Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Ruiyun Guo"'
Autor:
Boxin Liu, Yan Wei, Jingjing He, Baofeng Feng, Yimeng Chen, Ruiyun Guo, Matthew D. Griffin, Seán O. Hynes, Sanbing Shen, Yan Liu, Huixian Cui, Jun Ma, Timothy O’Brien
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Diabetic cardiomyopathy (DCM) is a serious health-threatening complication of diabetes mellitus characterized by myocardial fibrosis and abnormal cardiac function. Human umbilical cord mesenchymal stromal cells (hUC-MSCs) are a po
Externí odkaz:
https://doaj.org/article/64b15c2321bc4d389fa891334d6b314f
Autor:
Xiaofeng Du, Desheng Kong, Ruiyun Guo, Boxin Liu, Jingjing He, Jinyu Zhang, Asiamah Ernest Amponsah, Huixian Cui, Jun Ma
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Spinal cord injury (SCI) is a serious clinical condition that has pathological changes such as increased neuroinflammation and nerve tissue damage, which eventually manifests as fibrosis of the injured segment and the development
Externí odkaz:
https://doaj.org/article/23c539e0f7c44ba3b6148dc8367bc5f8
Autor:
Jingjing He, Boxin Liu, Xiaofeng Du, Yan Wei, Desheng Kong, Baofeng Feng, Ruiyun Guo, Ernest Amponsah Asiamah, Matthew D. Griffin, Sean O. Hynes, Sanbing Shen, Yan Liu, Huixian Cui, Jun Ma, Timothy O’Brien
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background and aims Mesenchymal stromal cells (MSCs) a potentially effective disease-modulating therapy for diabetic nephropathy (DN) but their clinical translation has been hampered by incomplete understanding of the optimal timing of admin
Externí odkaz:
https://doaj.org/article/5d0a65d625d44f7abac7708253ffd38f
Autor:
Lianying Wang, Ruiyun Guo, Xiaohan Zhang, Zijing Zhou, Herman Yao Akogo, Zewei Fu, Yongzhou Song, Ming Li, Jun Ma
Publikováno v:
Stem Cell Research, Vol 80, Iss , Pp 103506- (2024)
The APOE 4 allele remains the primary genetic risk factor for sporadic Alzheimer’s disease, whereas the APOE 2 allele emerges as a protective factor. Therapeutic approaches in murine models with human APOE alleles, such as modulating APOE levels an
Externí odkaz:
https://doaj.org/article/c760ed744a384e399caa9628cc395dfa
Autor:
Yunfei Zhang, Yali Liu, Wei Yan, Xuecong Zhang, Yu Hou, Zijing Zhou, Ruiyun Guo, Guobin Liu, Jun Ma
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103201- (2023)
In this study, fibroblasts were harvested and isolated from a healthy 14-year-old male donor and reprogrammed with four Yamanaka factors containing Oct3/4, Sox2, Klf4 and c-Myc to generate human induced pluripotent stem cell (iPSC) lines. The resulti
Externí odkaz:
https://doaj.org/article/2d6a03d43aaa402da7e7bae65c30c517
Autor:
Mingjing Zhang, Mei Yu, Ruiyun Guo, Yunfei Zhang, Xiaohan Zhang, Jingyi Sun, Jing Zhang, Xia Wang, Jun Ma
Publikováno v:
Stem Cell Research, Vol 69, Iss , Pp 103116- (2023)
The ε4 allele of the lipoprotein E gene (APOE4) is the strongest genetic risk factor associated with sporadic Alzheimer's disease (sAD). While the neuronal cell type-specific function of APOE4 in connection with AD pathology remains understudied. Th
Externí odkaz:
https://doaj.org/article/96345dc54d904fd1bd026a3aa4e519d1
Autor:
Shuxing Cao, Ruiyun Guo, Zewei Fu, Yukun Liu, Taotao Wu, Zijing Zhou, Jinyu Zhang, Xin Liu, Yongzhou Song, Jun Ma
Publikováno v:
Stem Cell Research, Vol 68, Iss , Pp 103052- (2023)
Sporadic Alzheimer’s disease (sAD) is the most common neurodegenerative disease worldwide, which is characterized by the progressive cognitive dysfunction and behavioral impairment. Here, we generated a human induced pluripotent stem cell (iPSC) li
Externí odkaz:
https://doaj.org/article/c21e30679ac64d7089ba419c394fe29c
Autor:
Yangzi Zheng, Ruiyun Guo, Xiang Li, Tianou He, Weicong Wang, Qi Zhan, Rui Li, Ke Zhang, Shangdong Ji, Mingshang Jin
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Metal phosphides with multi-element components and amorphous structure represent a novel kind of electrocatalysts for promising activity and durability towards the oxygen evolution reaction (OER). In this work, a two-step strategy, including alloying
Externí odkaz:
https://doaj.org/article/0130092c2f35490aa441d4651f640255
Publikováno v:
Stem Cell Research, Vol 63, Iss , Pp 102840- (2022)
Apolipoprotein E (APOE) gene encodes three protein isoforms (APOEε-22/ε-33/ε-44), which governs the transportation and metabolism of lipoproteins differently. While abnormalities in lipid and lipoprotein metabolism have been identified as risk fac
Externí odkaz:
https://doaj.org/article/022c641361c2450088b5aa2bc16bbc76
Autor:
Ruiyun Guo, Xin Liu, Jinyu Zhang, Xiaowei Ma, Dongyun Gou, Zhenhuan Ma, Lei Wang, Jun Ma, Huixian Cui
Publikováno v:
Stem Cell Research, Vol 61, Iss , Pp 102746- (2022)
The ε4 allele of the Apolipoprotein E gene (APOE4) continues to be the strongest genetic risk factor associated with sporadic Alzheimer’s disease since its discovery compared to the most common ε3 allele. Nevertheless, there is a lack of APOE4-mu
Externí odkaz:
https://doaj.org/article/abeed0e3787c4fe3a08c2c23a6737955