Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ruimao Zheng"'
Autor:
Zihan Yu, Xianju Li, Yanni Quan, Jiawen Chen, Jiarui Liu, Nairen Zheng, Shuwen Liu, Yini Wang, Wanlin Liu, Chen Qiu, Yi Wang, Ruimao Zheng, Jun Qin
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114142- (2024)
Summary: Despite medical advances, there remains an unmet need for better treatment of obesity. Itaconate, a product of the decarboxylation of the tricarboxylic acid cycle intermediate cis-aconitate, plays a regulatory role in both metabolism and imm
Externí odkaz:
https://doaj.org/article/10d0695edfb7427db75c5b62238f62db
Autor:
Wen Z. Yang, Hengchang Xie, Xiaosa Du, Qian Zhou, Yan Xiao, Zhengdong Zhao, Xiaoning Jia, Jianhui Xu, Wen Zhang, Shuang Cai, Zhangjie Li, Xin Fu, Rong Hua, Junhao Cai, Shuang Chang, Jing Sun, Hongbin Sun, Qingqing Xu, Xinyan Ni, Hongqing Tu, Ruimao Zheng, Xiaohong Xu, Hong Wang, Yu Fu, Liming Wang, Xi Li, Haitao Yang, Qiyuan Yao, Tian Yu, Qiwei Shen, Wei L. Shen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Thermal homeostasis is vital for mammals and is controlled by brain neurocircuits. Yet, the neural pathways responsible for cold defense regulation are still unclear. Here, we found that a pathway from the lateral parabrachial nucleus (LPB)
Externí odkaz:
https://doaj.org/article/f5bdff405dbb4eb691d7608784cd2695
Autor:
Shizhang Wei, Tingting He, Xu Zhao, Manyi Jing, Haotian Li, Lisheng Chen, Ruimao Zheng, Yanling Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Farnesoid X receptor (FXR) is a key metabolic target of bile acids (BAs) and is also a target for drugs against several liver diseases. However, the contribution of FXR in the pathogenesis of cholestasis is still not fully understood. The
Externí odkaz:
https://doaj.org/article/9244b1fb76004527a36cfc57b5e363aa
Publikováno v:
Biology, Vol 12, Iss 6, p 833 (2023)
Inter-tissue communication (ITC) is critical for maintaining the physiological functions of multiple tissues and is closely related to the onset and development of various complex diseases. Nevertheless, there is no well-organized data resource for k
Externí odkaz:
https://doaj.org/article/97930bb918024859bf255f1f48176be0
Autor:
Jingliang Zhang, Chenyu Zhang, Xiaoling Chen, Bingwei Wang, Weining Ma, Yang Yang, Ruimao Zheng, Zhuo Huang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Jingliang Zhang et al. examine how dysfunctional PKA signaling impacts neuronal activity and seizure susceptibility in a mouse model of temporal lobe epilepsy. Their data suggest that autophosphorylation of the RIIβ subunit regulates neuronal excita
Externí odkaz:
https://doaj.org/article/9c4c3b9f0dd34dfd9978b39e043e5a31
Autor:
Chenyu Zhang, Miao Zhao, Bingwei Wang, Zhijie Su, Bingbing Guo, Lihua Qin, Weiguang Zhang, Ruimao Zheng
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102134- (2021)
Parkinson's disease (PD) is a chronic neurodegenerative disorder that is characterized by motor symptoms as a result of a loss of dopaminergic neurons in the substantia nigra pars compacta (SNc), accompanied by chronic neuroinflammation, oxidative st
Externí odkaz:
https://doaj.org/article/41ff2f86a943499182c058561039cc03
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Cerebral small vessel disease (cSVD) and neurodegeneration are the two main causes of dementia and are considered distinct pathological processes, while studies have shown overlaps and interactions between the two pathological pathways. M
Externí odkaz:
https://doaj.org/article/837d79c860fe4baab89543f1f380e376
Obesity-Associated Anxiety Is Prevalent among College Students and Alleviated by Calorie Restriction
Autor:
Junbo Wang, Xinyi Ran, Jinchen Ye, Run Deng, Weimin Dang, Yangyi Fan, Zhiping Hu, Lei Yang, Wentian Dong, Yifei Lv, Kunzhan Lin, Maoran Li, Yuhe Jiang, Ruimao Zheng
Publikováno v:
Nutrients, Vol 14, Iss 17, p 3518 (2022)
Anxiety is a common disorder among college students, especially those with obesity. Obesity contributes to metabolic disorders and disturbs the neural functions, further leading to anxiety. In this cross-sectional study, we aimed to determine the ass
Externí odkaz:
https://doaj.org/article/c989cfb2943440fdbd734cf81241b0c9
Publikováno v:
Nutrients, Vol 13, Iss 10, p 3487 (2021)
Dietary barley (Hordeum vulgare L.) leaf (BL) is a popular functional food known to have potential health benefits; however, the effect of BL in colorectal cancer prevention has not been examined. Here, we examined the role of BL on the prevention of
Externí odkaz:
https://doaj.org/article/9fa40af7c519467483e7df89beeeb99f
Publikováno v:
Biology; Volume 12; Issue 6; Pages: 833
Inter-tissue communication (ITC) is critical for maintaining the physiological functions of multiple tissues and is closely related to the onset and development of various complex diseases. Nevertheless, there is no well-organized data resource for k