Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ruichen Jia"'
Autor:
Yanzhu Shen, Ruichen Jiang, Yanjun Huang, Yuming Wang, Sizheng Zhan, Xiangsheng Tang, Ping Yi
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-19 (2024)
Abstract Background Osteoarthritis (OA) is marked by the progressive degradation of joint cartilage and subchondral bone. The precise molecular mechanisms driving meniscus deterioration in OA, especially at the single-cell level, remain poorly unders
Externí odkaz:
https://doaj.org/article/efd4d084e2b745b689dfb0e1d101e632
Autor:
Biao Chen, Wenjie Ma, Xu Long, Hong Cheng, Huanhuan Sun, Jin Huang, Ruichen Jia, Xiaoxiao He, Kemin Wang
Publikováno v:
Analytical Chemistry. 94:2502-2509
DNA logic gates, as a class of smart molecular devices with excellent biocompatibility and convenient information processing mode, have been widely used for identification of cancer cells based on logic analysis of cancer biomarkers. However, most of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398eca9937b18c16f70f826211d7de9e
https://doi.org/10.1021/acs.analchem.1c04347
https://doi.org/10.1021/acs.analchem.1c04347
Autor:
Huanhuan Sun, Kemin Wang, Hong Cheng, Mingmin Huang, Xiaoxiao He, Ruichen Jia, Biao Chen, Jin Huang, Wenjie Ma
Publikováno v:
Analytical Chemistry. 93:14552-14559
Herein, we subtly engineered a pH and membrane receptor dual-activatable aptamer therapeutic for bispecific tumor cell imaging and in situ drug release by utilizing a hairpin-contained i-motif as the acid-responsive element to be complementary with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d76be00118dcebb1c0bb244a6c3aab
https://doi.org/10.1021/acs.analchem.1c03580
https://doi.org/10.1021/acs.analchem.1c03580
Autor:
Hong Cheng, Huizhen Wang, Kemin Wang, Huanhuan Sun, Ruichen Jia, Xiaoxiao He, Wenjie Ma, Jin Huang, Biao Chen
Publikováno v:
Analytical Chemistry. 93:10511-10518
In situ stimuli-responsive molecular devices have gained much attention in biomedical areas due to their characteristics of increased image contrast and drug accumulation. Herein, we present a hand-in-hand in situ tile assembly for improved visualiza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271d41fbd102e0e84d70cf98a9dd503e
https://doi.org/10.1021/acs.analchem.1c01453
https://doi.org/10.1021/acs.analchem.1c01453
Autor:
Biao Chen, Jin Huang, Xiaoxiao He, Hong Cheng, Kemin Wang, Huanhuan Sun, Ruichen Jia, Shuangdi Duan, Wenjie Ma
Publikováno v:
Chemical Science
Exploitation of stimuli-responsive nanoplatforms is of great value for precise and efficient cancer theranostics. Herein, an in situ activable “nanocluster-bomb” detonated by endogenous overexpressing legumain is fabricated for contrast-enhanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31859eec1b438ee1ec913853871359ee
https://doi.org/10.1039/d1sc03847h
https://doi.org/10.1039/d1sc03847h
Autor:
Ruichen Jia, Yitan Wang, Wenjie Ma, Jin Huang, Huanhuan Sun, Biao Chen, Hong Cheng, Xiaoxiao He, Kemin Wang
Publikováno v:
Analytical chemistry. 94(15)
The desire for a cancer theranostic system with simultaneously accurate diagnosis and efficient therapy is undeniably interminable. Heretofore, theranostic systems with simple components were designed for cancer theranostics but with confined accurac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff89272cd4cc35eaa85ce54ea7364922
https://pubmed.ncbi.nlm.nih.gov/35380798
https://pubmed.ncbi.nlm.nih.gov/35380798
Autor:
Xiaofeng Liu, Qing Wang, Yan Zheng, Shaoyuan Li, Yao Xu, Ruichen Jia, Yaqin Liu, Xiaohai Yang, Xiuhua Geng, Kemin Wang
Publikováno v:
Analytical Chemistry. 92:2853-2858
The exhaustive investigating interactions between recognition probes and amyloid aggregates, especially simultaneous recognition events, are challenging and crucial for the design of biosensing probes and further diagnosis of amyloid diseases. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79a10a97cd484620dafe15fcd27365f1
https://doi.org/10.1021/acs.analchem.9b05493
https://doi.org/10.1021/acs.analchem.9b05493
Autor:
Huizhen Wang, Dinggeng He, Kejing Wan, Kemin Wang, Yue Zhou, Jin Huang, Hong Cheng, Xiaoxiao He, Ruichen Jia
Publikováno v:
Chemical Communications. 56:12949-12952
A three-dimensional (3D) multipedal DNA walker triggered by the specific recognition between aptamers and proteins was developed for ultrasensitive tumor exosome sensing. A detection limit of 1 particle μL-1 was obtained with high selectivity. With
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d98710a17b29c411f6920b5d7771597
https://doi.org/10.1039/d0cc04360e
https://doi.org/10.1039/d0cc04360e
Autor:
Kemin Wang, Zenghui Li, Wenjie Ma, Biao Chen, Ruichen Jia, Yanli Lei, Hong Cheng, Shanzi Zou, Xiaoxiao He
Publikováno v:
The Analyst. 145:2562-2569
Aptamers are promising in cancer diagnosis and therapy, but their poor affinity under physiological conditions is a challenge. In view of the acidic microenvironment of solid tumors, we herein developed an extracellular pH-manipulated multivalent app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6c7971759aeab32054fc1a4867416d
https://doi.org/10.1039/d0an00101e
https://doi.org/10.1039/d0an00101e
Autor:
Hong Cheng, Ruichen Jia, Huanhuan Sun, Wenjie Ma, Kemin Wang, Xiaoxiao He, Yanli Lei, Jin Huang
Publikováno v:
Analytical Chemistry. 91:15107-15113
It has been reported that PIWI-interacting RNAs (piRNAs) play critical roles in activating invasion and metastasis, evading growth suppressors, and sustaining proliferative signaling of cancer and can be regarded as a novel biomarker candidate. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7577cbbb74bb5ec452985cfbda0a97c1
https://doi.org/10.1021/acs.analchem.9b03819
https://doi.org/10.1021/acs.analchem.9b03819