Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rukmani Pennathur-Das"'
Autor:
William C. Mentzer, Rukmani Pennathur-Das, Bertram H. Lubin, Kimberlie L. Cerrone, George L. Kenyon, Sydell Lewis, Rita A. Halpin
Publikováno v:
Journal of Protein Chemistry. 1:141-155
Imidoesters have been used in biological studies to measure interresidue distances of proteins and macromolecular complexes, and in hematology as antisickling agents. Treatment of human red blood cells with14C-labeled dimethyl adipimidate (DMA), a bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e231f36ec54d8de8c3d499535c1b7e
https://doi.org/10.1007/bf01025636
https://doi.org/10.1007/bf01025636
Autor:
Rukmani Pennathur-Das, Lee Levitt
Publikováno v:
Blood. 69:899-907
Tissue and marrow (BM) in vivo O2 tensions have been estimated at 23 to 40 mm Hg (3% to 5% O2). We have investigated cellular regulation of burst-forming units-erythroid (BFU-E) under 5% O2. BFU-E from BM mononuclear cells (MNC) were cultured in meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45640edc28be3ae6d6e7d38fa92a0adf
https://doi.org/10.1182/blood.v69.3.899.899
https://doi.org/10.1182/blood.v69.3.899.899
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure. 580:356-365
The effect of dimethyl adipimidate, a bifunctional imidoester, on the oxygen affinity of hemoglobin A has been studied. Treatment of human oxyhemoglobin with 5 mM dimethyl adipimidate at pH 8.5, room temperature is accompanied by an increase in oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb7bd9b16a2d2bc463d067c4d13527d1
https://doi.org/10.1016/0005-2795(79)90147-8
https://doi.org/10.1016/0005-2795(79)90147-8
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 706:80-85
Treatment of purified hemoglobin S with dimethyladipimidate (DMA), which results in inter- as well as intra-tetrameric cross-linking, induces an increase in oxygen affinity, a decrease in 2,3-diphosphoglyceric acid (DPG) effect and an increase in sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::616bc6835fee234b04c69d961e93d808
https://doi.org/10.1016/0167-4838(82)90376-4
https://doi.org/10.1016/0167-4838(82)90376-4
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 791:259-264
Dimethyl adipimidate (DMA), an effective antisickling agent in vitro, reacts with free amino groups producing chemically modified and cross-linked molecules. In this report, we have investigated the effect of cross-linked hemoglobin tetramers on sick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc84417eec9f8ea0b5bda72202c99280
https://doi.org/10.1016/0167-4838(84)90017-7
https://doi.org/10.1016/0167-4838(84)90017-7
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 704:389-397
Both chemically modified and cross-linked derivatives were formed when dimethyl adipimidate, an antisickling agent, reacted with hemoglobin S. About 1.3 mol dimethyl adipimidate (DMA) were incorporated into each mol of globin subunit. β s subunits w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b10faacbbe46ffc74cb7c08aeb4f5a
https://doi.org/10.1016/0167-4838(82)90059-0
https://doi.org/10.1016/0167-4838(82)90059-0
Autor:
Stanley M. Higashino, Bruce G. Nickerson, Michelle Minor, Elliott Vichinsky, Bertram H. Lubin, Klara Kleman, Rukmani Pennathur-Das
Publikováno v:
The Journal of pediatrics. 105(1)
An increase in hemoglobin concentration characterizes the normal compensatory response to chronic tissue hypoxia. We observed no such increase in 42 chronically hypoxic patients with cystic fibrosis, in whom the mean concentration was 12.6 gm/dl; one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08c926e918872acf7d55f970811c6ae
https://pubmed.ncbi.nlm.nih.gov/6737132
https://pubmed.ncbi.nlm.nih.gov/6737132
Publikováno v:
Hemoglobin and Oxygen Binding ISBN: 9781349064908
Hemoglobin and Oxygen Binding
Hemoglobin and Oxygen Binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62e2b1f62aaae8268502968d43552d43
https://doi.org/10.1007/978-1-349-06488-5_55
https://doi.org/10.1007/978-1-349-06488-5_55
