SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

Autor: Chae, Heeyoung, Augustin, Robert, Gatineau, Eva, Mayoux, Eric, Bensellam, Mohammed, Antoine, Nancy, Khattab, Firas, Lai, Bao-Khanh, Brusa, Davide, Stierstorfer, Birgit, Klein, Holger, Singh, Bilal, Ruiz, Lucie, Pieper, Michael, Mark, Michael, Herrera, Pedro L., Gribble, Fiona M., Reimann, Frank, Wojtusciszyn, Anne, Broca, Christophe, Rita, Nano, Piemonti, Lorenzo, Gilon, Patrick

Publikováno v: In Molecular Metabolism December 2020 42

SGLT2 is not expressed in pancreatic alpha and beta cells and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

Autor: Gilon, Patrick, Chae, Heeyoung, Antoine, Nancy, Lai, Bao Khanh, Singh, Bilal, Ruiz, Lucie, Wojtusciszyn, Anne, Broca, Christophe, Stierstorfer, Birgit, Klein, Thomas, Mayoux, Eric, Pieper, Michael, Mark, Michael, Augustin, Robert, 55th EASD Annual Meeting of the European Association for the Study of Diabetes

Publikováno v: Diabetologia, Vol. 62, no.Suppl 1, p. S125 (2019)

BACKGROUND AND AIMS: SGLT2 inhibitors (SGLT2i), such as dapagliflozin and empagliflozin, are effective glucose-lowering medications with a unique, insulin-independent mechanism that is to promote glycosuria. SGTL2i-induced glycosuria is associated wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1493::ee6272345ac28fdcebc33297b0e7488e
https://hdl.handle.net/2078.1/230684

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Die romanischen Orts- und Flurnamen von Sargans

Autor: Bolliger Ruiz, Lucie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::15f71eaae2d80f60cb449463ac4ea74d

SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans

Autor: Nancy Antoine, Lucie Ruiz, Holger Klein, Patrick Gilon, Anne Wojtusciszyn, Fiona M. Gribble, Frank Reimann, Robert Augustin, Bao-Khanh Lai, Bilal Singh, Michael P. Pieper, Eva Gatineau, Nano Rita, Mohammed Bensellam, Pedro Luis Herrera, Birgit Stierstorfer, Firas Khattab, Heeyoung Chae, Lorenzo Piemonti, Davide Brusa, Michael Mark, Eric Mayoux, Christophe Broca

Publikováno v: Molecular Metabolism
Molecular metabolism, vol. 42, pp. 101071
Molecular metabolism
Molecular metabolism, Elsevier, 2020, 42, pp.101071. ⟨10.1016/j.molmet.2020.101071⟩
Molecular Metabolism (2020) P. 101071
Molecular Metabolism, Vol 42, Iss, Pp 101071-(2020)

Objective Sodium-glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i), or gliflozins, are anti-diabetic drugs that lower glycemia by promoting glucosuria, but they also stimulate endogenous glucose and ketone body production. The likely causes of thes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13201cec4df0020051e57406d53b494a
https://pubmed.ncbi.nlm.nih.gov/32896668