Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Ruikai, Du"'
Autor:
Beilei Dong, Rui Xue, Jianwei Li, Shukuan Ling, Wenjuan Xing, Zizhong Liu, Xinxin Yuan, Junjie Pan, Ruikai Du, Xinming Shen, Jingwen Zhang, Youzhi Zhang, Yingxian Li, Guohui Zhong
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-16 (2024)
Abstract Sleep deprivation (SD) has emerged as a critical concern impacting human health, leading to significant damage to the cardiovascular system. However, the underlying mechanisms are still unclear, and the development of targeted drugs is laggi
Externí odkaz:
https://doaj.org/article/85a04c16ef07485290baa498768b9b60
Autor:
Ruikai Du, Yunbo Lv, Haifeng Wu, Baoli Zhang, Yuanxi Liu, Shichao Xu, Shan Li, Zhen‐Gang Wang
Publikováno v:
Smart Molecules, Vol 2, Iss 3, Pp n/a-n/a (2024)
Abstract Enzymes with active sites involving histidine selectively utilize either the δ‐ or ε‐nitrogen atom (Nδ or Nε) of the histidine imidazole for catalysis. However, evaluating the impact of Nδ and Nε is difficult, and directly integrat
Externí odkaz:
https://doaj.org/article/3df13136d9e94169af163b9693f4d21b
Autor:
Yuheng Li, Weijia Sun, Jianwei Li, Ruikai Du, Wenjuan Xing, Xinxin Yuan, Guohui Zhong, Dingsheng Zhao, Zizhong Liu, Xiaoyan Jin, Junjie Pan, Youyou Li, Qi Li, Guanghan Kan, Xuan Han, Shukuan Ling, Xiqing Sun, Yingxian Li
Publikováno v:
Bone Research, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Bone marrow mesenchymal stem cell (BMSC) osteogenic differentiation and osteoblast function play critical roles in bone formation, which is a highly regulated process. Long noncoding RNAs (lncRNAs) perform diverse functions in a variety of b
Externí odkaz:
https://doaj.org/article/0cccad74ce81418bb274377ead712451
Autor:
Weijia Sun, Yuheng Li, Jianwei Li, Yingjun Tan, Xinxin Yuan, Haoye Meng, Jianting Ye, Guohui Zhong, XiaoYan Jin, Zizhong Liu, Ruikai Du, Wenjuan Xing, Dingsheng Zhao, Jinping Song, Youyou Li, Junjie Pan, Yunzhang Zhao, Qi Li, Aiyuan Wang, Shukuan Ling, Rongji Dai, Yingxian Li
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Mechanical force loading is essential for maintaining bone homeostasis, and unloading exposure can lead to bone loss. Osteoclasts are the only bone resorbing cells and play a crucial role in bone remodeling. The molecular mechanisms underlyi
Externí odkaz:
https://doaj.org/article/b3b4a4799a66481cb95d9ea2f7d7a2a2
Autor:
Zizhong Liu, Gui Luo, Ruikai Du, Guanghan Kan, Xuan Han, Guohui Zhong, Wenjuan Xing, Ying Cui, Weijia Sun, Jianwei Li, Yuheng Li, Dingsheng Zhao, Xinxin Yuan, Xiaoyan Jin, Yanping Han, Huiyuan Sun, Shukuan Ling, Yingxian Li
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108556- (2023)
Summary: Spaceflight is physically demanding and can negatively affect astronauts’ health. It has been shown that the human gut microbiota and cardiac function are affected by spaceflight and simulated spaceflight. This study investigated the effec
Externí odkaz:
https://doaj.org/article/9ff8438dad7c43169ed721894d88904f
Autor:
Yixuan Li, Zizhong Liu, Gui Luo, Haiyun Lan, Pu Chen, Ruikai Du, Gongchao Jing, Lu Liu, Xiaohan Cui, Yongzhi Li, Yanping Han, Jian Xu, Hongwei Zhu, Shukuan Ling, Yingxian Li
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106615- (2023)
Summary: Spaceflight is rigorous and dangerous environment which can negatively affect astronauts’ health and the entire mission. The 60 days of 6° head-down bed rest (HDBR) experiment provided us with an opportunity to trace the change of gut mic
Externí odkaz:
https://doaj.org/article/517ac2753661488687d706ae75b38c7a
Autor:
Weijia Sun, Shuai Guo, Yuheng Li, JianWei Li, Caizhi Liu, Yafei Chen, Xuzhao Wang, Yingjun Tan, Hua Tian, Cheng Wang, Ruikai Du, Guohui Zhong, Sai Shi, Biao Ma, Chang Qu, Jingxuan Fu, Xiaoyan Jin, Dingsheng Zhao, Yong Zhan, Shukuan Ling, Hailong An, Yingxian Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Osteoclast over-activation leads to bone loss and chloride homeostasis is important for osteoclast function. Here, the authors show that Anoctamin 1 controls bone resorption by coupling Cl− channel activation with RANKL-RANK signaling transduction.
Externí odkaz:
https://doaj.org/article/ad9a828c99b74de39cdca2c41f2000f0
Autor:
Caizhi Liu, Xingcheng Gao, Yuheng Li, Weijia Sun, Youjia Xu, Yingjun Tan, Ruikai Du, Guohui Zhong, Dingsheng Zhao, Zizhong Liu, Xiaoyan Jin, Yinlong Zhao, Yinbo Wang, Xinxin Yuan, Junjie Pan, Guodong Yuan, Youyou Li, Wenjuan Xing, Guanghan Kan, Yanqing Wang, Qi Li, Xuan Han, Jianwei Li, Shukuan Ling, Yingxian Li
Publikováno v:
Bone Research, Vol 10, Iss 1, Pp 1-16 (2022)
Abstract Mechanical stimulation plays an important role in bone remodeling. Exercise-induced mechanical loading enhances bone strength, whereas mechanical unloading leads to bone loss. Increasing evidence has demonstrated that long noncoding RNAs (ln
Externí odkaz:
https://doaj.org/article/8f953ed5ef8f42e78e5a3972d8fb44db
Autor:
Jianqi Xue, Ruikai Du, Shukuan Ling, Jinping Song, Xinxin Yuan, Caizhi Liu, Weijia Sun, Yuheng Li, Guohui Zhong, Yinbo Wang, Guodong Yuan, Xiaoyan Jin, Zizhong Liu, Dingsheng Zhao, Youyou Li, Wenjuan Xing, Yuanyuan Fan, Zifan Liu, Junjie Pan, Zhen Zhen, Yunzhang Zhao, Qinna Yang, Jianwei Li, Yan-Zhong Chang, Yingxian Li
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
As hematopoietic stem cells can differentiate into all hematopoietic lineages, mitigating the damage to hematopoietic stem cells is important for recovery from overdose radiation injury. Cells in bone marrow microenvironment are essential for hematop
Externí odkaz:
https://doaj.org/article/56ac4792ff004ff0ba455882b8645d34
Autor:
Yinglong Zhao, Guohui Zhong, Ruikai Du, Dingsheng Zhao, Jianwei Li, Yuheng Li, Wenjuan Xing, Xiaoyan Jin, Wenjuan Zhang, Weijia Sun, Caizhi Liu, Zizhong Liu, Xinxin Yuan, Guanghan Kan, Xuan Han, Qi Li, Yan-Zhong Chang, Yingxian Li, Shukuan Ling
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Microgravity prominently affected cardiovascular health, which was the gravity-dependent physical factor. Deep space exploration had been increasing in frequency, but heart function was susceptible to conspicuous damage and cardiac mass declined in w
Externí odkaz:
https://doaj.org/article/8259364f6af24044be184f31aabed650