Zobrazeno 1 - 10
of 517
pro vyhledávání: '"Rui-sheng Wang"'
Autor:
Matthew Moll, Julian Hecker, John Platig, Jingzhou Zhang, Auyon J. Ghosh, Katherine A. Pratte, Rui-Sheng Wang, Davin Hill, Iain R. Konigsberg, Joe W. Chiles, III, Craig P. Hersh, Peter J. Castaldi, Kimberly Glass, Jennifer G. Dy, Don D. Sin, Ruth Tal-Singer, Majd Mouded, Stephen I. Rennard, Gary P. Anderson, Gregory L. Kinney, Russell P. Bowler, Jeffrey L. Curtis, Merry-Lynn McDonald, Edwin K. Silverman, Brian D. Hobbs, Michael H. Cho
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105429- (2024)
Summary: Background: Genetic variants and gene expression predict risk of chronic obstructive pulmonary disease (COPD), but their effect on COPD heterogeneity is unclear. We aimed to define high-risk COPD subtypes using genetics (polygenic risk score
Externí odkaz:
https://doaj.org/article/a0549eb45ebc4c8e9d1d5f0c4da19d8b
Autor:
Xing Guo, Rui-Sheng Wang, Zhen-Ling Zhang, Hong-Wei Zhang, Sheng-Chao Wang, Shuai Zhang, Ya-Ning Wu, Ya-Jing Li, Jun Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionNon-small cell lung cancer (NSCLC) is a prominent lung cancer disease worldwide. Currently, commonly used methods, such as surgery and radiotherapy, have significant side effects. Traditional Chinese medicine (TCM) has become a research h
Externí odkaz:
https://doaj.org/article/0becca7ae8c84b72897f0ceb49c400bf
Autor:
Bradley A. Maron, Rui-Sheng Wang, Sergei Shevtsov, Stavros G. Drakos, Elena Arons, Omar Wever-Pinzon, Gordon S. Huggins, Andriy O. Samokhin, William M. Oldham, Yasmine Aguib, Magdi H. Yacoub, Ethan J. Rowin, Barry J. Maron, Martin S. Maron, Joseph Loscalzo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/50603cd66e7949c081913418f58fccd7
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 2, Pp 257-269 (2024)
Abstract High drug development costs and the limited number of new annual drug approvals increase the need for innovative approaches for drug effect prediction. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the cause of coronaviru
Externí odkaz:
https://doaj.org/article/5665341e05e443b1b2a22a646829cd71
Autor:
Shelsey W. Johnson, Rui-Sheng Wang, Michael R. Winter, Kari R. Gillmeyer, Katarina Zeder, Elizabeth S. Klings, Ronald H. Goldstein, Renda Soylemez Wiener, Bradley A. Maron
Publikováno v:
ERJ Open Research, Vol 10, Iss 3 (2024)
Background Clinical trials repurposing pulmonary arterial hypertension (PAH) therapies to patients with lung disease- or hypoxia-pulmonary hypertension (PH) (classified as World Health Organization Group 3 PH) have failed to show a consistent benefit
Externí odkaz:
https://doaj.org/article/19d8d7068a8744eb8e1d67da7977ec40
Autor:
Paola Paci, Giulia Fiscon, Federica Conte, Rui-Sheng Wang, Diane E. Handy, Lorenzo Farina, Joseph Loscalzo
Publikováno v:
npj Systems Biology and Applications, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract Despite advances in modern medicine that led to improvements in cardiovascular outcomes, cardiovascular disease (CVD) remains the leading cause of mortality and morbidity globally. Thus, there is an urgent need for new approaches to improve
Externí odkaz:
https://doaj.org/article/2607675e88ee47119101753e63d78227
Autor:
Bradley M. Wertheim, Rui-Sheng Wang, Christelle Guillermier, Christiane V.R. Hütter, William M. Oldham, Jörg Menche, Matthew L. Steinhauser, Bradley A. Maron
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
In pulmonary arterial hypertension (PAH), inflammation promotes a fibroproliferative pulmonary vasculopathy. Reductionist studies emphasizing single biochemical reactions suggest a shift toward glycolytic metabolism in PAH; however, key questions rem
Externí odkaz:
https://doaj.org/article/3241f24b97504570a5420e07c730d523
Autor:
Rui‐Sheng Wang, Joseph Loscalzo
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 1, Pp n/a-n/a (2023)
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which led to the current pandemic. Many factors, including age and comorbidities, influence the severi
Externí odkaz:
https://doaj.org/article/68816e10f15e4fe186b3f6bd26c9a513
Autor:
Rui‐Sheng Wang, Joseph Loscalzo
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 994-1005 (2021)
Abstract Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by pulmonary vascular remodeling leading to increased pulmonary vascular resistance and pulmonary arterial pressure. PAH is a highly morbid cardiopulmonary disease
Externí odkaz:
https://doaj.org/article/658a209cdbb0443eb34f39906b64e6de
Autor:
Bradley A. Maron, Rui-Sheng Wang, Sergei Shevtsov, Stavros G. Drakos, Elena Arons, Omar Wever-Pinzon, Gordon S. Huggins, Andriy O. Samokhin, William M. Oldham, Yasmine Aguib, Magdi H. Yacoub, Ethan J. Rowin, Barry J. Maron, Martin S. Maron, Joseph Loscalzo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Abstract Progress in precision medicine is limited by insufficient knowledge of transcriptomic or proteomic features in involved tissues that define pathobiological differences between patients. Here, myectomy tissue from patients with obstructive hy
Externí odkaz:
https://doaj.org/article/2926174a581e4c769ceef9c3aba4d547