Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ruizhu Zeng"'
Autor:
Ruizhu Zeng, Harwin Sidik, Kim S. Robinson, Franklin L. Zhong, Bruno Reversade, Mahmoud A. Pouladi
Publikováno v:
Stem Cell Research, Vol 40, Iss , Pp - (2019)
Rett syndrome (RTT) is a childhood neurodevelopmental disorder caused by mutations in MECP2. To study the molecular mechanisms underlying RTT, four sublines of H1 hESCs were generated, carrying a hemizygous knockout or mutant allele of MECP2. Exons 3
Externí odkaz:
https://doaj.org/article/b4e964aa11f34855b2d9d264bddf4dbf
Autor:
Poh Hui Chia, Franklin Lei Zhong, Shinsuke Niwa, Carine Bonnard, Kagistia Hana Utami, Ruizhu Zeng, Hane Lee, Ascia Eskin, Stanley F Nelson, William H Xie, Samah Al-Tawalbeh, Mohammad El-Khateeb, Mohammad Shboul, Mahmoud A Pouladi, Mohammed Al-Raqad, Bruno Reversade
Publikováno v:
eLife, Vol 7 (2018)
Calcium/calmodulin-dependent protein kinase II (CAMK2) plays fundamental roles in synaptic plasticity that underlies learning and memory. Here, we describe a new recessive neurodevelopmental syndrome with global developmental delay, seizures and inte
Externí odkaz:
https://doaj.org/article/db6a2998912a4cdc9e37796ad1f08f29
Autor:
Yunhai Luo, Suzanne A Hartford, Ruizhu Zeng, Teresa L Southard, Naoko Shima, John C Schimenti
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004471 (2014)
Genome maintenance in germ cells is critical for fertility and the stable propagation of species. While mechanisms of meiotic DNA repair and chromosome behavior are well-characterized, the same is not true for primordial germ cells (PGCs), which aris
Externí odkaz:
https://doaj.org/article/9f08f75606b542ceae80a4632429fbd8
Autor:
Mahmoud A. Pouladi, Kim S. Robinson, Harwin Sidik, Ruizhu Zeng, Franklin L. Zhong, Bruno Reversade
Publikováno v:
Stem cell research, 40:101533. Elsevier
Stem Cell Research, Vol 40, Iss, Pp-(2019)
Stem Cell Research
Stem Cell Research, Vol 40, Iss, Pp-(2019)
Stem Cell Research
Rett syndrome (RTT) is a childhood neurodevelopmental disorder caused by mutations in MECP2. To study the molecular mechanisms underlying RTT, four sublines of H1 hESCs were generated, carrying a hemizygous knockout or mutant allele of MECP2. Exons 3
Publikováno v:
Mucosal immunology
The vitamin A metabolite retinoic acid (RA) regulates adaptive immunity in the intestines, with well-characterized effects on IgA responses, Treg induction, and gut trafficking of T- and B-effector cells. It also controls the generation of convention
Autor:
Bruno Reversade, Hane Lee, Ascia Eskin, Mohammad Shboul, Mahmoud A. Pouladi, Samah Al-Tawalbeh, Franklin L. Zhong, Mohammad El-khateeb, Shinsuke Niwa, Carine Bonnard, Poh Hui Chia, Stanley F. Nelson, William H Xie, Kagistia Hana Utami, Mohammed Al-Raqad, Ruizhu Zeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1a5265d6b9e6bcea9d27347327e4634
https://doi.org/10.7554/elife.32451.018
https://doi.org/10.7554/elife.32451.018
Autor:
Enrico Petretto, Radoslaw M. Sobota, Bernice Sim, Yihui Huang, Kagistia Hana Utami, Donovan Low, Sarah R. Langley, Yi Lin Tay, Nathan Harmston, Florent Ginhoux, Ruizhu Zeng, Folefac Aminkeng, Amin Ziaei, Mahmoud A. Pouladi, Xiaohong Xu, Jolene Ooi
Publikováno v:
Cell Reports. 26:2494-2508.e7
In Huntington disease (HD), the analysis of tissue-specific CAG repeat length effects has been challenging, given the difficulty in obtaining relevant patient tissues with a broad range of CAG repeat lengths. We used genome editing to generate an all
Autor:
K. Mark Ansel, Betty Diamond, Katharina Lahl, Mike Lee, Dirk Baumjohann, Sun Jung Kim, Husein Hadeiba, Eugene C. Butcher, John Morton, Ruizhu Zeng, Payal Watchmaker, Alexander L. Dent
Publikováno v:
Nature immunology, vol 15, iss 1
Dendritic cells (DCs) that orchestrate mucosal immunity have been studied in mice. Here we characterized human gut DC populations and defined their relationship to previously studied human and mouse DCs. CD103(+)Sirpα(-) DCs were related to human bl
Autor:
Josephine Lum, Masayuki Otsuka, Marta Garcia-Miralles, Jinmiao Chen, Tamer T. Onder, Yoshihisa Kitamura, Esther Wing Hei Mok, Chi Ching Goh, Sandra Hubert, Florent Ginhoux, Benoit Malleret, Sonia Garel, Ahmet Gül, Shohei Kawanishi, Ruizhu Zeng, Steffen Jung, Kazuyuki Takata, Tara Huber, Nurhidaya Binte Shadan, Evan W. Newell, Tatsuya Kozaki, Anis Larbi, Ivy Low, Dong Shin Park, Jinqiu Zhang, Donovan Low, Tay Seok Wei, Christopher Z. W. Lee, Laurent Rénia, Lai Guan Ng, Eishi Ashihara, Morgane Sonia Thion, Peter See, Gillian Low, Kerem Fidan, Mahmoud A. Pouladi, Kagistia Hana Utami, Michael Poidinger, Shawn Lim, Yochai Wolf, Bernett Lee, Svetoslav Chakarov
Publikováno v:
Immunity
Immunity, Elsevier, 2017, 47 (1), pp.183-198.e6. ⟨10.1016/j.immuni.2017.06.017⟩
Immunity, Elsevier, 2017, 47 (1), pp.183-198.e6. ⟨10.1016/j.immuni.2017.06.017⟩
Summary Tissue macrophages arise during embryogenesis from yolk-sac (YS) progenitors that give rise to primitive YS macrophages. Until recently, it has been impossible to isolate or derive sufficient numbers of YS-derived macrophages for further stud
Autor:
Robert Yuan, Cecilia Oderup, Eugene C. Butcher, Mike Lee, Aida Habtezion, Husein Hadeiba, Ruizhu Zeng
Publikováno v:
Mucosal immunology
The vitamin A metabolite retinoic acid (RA) regulates intestinal immune responses through immunomodulatory actions on intestinal dendritic cells (DCs) and lymphocytes. Here, we show that retinoic acid also controls the generation of gut-tropic migrat