Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ruihua Ji"'
Autor:
Xiaogang Luo, Ruihua Ji, Qianru Liu, Xiaoxue Xiao, Wengang Song, Huazhang An, Yingke Li, Jun Zhou
Publikováno v:
Journal of Innate Immunity, Vol 15, Iss 1, Pp 380-396 (2023)
The cytosolic viral nucleic acid-sensing pathways converge on the protein kinase TANK-binding kinase 1 (TBK1) and the transcription factor interferon (IFN)-regulatory factor 3 (IRF3) to induce type I IFN production and antiviral immune responses. How
Externí odkaz:
https://doaj.org/article/86d3b96f5b6143d988d6a6dbe5f4a288
Autor:
Peng Gao, Xianwei Ma, Ming Yuan, Yulan Yi, Guoke Liu, Mingyue Wen, Wei Jiang, Ruihua Ji, Lingxi Zhu, Zhen Tang, Qingzhuo Yu, Jing Xu, Rui Yang, Sheng Xia, Mingjin Yang, Jianping Pan, Hongbin Yuan, Huazhang An
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Ubiquitination is a prevalent post translational modification. Here, the authors show a pivotal role for Nedd4l in the regulation of antiviral immunity via promotion of ubiquitination of TRAF3 and go on to show disruption of Nedd4l both in vitro and
Externí odkaz:
https://doaj.org/article/bffac75e109345e0b74fe29816ce9cfd
Publikováno v:
Apoptosis. 28:222-232
There are an increasing number of experiments to study programmed cell death/apoptosis, one of the characteristics of which is DNA fragmentation. The only current method for in situ detection of DNA fragmentation is Terminal deoxynucleotidyl transfer
Autor:
Sheng Xia, Hongbin Yuan, Mingjin Yang, Ruihua Ji, Xianwei Ma, Wei Jiang, Lingxi Zhu, Jianping Pan, Mingyue Wen, Guoke Liu, Rui Yang, Huazhang An, Jing Xu, Peng Gao, Yulan Yi, Zhen Tang, Ming Yuan, Qingzhuo Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Ubiquitination is one of the most prevalent protein posttranslational modifications. Here, we show that E3 ligase Nedd4l positively regulates antiviral immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3. Deficiency of Nedd4l significa
Autor:
Wenqi Zhao, Yu Zhang, Ruihua Ji, Gillian E. Knight, Geoffrey Burnstock, Hongbin Yuan, Zhenghua Xiang
Publikováno v:
Purinergic Signal
In this study, the distribution patterns of P2X1 to P2X7 receptors in the anterior pituitary cells of rat were studied with single-, double-, and triple-labeling immunofluorescence, combined method of immunofluorescence and in situ hybridization, and
Autor:
Zhiwu Tong, Xiahong Xie, Huiming Ge, Ruihua Jiao, Tingting Wang, Xincun Wang, Wenying Zhuang, Gang Hu, Renxiang Tan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 881-892 (2024)
Peptides are a particular molecule class with inherent attributes of some small-molecule drugs and macromolecular biologics, thereby inspiring continuous searches for peptides with therapeutic and/or agrochemical potentials. However, the success rate
Externí odkaz:
https://doaj.org/article/f57ed497beed48be9dba5149c0fbe7ed
Autor:
Rui Yang, Lingxi Zhu, Jing Xu, Peng Gao, Qingzhuo Yu, Hongbin Yuan, Ruihua Ji, Xianwei Ma, Huazhang An, Xiaogang Luo, Guixian Jiang, Jun Zhou, Qianru Liu
Publikováno v:
Molecular immunology. 122
Thousand and one amino acid kinase 1 (TAOK1) is a member of Ste20-like kinases, but its function in regulating inflammatory responses remains largely unknown. In this study, we identify TAOK1 as a positive regulator of TLR4-triggered inflammatory res
Publikováno v:
Internetware
The development of mobile apps has become the current mantra for any business' success. The rise of many types of mobile devices and mobile OS has instantly created the need to develop multiple versions for the same app. In order to grasp as much mar
Publikováno v:
Journal of International Medical Research, Vol 52 (2024)
Objective To investigate the effects of hydrogen therapy on epileptic seizures in rats with refractory status epilepticus and the underlying mechanisms. Methods Status epilepticus was induced using pilocarpine. The effects of hydrogen treatment on ep
Externí odkaz:
https://doaj.org/article/db360b96138245b8a39448b326e70b6b
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Determining bulk moduli is central to high-throughput screening of ultraincompressible materials. However, existing approaches are either too inaccurate or too expensive for general applications, or they are limited to narrow chemistries. He
Externí odkaz:
https://doaj.org/article/67df384be3cc40068d33570667cc3933