6α-Acetoxy-7α-Hydroxy-Vouacapan Isolated from Pterodon pubescens Benth. Fruit’s with Selective Activity against Prostate Cancer Cell Line: Artifact or Natural Product?

Autor: Carvalho Je, Lloret Fc, Foglio Ma, Sousa Imo, Santos Ccj, Ruiz Altg, Medina Ls, Queiroz Nca

Publikováno v: Medicinal & Aromatic Plants.

Challenges encountered in standardization of plant-derived drugs involves the determination of many parameters that implies quality control methods throughout the entire process from growing conditions to the final product. This study highlights the

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https://doi.org/10.4172/2167-0412.1000238

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Antibacterial profile and antiproliferative activities over human tumor cells of new silver(I) complexes containing two distinct trifluoromethyl uracil isomers.

Autor: de Menezes Pereira G; Institute of Chemistry, University of Campinas - UNICAMP, PO Box 6154, 13083-970 Campinas, SP, Brazil., Bormio Nunes JH; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria., Macedo VS; Chemistry Collegiate, Federal University of Tocantins - UFT, PO Box 66, 77402-970 Gurupi, TO, Brazil., Pereira DH; Chemistry Collegiate, Federal University of Tocantins - UFT, PO Box 66, 77402-970 Gurupi, TO, Brazil; Department of Chemistry, Technological Institute of Aeronautics (ITA), 12228-900 São José dos Campos, SP, Brazil., Buglio KE; Faculty of Pharmaceutical Sciences, University of Campinas - UNICAMP, 13083-871 Campinas, SP, Brazil., Affonso DD; Faculty of Pharmaceutical Sciences, University of Campinas - UNICAMP, 13083-871 Campinas, SP, Brazil., Ruiz ALTG; Faculty of Pharmaceutical Sciences, University of Campinas - UNICAMP, 13083-871 Campinas, SP, Brazil., de Carvalho JE; Faculty of Pharmaceutical Sciences, University of Campinas - UNICAMP, 13083-871 Campinas, SP, Brazil., Frajácomo SCL; Department of Biological and Health Sciences, University of Araraquara - UNIARA, 14801-320 Araraquara, SP, Brazil., Lustri WR; Department of Biological and Health Sciences, University of Araraquara - UNIARA, 14801-320 Araraquara, SP, Brazil., Lima CSP; Department of Anesthesiology, Oncology and Radiology, Faculty of Medical Sciences, University of Campinas - UNICAMP, Campinas 13083-887, SP, Brazil., Bergamini FRG; Laboratory of Synthesis of Bioinspired Molecules, Institute of Chemistry, Federal University of Uberlândia - UFU, 38400-902 Uberlândia, MG, Brazil. Electronic address: bergamini@ufu.br., Cuin A; Institute of Exact Sciences, Department of Chemistry, Federal University of Juiz de Fora - UFJF, 36036-330 Juiz de Fora, MG, Brazil., Masciocchi N; Department of Science and High Technology, University of Insubria, 21100 Varese, VA, Italy., Corbi PP; Institute of Chemistry, University of Campinas - UNICAMP, PO Box 6154, 13083-970 Campinas, SP, Brazil. Electronic address: ppcorbi@unicamp.br.

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2024 Oct 01; Vol. 262, pp. 112752. Date of Electronic Publication: 2024 Oct 01.

Novel Bidentate Amine Ligand and the Interplay between Pd(II) and Pt(II) Coordination and Biological Activity.

Autor: Oliveira LS; Institute of Chemistry, University of Campinas, Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo, Brazil., Rosa LB; Institute of Biology, University of Campinas, Cidade Universitária Zeferino Vaz -, Barão Geraldo, Campinas, São Paulo, Brazil., Affonso DD; Faculty of Pharmaceutical Sciences, University of Campinas, Cidade Universitária Zeferino Vaz -, Barão Geraldo, Campinas, São Paulo, Brazil., Santos IA; Institute of Biomedical Sciences, Federal University of Uberlândia, João Naves de Ávila Avenue, 2121 -, Santa Mônica, Uberlândia, Minas Gerais, Brazil.; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Woodhouse, Leeds, LS2 9JT, UK., Da Silva JC; Institute of Chemistry, University of Campinas, Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo, Brazil., Rodrigues GC; Institute of Chemistry, University of Campinas, Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo, Brazil., Harris M; School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Woodhouse, Leeds, LS2 9JT, UK., Jardim ACG; Institute of Biomedical Sciences, Federal University of Uberlândia, João Naves de Ávila Avenue, 2121 -, Santa Mônica, Uberlândia, Minas Gerais, Brazil.; Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University, Cristóvão Colombo street, 2265 -, Jardim Nazareth. São José do Rio Preto, São Paulo, Brazil., Nakahata DH; Institute of Chemistry, Federal University of Goiás, Esperança Avenue, Campus Samambaia., Goiânia, Goiás, Brazil., Sabino JR; Institute of Physics, Federal University of Goiás, Esperança Avenue, Campus Samambaia., Goiânia, Goiás, Brazil., de Carvalho JE; Faculty of Pharmaceutical Sciences, University of Campinas, Cidade Universitária Zeferino Vaz -, Barão Geraldo, Campinas, São Paulo, Brazil., Miguel DC; Institute of Biology, University of Campinas, Cidade Universitária Zeferino Vaz -, Barão Geraldo, Campinas, São Paulo, Brazil., Ruiz ALTG; Faculty of Pharmaceutical Sciences, University of Campinas, Cidade Universitária Zeferino Vaz -, Barão Geraldo, Campinas, São Paulo, Brazil., Abbehausen C; Institute of Chemistry, University of Campinas, Cidade Universitária Zeferino Vaz - Barão Geraldo, Campinas, São Paulo, Brazil.

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2024 Mar 15; Vol. 25 (6), pp. e202300696. Date of Electronic Publication: 2024 Feb 12.

Mass spectrometry as a tool for the dereplication of specialised metabolites from Pterocaulon angustifolium DC.

Autor: Moreno BP; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil., Pereira FA; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil., Andrade AAR; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil., Cabral MRP; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil., Battistella AC; Assuntos regulatórios, Universidade Tecnológica Federal do Paraná, R. Cristo Rei, Toledo, PR, Brazil., Tiuman TS; Assuntos regulatórios, Universidade Tecnológica Federal do Paraná, R. Cristo Rei, Toledo, PR, Brazil., Foglio MA; Faculdade de Ciências Farmacêuticas, UNICAMP, Rua Cândido Portinari, Campinas, SP, Brazil., Ruiz ALTG; Faculdade de Ciências Farmacêuticas, UNICAMP, Rua Cândido Portinari, Campinas, SP, Brazil., do Carmo MRB; Departamento de Biologia Geral, Universidade Estadual de Ponta Grossa, UEPG, Ponta Grossa, PR, Brazil., Sarragiotto MH; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil., Baldoqui DC; Departamento de Química, Universidade Estadual de Maringá, UEM, Maringá, PR, Brazil.

Publikováno v: Natural product research [Nat Prod Res] 2023 Dec 03, pp. 1-8. Date of Electronic Publication: 2023 Dec 03.