Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ruiping Gu"'
Autor:
Yue Guo, Dekang Gan, Fangyuan Hu, Yun Cheng, Jian Yu, Boya Lei, Qinmeng Shu, Ruiping Gu, Gezhi Xu
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-12 (2022)
Abstract Background Retinal neurodegeneration is induced by a variety of environmental insults and stresses, but the exact mechanisms are unclear. In the present study, we explored the involvement of cytosolic mitochondrial DNA (mtDNA), resulting in
Externí odkaz:
https://doaj.org/article/e44ef145be974a59bd6df18c4649527c
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background Pathological stimuli cause mitochondrial damage and leakage of mitochondrial DNA (mtDNA) into the cytosol, as demonstrated in many cell types. The cytosolic mtDNA then drives the activation of noninfectious inflammation. Retinal m
Externí odkaz:
https://doaj.org/article/6808013915094a48b3c566161805b662
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background We present a case of intrusion of a suture knot 15 years after scleral buckling surgery. Case presentation A 62-year-old woman with high myopia had undergone scleral buckling surgery in her left eye 15 years previously for rhegmat
Externí odkaz:
https://doaj.org/article/6d2ffe055a7d4bc1be9535df21cc243d
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Background: Aberrant neovascularization resulting from inappropriate angiogenic signaling is closely related to many diseases, such as cancer, cardiovascular disease, and proliferative retinopathy. Although some factors involved in regulating pathoge
Externí odkaz:
https://doaj.org/article/3089284b93384566931ded56eac0edde
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-12 (2018)
Abstract Background Attention is increasingly being given to microglia-related inflammation in neovascular diseases, such as diabetic retinopathy and age-related macular disease. Evidence shows that activated microglia contribute to disruption of the
Externí odkaz:
https://doaj.org/article/24fbf1a6fc9846d99289614353e46529
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-6 (2018)
Abstract Background Numerous studies have suggested that the integrity of the cone interdigitation zone (IZ) could be considered to be a marker of photoreceptor damage and its recovery. However, little is known about the IZ in healthy eyes. Our prese
Externí odkaz:
https://doaj.org/article/c603ce1e8c5e4855b481c35c98e4a9be
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 375-388 (2018)
Background/Aims: Lipocalin 2 (LCN2), an important mediator of a variety of cellular processes, is involved in regulating the inflammatory response, but its roles in different inflammatory diseases are controversial. Because the role of LCN2 in ocular
Externí odkaz:
https://doaj.org/article/164ad4fabccb48eb9c0d87df8d6c3aad
Publikováno v:
BMC Ophthalmology, Vol 18, Iss 1, Pp 1-5 (2018)
Abstract Background Epiretinal membranes (ERMs), secondary to retinal cell proliferation on the retinal surface, usually affect patients over 50 years of age but occur rarely in children. Here we report the case of a 4-year-old patient with a unilate
Externí odkaz:
https://doaj.org/article/89f9977ab7e54efca27046bf9e1ae222
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Purpose: The anti-inflammatory activities of protein glucocorticoid-induced leucine zipper (GILZ) have been demonstrated in vivo and in vitro. Here, we examined the potential effect of a synthetic peptide derived from the leucine zipper motif and pro
Externí odkaz:
https://doaj.org/article/6f845b84e63442f5b99e6ab2095bf232
Publikováno v:
Journal of Ophthalmology, Vol 2015 (2015)
Purpose. To characterize the optical coherence tomography (OCT) findings in late-stage Vogt-Koyanagi-Harada (VKH) disease and its correlation with visual function. Methods. The records of patients with late-stage VKH disease (defined as ≥12 months
Externí odkaz:
https://doaj.org/article/0abff32cf9c94652a7e4d2587ef74a17