Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ruiping Dong"'
Autor:
Min Huang, Chengping Ma, Yan Li, Ruiping Dong, Rongrong Pang, Shuizhen Huang, Qiang Fu, Libo Zhang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract The accuracy of blood group identification is the basis of blood transfusion safety. In order to increase the detection rate of weak agglutination, unexpected antibodies (UAb) and blood subtypes for pre-transfusion testing, the blood group s
Externí odkaz:
https://doaj.org/article/8dbde5bb56a941aa95a6f89805c85b8d
Autor:
Ting Xu, Qiong Hua, Haolan Lu, Wael A. Harb, John Gong, Cody J. Peer, Yue He, Siying Xu, David T.L. Liu, Ruiping Dong, Kyriakos P. Papadopoulos, Ni Lu
Publikováno v:
Oncologist
Lessons Learned Subcutaneous injection was an effective route of administration for envafolimab with a favorable pharmacokinetic profile in patients with previously treated advanced solid tumors. Subcutaneous envafolimab was well tolerated and had du
Autor:
Yi Chen, Ruiping Dong, Min Huang, Yi Su, Jian Ding, Shuai Tang, Meiyu Geng, Li Lei, Leping Li
Publikováno v:
Cancer Research. 80:3760-3760
The mitogen-activated protein kinases (MAPK) pathway, often known as the RAS-RAF-MEK-ERK signal cascade, is the most frequently mutated signal pathway in cancer, which makes the components of this pathway attractive targets for anticancer drug develo
Autor:
Shilin Xue, Wenlian Xu, Ni Lu, Ruiping Dong, Danming Zhu, Toshio Shimizu, Meng Fu, Pilin Wang, Takako Eguchi Nakajima, Xiaoxiao Wang, Ting Xu, Haolan Lu, John Gong, Walt Cao, David T.L. Liu
Publikováno v:
Journal of Clinical Oncology. 37:2609-2609
2609 Background: KN035 is a novel fusion protein of humanized anti-PD-L1 single domain antibody and human IgG1 Fc, formulated for subcutaneous (SC) injection. A phase I safety and pharmacokinetic (PK) study was conducted in Japanese patients. Methods
Autor:
Ruiping Dong, Yun Zhang, Huilong Liu, John Gong, David T.L. Liu, Rongrui Liu, Walt Cao, Shukui Qin, Chuanhua Zhao, Yaoyue Zhang, Meng Fu, Gairong Zhang, Jianming Xu, Pilin Wang, Ni Lu, Xiaoxiao Wang, Haolan Lu, Wenlian Xu, Ru Jia, Ting Xu
Publikováno v:
Journal of Clinical Oncology. 37:2608-2608
2608 Background: KN035 is a novel fusion protein of humanized anti-PD-L1 single domain antibody and human IgG1 Fc fragment, formulated for subcutaneous (SC) injection. Methods: The escalation phase followed a modified 3+3 design with a 28-day DLT eva
Autor:
Xiaoxiao Wang, Ni Lu, Gairong Zhang, Pilin Wang, Lin Yihui, Wenlian Xu, Yaoyue Zhang, Xiaoyu Ma, Chuanhua Zhao, Rongrui Liu, Ruiping Dong, Yun Zhang, Shukui Qin, Jianming Xu, Ting Xu, Liwei Yuan, Ru Jia, John Gong, Yan Wang, Yue He
Publikováno v:
Journal of Clinical Oncology. 36:e15138-e15138
e15138Background: KN035 is a novel programmed death-ligand 1(PD-L1) antagonist and formulated to high protein concentration (200 mg/ml) and provided as a transparent liquid solution for subcutaneou...
Autor:
Xiaodan Feng, Ming Li, Wen Sun, Ruiping Dong, Jing Wang, Jiaqi Tang, Xiuzhen Pan, Gong Cheng, Hongfeng Ji, Dan Hu, Junchao Ge, Youjun Feng, Feng Zheng, Changjun Wang, Bo Wu, Fuquan Hu, Xina Hao, Zhimin Yin, Peiju Shi
Publikováno v:
Journal of Bacteriology. 191:2601-2612
Streptococcus suis serotype 2 is an emerging zoonotic pathogen responsible for a wide range of life-threatening diseases in pigs and humans. However, the pathogenesis of S. suis serotype 2 infection is not well understood. In this study, we report th
Autor:
Arata Goto, RuiPing Dong
Publikováno v:
Haigan. 46:267-275
CetuximabはマウスとヒトIgG1のキメラ型モノクローナル抗体であり,ヒト上皮増殖因子受容体(EGFR)を標的としている.CetuximabはヒトEGFRの細胞外領域に結合し,リガンド結合を競合的に阻
Autor:
Gong Cheng, Youjun Feng, Jing Wang, Xiaodan Feng, Jiaqi Tang, Ruiping Dong, Ming Li, Changjun Wang, Yaqing Dong, Fuquan Hu, Di Liu, Dan Hu, Junchao Ge, Xiuzhen Pan, Feng Zheng, Min Cao
Publikováno v:
Archives of microbiology. 191(1)
Sortase A (SrtA), originally identified as a transpeptidase in Staphylococcus aureus, plays key roles in full virulence of pathogenic bacteria. In silico genome-wide search suggested a srtA homologue from 05ZYH33, a Chinese human isolate of streptoco
Autor:
RuiPing Dong
Publikováno v:
Nature Reviews Drug Discovery. 11:100-100