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MGF E peptide pretreatment improves the proliferation and osteogenic differentiation of BMSCs via MEK-ERK1/2 and PI3K-Akt pathway under severe hypoxia

Autor: Zhiling Xu, Ruli Afandi, Yonggang Lv, Xiaoying Hao, Li Yang, Yongqiang Sha

Publikováno v: Life sciences. 189

Aims Severe hypoxia always inhibits the cell proliferation, osteogenic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs), and hinders bone defect repair. Herein we explored the effects of mechano-growth factor (MGF) E peptide on t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e24ed1baf02d18bd715f46f2c6c0984
https://pubmed.ncbi.nlm.nih.gov/28927682

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MGF E peptide pretreatment improves collagen synthesis and cell proliferation of injured human ACL fibroblasts via MEK-ERK1/2 signaling pathway

Autor: Ruli Afandi, Li Yang, Yongqiang Sha, Bingbing Zhang, Yonggang Lv

Injured anterior cruciate ligament (ACL) is hard to heal due to the poor proliferative potential of ACL fibroblasts. To verify whether mechano-growth factor (MGF) E peptide can restore the cell proliferation of injured ACL fibroblasts, ACL fibroblast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d0968cdd43f998f711e34adb411a03

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