Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ruida Hou"'
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101036- (2024)
Externí odkaz:
https://doaj.org/article/48d522afcad0472b8ab63aebe5d0f8bf
Autor:
Lexiao Li, Yu Chen, Madison N. Sluter, Ruida Hou, Jiukuan Hao, Yin Wu, Guo-Yun Chen, Ying Yu, Jianxiong Jiang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Sialic acid immunoglobulin-like lectin E (Siglec-E) is a subtype of pattern recognition receptors found on the surface of myeloid cells and functions as a key immunosuppressive checkpoint molecule. The engagement between Siglec-E and the lig
Externí odkaz:
https://doaj.org/article/de65a61e55a24eaa91c84ffcee7b8c85
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113966- (2022)
Neuroblastoma (NB) is the most common pediatric extracranial solid tumor arising from neural crest cells of the developing sympathetic nervous system. Despite marked advances in cancer treatment, the survival rate of high-risk NB remains unsatisfacto
Externí odkaz:
https://doaj.org/article/1f01f1f6d9804e36a061061b1e3fc937
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
The urea transporter UT-B is widely expressed and has been studied in erythrocyte, kidney, brain and intestines. Interestingly, UT-B gene has been found more abundant in bladder than any other tissue. Recently, gene analyses demonstrate that SLC14A1
Externí odkaz:
https://doaj.org/article/847eaf17b0aa4cefb5fb61a33dad1899
Autor:
Marwa M. Nagib, Sicheng Zhang, Nelufar Yasmen, Lexiao Li, Ruida Hou, Ying Yu, Vijay K. Boda, Zhongzhi Wu, Wei Li, Jianxiong Jiang
Publikováno v:
Epilepsia
OBJECTIVE: As a key member of transient receptor potential (TRP) superfamily, TRP canonical 3 (TRPC3) regulates calcium homeostasis and contributes to neuronal excitability. Ablation of TRPC3 lessens pilocarpine-induced seizures in mice, suggesting t
Autor:
Madison N. Sluter, Jianxiong Jiang, Nelufar Yasmen, Lexiao Li, Ruida Hou, Ying Yu, Jiawang Liu
Publikováno v:
J Med Chem
In the wake of health disasters associated with the chronic use of cyclooxygenase-2 (COX-2) inhibitor drugs, it has been widely proposed that modulation of downstream prostanoid synthases or receptors might provide more specificity than simply shutti
Publikováno v:
Cancer Research. 83:4923-4923
Neuroblastoma (NB) is the most common pediatric extracranial solid tumor. Based on tumor stage and histological features, 50% of NBs are classified as high-risk diseases, a subtype characterized by a quite unsatisfactory long-term survival even with
Publikováno v:
ACS Pharmacology & Translational Science. 3:635-643
Prostaglandin E2 (PGE2) is elevated in the brain by excitotoxic insults and, in turn, aggravates the neurotoxicity mainly through acting on its Gαs-coupled receptor EP2, inspiring a therapeutic strategy of targeting this key proinflammatory pathway.
Autor:
Lexiao Li, Nelufar Yasmen, Ruida Hou, Seyoung Yang, Jae Yeol Lee, Jiukuan Hao, Ying Yu, Jianxiong Jiang
Publikováno v:
Neurotherapeutics
As the inducible terminal enzyme for prostaglandin E2 (PGE(2)) synthesis, microsomal PGE synthase-1 (mPGES-1) contributes to neuroinflammation and secondary brain injury after cerebral ischemia via producing excessive PGE(2). However, a proof of conc
Autor:
Ruida Hou, Ying Yu, Madison N. Sluter, Lexiao Li, Jiukuan Hao, Jie Fang, Jun Yang, Jianxiong Jiang
Publikováno v:
Cell Reports. 39:111000
Prostaglandin E