferritin, an iron storage protein is o
Externí odkaz:
https://doaj.org/article/1f78d9233c494996bc71cc183ea96bca
Autor:
Animesh Alexander Raha, Anwesha Biswas, James Henderson, Subhojit Chakraborty, Anthony Holland, Robert P. Friedland, Elizabeta Mukaetova-Ladinska, Shahid Zaman, Ruma Raha-Chowdhury
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1060 (2022)
Iron accumulates in the ageing brain and in brains with neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), and Down syndrome (DS) dementia. However, the mechanisms of iron depositio
Externí odkaz:
https://doaj.org/article/47dcda057fc341f68062688ecfacae7e
Autor:
K. Sigvard Olsson, Olof Wålinder, Ulf Jansson, Maria Wilbe, Marie-Louise Bondeson, Eva-Lena Stattin, Ruma Raha-Chowdhury, Roger Williams
Publikováno v:
Hereditas, Vol 154, Iss 1, Pp 1-11 (2017)
Abstract Background Genealogy and molecular genetic studies of a Swedish river valley population resulted in a large pedigree, showing that the hereditary hemochromatosis (HH) HFE/p.C282Y mutation is inherited with other recessive disorders such as W
Externí odkaz:
https://doaj.org/article/015186d12da4480f8935b6aa4354d5c3
Autor:
Serhiy Forostyak, Oksana Forostyak, Jessica C. F. Kwok, Nataliya Romanyuk, Monika Rehorova, Jan Kriska, Govindan Dayanithi, Ruma Raha-Chowdhury, Pavla Jendelova, Miroslava Anderova, James W. Fawcett, Eva Sykova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9593 (2020)
A promising therapeutic strategy for amyotrophic lateral sclerosis (ALS) treatment is stem cell therapy. Neural progenitors derived from induced pluripotent cells (NP-iPS) might rescue or replace dying motoneurons (MNs). However, the mechanisms respo
Externí odkaz:
https://doaj.org/article/4543d7869b3143b7b39478900ec4034d
Autor:
Animesh Alexander Raha, Subhojit Chakraborty, Seyedeh Deniz Ghaffari, Ruma Raha-Chowdhury, Shahid Zaman, Jessica A. Beresford-Webb, Monika Grigorova, Anthony J. Holland, Kieren Allinson, James Henderson
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 13
Journal of Clinical Medicine, Vol 10, Iss 2909, p 2909 (2021)
Volume 10
Issue 13
Journal of Clinical Medicine, Vol 10, Iss 2909, p 2909 (2021)
Down syndrome (DS) subjects are more likely to develop the clinical features of Alzheimer's disease (AD) very early in the disease process due to the additional impact of neuroinflammation and because of activation of innate immunity. Many factors in
Autor:
Elizabeth Jones, Anthony J. Holland, Anastasia Bickerton, Romina Vuono, Ruma Raha-Chowdhury, Shahid Zaman, Animesh Alexander Raha, James Henderson, Robert Fincham, Kieren Allinson
Publikováno v:
Journal of Alzheimer's Disease
Background Genetic factors that influence Alzheimer's disease (AD) risk include mutations in TREM2 and allelic variants of Apolipoprotein E, influencing AD pathology in the general population and in Down syndrome (DS). Evidence shows that dysfunction
Publikováno v:
Current Opinion in Psychiatry
Purpose of review The COVID-19 infection results in various viral-related physical and mental health problems, joined with the long-term psychological impact of the pandemic in general. However, the accompanying neurocognitive changes remain poorly u
Autor:
Jan Kriska, Eva Syková, Nataliya Romanyuk, Oksana Forostyak, Miroslava Anderova, Pavla Jendelova, Serhiy Forostyak, Govindan Dayanithi, James W. Fawcett, Jessica C. F. Kwok, Monika Rehorova, Ruma Raha-Chowdhury
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (24), pp.9593. ⟨10.3390/ijms21249593⟩
International Journal of Molecular Sciences, Vol 21, Iss 9593, p 9593 (2020)
Volume 21
Issue 24
International Journal of Molecular Sciences, MDPI, 2020, 21 (24), pp.9593. ⟨10.3390/ijms21249593⟩
International Journal of Molecular Sciences, Vol 21, Iss 9593, p 9593 (2020)
Volume 21
Issue 24
A promising therapeutic strategy for amyotrophic lateral sclerosis (ALS) treatment is stem cell therapy. Neural progenitors derived from induced pluripotent cells (NP-iPS) might rescue or replace dying motoneurons (MNs). However, the mechanisms respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c3fccff0d4a28fc73475181963ce63
https://www.repository.cam.ac.uk/handle/1810/322512
https://www.repository.cam.ac.uk/handle/1810/322512
Autor:
Ruma Raha-Chowdhury, Animesh Alexander Raha, John Trowsdale, Elizabeta B. Mukaetova-Ladinska, Subhojit Chakraborty, James Henderson, Shahid Zaman
Publikováno v:
Bioscience Reports
Objective: In some individuals, coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leads to a variety of serious inflammatory symptoms, including blood clotting and acute respiratory distress. Death due to COVID-19 sho
Autor:
James Henderson, Romina Vuono, Robert P. Friedland, Simon R.W. Stott, Shahid Zaman, Simona Foscarin, Ruma Raha-Chowdhury, Animesh Alexander Raha
Publikováno v:
Journal of Alzheimer's Disease. 55:199-217
Neuroinflammation and activation of innate immunity are early events in neurodegenerative diseases including Alzheimer's disease (AD). Recently, a rare mutation in the gene Triggering receptor expressed on myeloid cells 2 (TREM2) has been associated