Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ruizhen Sun"'
Autor:
Ruizhen Sun, Ximei Zhang, Tiantian Gong, Yue Zhang, Qi Wang, Chenyao He, Jielan Ju, Chunmiao Jin, Wenxin Ding, Jingnan Gao, Jingling Shen, Qiuming Li, Zhiyan Shan
Publikováno v:
Biomolecules, Vol 14, Iss 5, p 509 (2024)
H19 is an essential imprinted gene that is expressed to govern normal embryonic development. During reprogramming, the parental pronuclei have asymmetric reprogramming capacities and the critical reprogramming factors predominantly reside in the male
Externí odkaz:
https://doaj.org/article/32f70406554e4e7eada53cab1d217bf5
Autor:
Binghua Xue, Yan Li, Yilong He, Renyue Wei, Ruizhen Sun, Zhi Yin, Gerelchimeg Bou, Zhonghua Liu
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151737 (2016)
Although the pig is considered an important model of human disease and an ideal animal for the preclinical testing of cell transplantation, the utility of this model has been hampered by a lack of genuine porcine embryonic stem cells. Here, we derive
Externí odkaz:
https://doaj.org/article/2dce311800c5427d9a3d184a76f6fe4b
Publikováno v:
Reproduction. 164:221-230
In brief Several factors affect the reprogramming efficiency of nuclear transfer embryos. This study shows that inhibiting 18S rRNA m6A methyltransferase METTL5 during nuclear transfer can improve the developmental rate of nuclear transfer embryos. A
Autor:
Ruizhen Sun, Tiantian Gong, Hui Liu, Jingling Shen, Bin Wu, Qi Jiang, Qi Wang, Yue Zhang, Lian Duan, Jing Hu, Qiuming Li, Lei Lei, Zhiyan Shan
Publikováno v:
Journal of Molecular Histology. 53:623-634
Differentiated cells can be reprogrammed to embryonic stem cell-like cells called induced pluripotent stem cells (iPSCs), in which the natural developmental differentiation process is reversed. It is unclear whether the multi-lineage cells can be iso
Autor:
Huamin Yin, Zhendong Wang, Jiaxin Liu, Ying Li, Li Liu, Peijun Huang, Wenhang Wang, Zhiyan Shan, Ruizhen Sun, Jingling Shen, Lian Duan
Publikováno v:
Life Sciences. 324:121734
Autor:
Gerelchimeg Bou, Jia Guo, Shichao Liu, Shimeng Guo, Gantulga Davaakhuu, Qi Lv, Binghua Xue, Shupei Qiao, Jiawei Lv, Xiaogang Weng, Jianchao Zhao, Yuting Zhang, Yilong He, Heng Zhang, Zhuang Chai, Yan Liu, Yanbo Yu, Bo Qu, Ruizhen Sun, Xinghui Shen, Lei Lei, Zhonghua Liu
Publikováno v:
Cell reports. 41(8)
Oct4 is exclusively expressed in rodent inner cell mass (ICM) but silenced in its trophectoderm (TE). However, for many non-rodent animals, including pig, cattle, rabbit, goat, and human, OCT4 has a remarkable expression in early TE. This study, appl
Autor:
Jingling Shen, Zhiyan Shan, Feng Liu, Lei Lei, Ruizhen Sun, Xing-Hui Shen, Xinglin Hu, Hui Liu, Zhaojun Liu, Meng Gao
Publikováno v:
Cellular Reprogramming. 22:90-98
Induced pluripotent stem cell (iPSC) technology refers to the reprogramming of terminally differentiated somatic cells into pluripotent stem cells by introducing specific transcription factors that are known to regulate pluripotency, including Oct4,
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2018 (2018)
BioMed Research International, Vol 2018 (2018)
Foam cell formation and macrophage polarization are involved in the pathologic development of atherosclerosis, one of the most important human diseases affecting large and medium artery walls. This study was designed to assess the effects of rapamyci
Autor:
Hui, Liu, Zhaojun, Liu, Meng, Gao, Xinglin, Hu, Ruizhen, Sun, Xinghui, Shen, Feng, Liu, Jingling, Shen, Zhiyan, Shan, Lei, Lei
Publikováno v:
Cellular reprogramming. 22(2)
Induced pluripotent stem cell (iPSC) technology refers to the reprogramming of terminally differentiated somatic cells into pluripotent stem cells by introducing specific transcription factors that are known to regulate pluripotency, including Oct4,
Autor:
Yukuan Feng, Ruizhen Sun, Jing Hu, Qiaoshi Zhao, Yanshuang Wu, Zhiyan Shan, Lei Lei, Yanli Gu, Lian Duan, Na Li
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Patient-specific induced pluripotent stem cells (iPSCs) have the potential to be useful in the treatment of human diseases. While prior studies have reported multiple methods to generate iPSCs, DNA methylation continues to limit the totipotency and r