High-titre methylene blue-treated convalescent plasma as an early treatment for outpatients with COVID-19: a randomised, placebo-controlled trial.

Autor: Alemany A; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain. Electronic address: aalemany@flsida.org., Millat-Martinez P; ISGlobal, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain., Corbacho-Monné M; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain; Hospital Universitari Parc Taulí, I3PT, Sabadell, Spain., Malchair P; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Ouchi D; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain., Ruiz-Comellas A; Unitat de Suport a la Recerca de la Catalunya Central, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, Sant Fruitós de Bages, Spain; Health Promotion in Rural Areas Research Group, Gerència Territorial de la Catalunya Central, Institut Català de la Salut, Sant Fruitós de Bages, Spain; Universitat de Vic-Universitat Central de Catalunya, Vic, Spain., Ramírez-Morros A; Unitat de Suport a la Recerca de la Catalunya Central, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, Sant Fruitós de Bages, Spain., Rodríguez Codina J; Salut Catalunya Central, Hospital de Berga, Berga, Spain., Amado Simon R; Salut Catalunya Central, Hospital de Berga, Berga, Spain., Videla S; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Clinical Research Support Unit, HUB-IDIBELL, Bellvitge University Hospital and Bellvitge Biomedical Research Institute, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain; Pharmacology Unit, Department of Pathology and Experimental Therapeutics, School of Medicine and Health Sciences, IDIBELL, University of Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain., Costes G; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., Capdevila-Jáuregui M; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., Torrano-Soler P; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., San José A; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., Bonet Papell G; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain., Puig J; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., Otero A; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain; Clinical Research Support Unit, HUB-IDIBELL, Bellvitge University Hospital and Bellvitge Biomedical Research Institute, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain., Ruibal Suarez JC; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Zarauza Pellejero A; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Llopis Roca F; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Rodriguez Cortez O; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Garcia Garcia V; Emergency Department, Bellvitge University Hospital, Hospitalet de Llobregat, Spain., Vidal-Alaball J; Unitat de Suport a la Recerca de la Catalunya Central, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, Sant Fruitós de Bages, Spain; Health Promotion in Rural Areas Research Group, Gerència Territorial de la Catalunya Central, Institut Català de la Salut, Sant Fruitós de Bages, Spain; Universitat de Vic-Universitat Central de Catalunya, Vic, Spain., Millan A; Blood Bank Department, Banc de Sang i Teixits, Barcelona, Spain., Contreras E; Blood Bank Department, Banc de Sang i Teixits, Barcelona, Spain., Grifols JR; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Blood Bank Department, Banc de Sang i Teixits, Barcelona, Spain., Ancochea À; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Blood Bank Department, Banc de Sang i Teixits, Barcelona, Spain., Galvan-Femenia I; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Institute for Research in Biomedicine, The Barcelona Institute of Science and Technology, Barcelona, Spain., Piccolo Ferreira F; Bioclever, Barcelona, Spain., Bonet M; Bioclever, Barcelona, Spain., Cantoni J; Bioclever, Barcelona, Spain., Prat N; Gerència Territorial Metropolitana Nord, Institut Català de la Salut, Barcelona, Spain., Ara J; Universitat Autònoma de Barcelona, Barcelona, Spain; Gerència Territorial Metropolitana Nord, Institut Català de la Salut, Barcelona, Spain., Forcada Arcarons A; Gerència Territorial de la Catalunya Central, Institut Català de la Salut, Barcelona, Spain., Farré M; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain., Pradenas E; IrsiCaixa AIDS Research Institute, Germans Trias i Pujol Research Institute, Can Ruti Campus, Badalona, Spain., Blanco J; Universitat de Vic-Universitat Central de Catalunya, Vic, Spain; IrsiCaixa AIDS Research Institute, Germans Trias i Pujol Research Institute, Can Ruti Campus, Badalona, Spain., Àngel Rodriguez-Arias M; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain., Fernández Rivas G; Microbiology Department, Clinical Laboratory Metropolitana Nord, Badalona, Barcelona, Spain., Marks M; Hospital for Tropical Diseases, London, UK; Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK., Bassat Q; ISGlobal, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain; Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública, Madrid, Spain; ICREA, Pg Lluís Companys 23, Barcelona, Spain; Pediatrics Department, Hospital Sant Joan de Déu, Universitat de Barcelona, Esplugues, Barcelona, Spain; Centro de Investigação em Saúde de Manhiça, Maputo, Mozambique., Blanco I; Management Department, Clinical Laboratory Metropolitana Nord, Badalona, Barcelona, Spain., Baro B; ISGlobal, Hospital Clinic, Universitat de Barcelona, Barcelona, Spain., Clotet B; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Universitat Autònoma de Barcelona, Barcelona, Spain; Universitat de Vic-Universitat Central de Catalunya, Vic, Spain; IrsiCaixa AIDS Research Institute, Germans Trias i Pujol Research Institute, Can Ruti Campus, Badalona, Spain., Mitjà O; Fight AIDS and Infectious Diseases Foundation, Badalona, Spain; Infectious Diseases Department, Hospital Universitari Germans Trias i Pujol, Badalona, Spain; Universitat de Vic-Universitat Central de Catalunya, Vic, Spain; Lihir Medical Centre, International SOS, Lihir Island, Papua New Guinea.

Publikováno v: The Lancet. Respiratory medicine [Lancet Respir Med] 2022 Mar; Vol. 10 (3), pp. 278-288. Date of Electronic Publication: 2022 Feb 09.