Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Ruiwu, Liu"'
Autor:
Michelle Hu, Ruiwu Liu, Noemi Castro, Liliana Loza Sanchez, Lapamas Rueankham, Julie A. Learn, Ruiqi Huang, Kit S. Lam, Kermit L. Carraway
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Derivatives of the potassium-sparing diuretic amiloride are preferentially cytotoxic toward tumor cells relative to normal cells, and have the capacity to target tumor cell populations resistant to currently employed therapeutic agents. Howe
Externí odkaz:
https://doaj.org/article/e2c9d3c858cc4cc5b0a5666d7202c03c
Autor:
Dake Hao, Jonathan Lin, Ruiwu Liu, Christopher Pivetti, Kaeli Yamashiro, Linda M. Schutzman, Junichiro Sageshima, Mimmie Kwong, Nataliya Bahatyrevich, Diana L. Farmer, Misty D. Humphries, Kit S. Lam, Alyssa Panitch, Aijun Wang
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 467-479 (2023)
Implantable vascular devices are widely used in clinical treatments for various vascular diseases. However, current approved clinical implantable vascular devices generally have high failure rates primarily due to their surface lacking inherent funct
Externí odkaz:
https://doaj.org/article/a998f809726e4772bf64c10097549356
Autor:
Dake Hao, Ruiwu Liu, Tomas Gonzalez Fernandez, Christopher Pivetti, Jordan Elizabeth Jackson, Edwin Samuel Kulubya, Hong-Jiang Jiang, Hai-Yang Ju, Wen-Liang Liu, Alyssa Panitch, Kit S. Lam, J. Kent Leach, Diana L. Farmer, Aijun Wang
Publikováno v:
Bioactive Materials, Vol 20, Iss , Pp 179-193 (2023)
Significant progress has been made in designing bone materials capable of directing endogenous cells to promote vascularized bone regeneration. However, current strategies lack regulation of the specific endogenous cell populations for vascularized b
Externí odkaz:
https://doaj.org/article/2129904cf30f4f3ab1e3a50d6ff8890d
Autor:
Hengyue Song, Kewa Gao, Dake Hao, Andrew Li, Ruiwu Liu, Bryan Anggito, Boyan Yin, Qianyu Jin, Vanessa Dartora, Kit S. Lam, Lucas R. Smith, Alyssa Panitch, Jianda Zhou, Diana L. Farmer, Aijun Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The lack of vascularization associated with deep burns delays the construction of wound beds, increases the risks of infection, and leads to the formation of hypertrophic scars or disfigurement. To address this challenge, we have fabricated a multi-f
Externí odkaz:
https://doaj.org/article/6044fdbd2b2949d9945fc9e6112cbd08
Autor:
Siqi He, Tanaya Walimbe, Hongyuan Chen, Kewa Gao, Priyadarsini Kumar, Yifan Wei, Dake Hao, Ruiwu Liu, Diana L. Farmer, Kit S. Lam, Jianda Zhou, Alyssa Panitch, Aijun Wang
Publikováno v:
Bioactive Materials, Vol 10, Iss , Pp 460-473 (2022)
Diabetic ischemic wound treatment remains a critical clinical challenge. Neovascularization plays a significant role in wound healing during all stages of the tissue repair process. Strategies that enhance angiogenesis and neovascularization and impr
Externí odkaz:
https://doaj.org/article/e0cf9bdd9cf540b48f856c8d765dacfb
Autor:
Pei-Pei Yang, Yi-Jing Li, Yan Cao, Lu Zhang, Jia-Qi Wang, Ziwei Lai, Kuo Zhang, Diedra Shorty, Wenwu Xiao, Hui Cao, Lei Wang, Hao Wang, Ruiwu Liu, Kit S. Lam
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Self-assembling peptides have a range of potential applications but developing self-assembling sequences can be challenging. Here, the authors report on a one-bead one-compound combinatorial library where fluorescence is used to detect the potential
Externí odkaz:
https://doaj.org/article/b500e47a873f4ec0ad4a0291c2826f1c
Autor:
Silvia Hilt, Ruiwu Liu, Izumi Maezawa, Tatu Rojalin, Hnin H. Aung, Madhu Budamagunta, Ryan Slez, Qizhi Gong, Randy P. Carney, John C. Voss
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Several neurodegenerative diseases are driven by misfolded proteins that assemble into soluble aggregates. These “toxic oligomers” have been associated with a plethora of cellular dysfunction and dysregulation, however the structural features und
Externí odkaz:
https://doaj.org/article/575a1b403849475ca12a31cf7a3d0cda
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Currently, there are no effective medications to reverse periodontal disease (PD)-induced bone loss. The objective of this study was to test a new anabolic compound, LLP2A-Ale, or with the combination treatment of mesenchymal stro
Externí odkaz:
https://doaj.org/article/1b11b61104734105a516216caa95e93b
Autor:
Min Jiang, Ruiwu Liu, Lixian Liu, Alexander Kot, Xueping Liu, Wenwu Xiao, Junjing Jia, Yuanpei Li, Kit S. Lam, Wei Yao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Activation of osteogenic cells is essential for bone regeneration. Here, the authors screen a peptide library and identify 2 compounds that promote osteogenic progenitor cell differentiation in vitro, and show that they increase bone formation and fr
Externí odkaz:
https://doaj.org/article/5ff53e7e00854267b6246944d4363749
Autor:
Wenwu Xiao, Weijie Ma, Sixi Wei, Qianping Li, Ruiwu Liu, Randy P. Carney, Kevin Yang, Joyce Lee, Alan Nyugen, Ken Y. Yoneda, Kit S. Lam, Tianhong Li
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-18 (2019)
Abstract Background α3β1 integrin is a promising cancer biomarker and drug target. We previously identified a 9-amino-acid cyclic peptide LXY30 for detecting α3β1 integrin on the surface of live tumor cells. This study was undertaken to character
Externí odkaz:
https://doaj.org/article/d3b7ff4eee8d4b6a8dc82bb79073bae6