Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Rujuan, Bao"'
Autor:
Baiwen Chen, Jiajia Hu, Xianting Hu, Huifang Chen, Rujuan Bao, Yatao Zhou, Youqiong Ye, Meixiao Zhan, Wei Cai, Huabin Li, Hua-Bing Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Several mechanisms have been associated with transcriptional and post-transcriptional regulation of PD-L1 in cancer. Here the authors show that a RNA binding protein, DENR, positively regulates the translation of JAK2 and induces PD-L1 expression in
Externí odkaz:
https://doaj.org/article/09398a960963475ca57d3b0ed094f10f
Autor:
Jingjing Qi, Hongxiang Sun, Yao Zhang, Zhengting Wang, Zhenzhen Xun, Ziyi Li, Xinyu Ding, Rujuan Bao, Liwen Hong, Wenqing Jia, Fei Fang, Hongzhi Liu, Lei Chen, Jie Zhong, Duowu Zou, Lianxin Liu, Leng Han, Florent Ginhoux, Yingbin Liu, Youqiong Ye, Bing Su
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Tumour microenvironment profiling during colorectal cancer progression may enable the discovery of therapeutic targets. Here, single cell and spatial RNA sequencing of tumour and adjacent normal tissues reveals an interaction between FAP + fibroblast
Externí odkaz:
https://doaj.org/article/d01eebe932ec4da8b4999091fe015904
Autor:
Huifang Chen, Jiameng Yao, Rujuan Bao, Yu Dong, Ting Zhang, Yanhua Du, Gaoyang Wang, Duan Ni, Zhenzhen Xun, Xiaoyin Niu, Youqiong Ye, Hua-Bing Li
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Abstract Background The four major RNA adenosine modifications, i.e., m6A, m1A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regula
Externí odkaz:
https://doaj.org/article/b3d0ca45a3fa4330843d44dc2dd36ef2
Autor:
Youqiong Ye, Yongchang Zhang, Nong Yang, Qian Gao, Xinyu Ding, Xinwei Kuang, Rujuan Bao, Zhao Zhang, Chaoyang Sun, Bingying Zhou, Li Wang, Qingsong Hu, Chunru Lin, Jianjun Gao, Yanyan Lou, Steven H. Lin, Lixia Diao, Hong Liu, Xiang Chen, Gordon B. Mills, Leng Han
Publikováno v:
The Innovation, Vol 3, Iss 1, Pp 100194- (2022)
Immune checkpoint blockade (ICB) therapies exhibit substantial clinical benefit in different cancers, but relatively low response rates in the majority of patients highlight the need to understand mutual relationships among immune features. Here, we
Externí odkaz:
https://doaj.org/article/09672521fa364d2190843121c17ef63d
Autor:
Yao Liu, Zhenzhen Xun, Kun Ma, Shuhang Liang, Xianying Li, Shuo Zhou, Linmao Sun, Yufeng Liu, Yanhua Du, Xinyu Guo, Tianming Cui, Huanran Zhou, Jizhou Wang, Dalong Yin, Ruipeng Song, Shugeng Zhang, Wei Cai, Fanzheng Meng, Hongrui Guo, Bo Zhang, Di Yang, Rujuan Bao, Qingsong Hu, Jiabei Wang, Youqiong Ye, Lianxin Liu
Publikováno v:
Journal of Hepatology. 78:770-782
Autor:
Yu Dong, Hua-Bing Li, Duan Ni, Rujuan Bao, Yanhua Du, Xiaoyin Niu, Zhenzhen Xun, Huifang Chen, Youqiong Ye, Jiameng Yao, Gaoyang Wang, Ting Zhang
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer
Molecular Cancer
BackgroundThe four major RNA adenosine modifications, i.e., m6A, m1A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regulation in im
Autor:
Jingjing, Qi, Hongxiang, Sun, Yao, Zhang, Zhengting, Wang, Zhenzhen, Xun, Ziyi, Li, Xinyu, Ding, Rujuan, Bao, Liwen, Hong, Wenqing, Jia, Fei, Fang, Hongzhi, Liu, Lei, Chen, Jie, Zhong, Duowu, Zou, Lianxin, Liu, Leng, Han, Florent, Ginhoux, Yingbin, Liu, Youqiong, Ye, Bing, Su
Publikováno v:
Nature communications. 13(1)
Colorectal cancer (CRC) is among the most common malignancies with limited treatments other than surgery. The tumor microenvironment (TME) profiling enables the discovery of potential therapeutic targets. Here, we profile 54,103 cells from tumor and
Autor:
Huifang Chen, Jiameng Yao, Rujuan Bao, Dong, Yu, Zhang, Ting, Yanhua Du, Gaoyang Wang, Ni, Duan, Zhenzhen Xun, Xiaoyin Niu, Youqiong Ye, Li, Hua-Bing
Additional file 1 : Figure S1. Overview of study design. (A) Flowchart of the steps in the performed analyses. Figure S2. Analysis of mutation frequency and CNV in TCGA- COAD/READ. (A) The mutation frequency of RNA modification “writers” among 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e0618179426cc3c64df11a68675e45
Publikováno v:
Blood and Genomics. 2:137-140
Autor:
Shemin Lu, Michael Roth, Xudong Yang, Xiaojun Yang, Rujuan Bao, Qingzhu Sun, Xuemei Tang, Li Liu, Ai Jin
Publikováno v:
Journal of cellular physiology. 234(11)
The deregulated cross-talk between airway epithelial cells with subepithelial fibroblasts during inflammation drives the pathogenesis of asthma. Bioinformatics analysis and luciferase activity assay suggested that B cell lymphoma-2 (BCL2) and CXC lig