Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ruinan Shen"'
Autor:
Suzhen Lin, Yimei Shu, Ruinan Shen, Yifan Zhou, Hong Pan, Lu He, Fang Fang, Xue Zhu, Xinrui Wang, Ying Wang, Wei Xu, Jianqing Ding
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-22 (2024)
Abstract Background Overactivated microglia are a key contributor to Parkinson’s disease (PD) by inducing neuroinflammation. CD200R1, a membrane glycoprotein mainly found on microglia, is crucial for maintaining quiescence with its dysregulation li
Externí odkaz:
https://doaj.org/article/51844cb3be804e7fb9710883a1f1fc5c
Autor:
Puyu Li, Xinyi Zhou, Ningdi Luo, Ruinan Shen, Xue Zhu, Min Zhong, Sijia Huang, Naying He, Haiying Lyu, Yufei Huang, Qianyi Yin, Liche Zhou, Yong Lu, Yuyan Tan, Jun Liu
Publikováno v:
NeuroImage, Vol 297, Iss , Pp 120701- (2024)
Due to a high degree of symptom overlap in the early stages, with movement disorders predominating, Parkinson's disease (PD) and multiple system atrophy (MSA) may exhibit a similar decline in motor areas, yet they differ in their spread throughout th
Externí odkaz:
https://doaj.org/article/20073750185e429cb6cd547b6d3e336d
Autor:
Suzhen Lin, André D.G. Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni, Alfredo Castro, Kijung Sung, Ruinan Shen, Jazmin B. Florio, Michael L. Mante, Jianqing Ding, Brian Spencer, Eliezer Masliah, Robert A. Rissman, Chengbiao Wu
Publikováno v:
Neurobiology of Disease, Vol 178, Iss , Pp 106010- (2023)
Mutations or triplication of the alpha synuclein (ASYN) gene contribute to synucleinopathies including Parkinson's disease (PD), Dementia with Lewy bodies (DLB) and multiple system atrophy (MSA). Recent evidence suggests that ASYN also plays an impor
Externí odkaz:
https://doaj.org/article/ce172def23994913ad183ff932d3046b
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 26, Iss , Pp 100535- (2022)
SARS-CoV-2 vaccine has considered being the most effective method to prevent SARS-CoV-2 infection. The safety and effectiveness of the SARS-CoV-2 vaccine has been confirmed. However, in very rare cases, autoimmune neurological diseases may occur. In
Externí odkaz:
https://doaj.org/article/ff13a26c724f4088a0ef7fc1950cfa7b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Ras and Rab interactor 3 (RIN3) functions as a Guanine nucleotide Exchange Factor (GEF) for some members of the Rab family of small GTPase. By promoting the activation of Rab5, RIN3 plays an important role in regulating endocytosis and endocytic traf
Externí odkaz:
https://doaj.org/article/d7c23f1c8c844ef1b7bfef3ac8ca59dc
Autor:
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-19 (2020)
Abstract Background In Alzheimer’s Disease (AD), about one-third of the risk genes identified by GWAS encode proteins that function predominantly in the endocytic pathways. Among them, the Ras and Rab Interactor 3(RIN3) is a guanine nucleotide exch
Externí odkaz:
https://doaj.org/article/fba437dace9840c482d15ffe0b14536d
Corrigendum: Association of Two Polymorphisms in CCL2 With Parkinson's Disease: A Case-Control Study
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/983bf004194f477cbaf1b000eaa081c6
Autor:
Lu He, Suzhen Lin, Hong Pan, Ruinan Shen, Mengyan Wang, Zhihao Liu, Shiyao Sun, Yuyan Tan, Ying Wang, Shengdi Chen, Jianqing Ding
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Low DJ-1 protein level caused by DJ-1 gene mutation leads to autosomal recessive Parkinson’s disease (PD) due to impaired antioxidative activity. In sporadic PD patients, although mutations were rarely found, lower DJ-1 protein level was also repor
Externí odkaz:
https://doaj.org/article/014adf3f79ba46d89a9346ad2b1ca07f
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Background: Parkinson's disease (PD) is the most common neurodegenerative movement disorder that is known to be related to neuro-inflammation. Chemokines participate in this process usually through upregulation of expression levels, which are closely
Externí odkaz:
https://doaj.org/article/6d028a9f88844f6f8c0014564f723fa6
Publikováno v:
Mitochondrial DNA. Part B. Resources, Vol 4, Iss 2, Pp 2114-2115 (2019)
The complete chloroplast (cp) genome sequence of Actinidia eriantha was sequenced and assembled using Illumina paired-end data. The cp genome from A. eriantha is 156,964 bp in length, composed of a pair of 23,892 bp inverted repeat regions (IR) separ
Externí odkaz:
https://doaj.org/article/eb461d70a4724a7bb4e28287239776f4