Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Rui-ming Liu"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Activation of the NLRP3 inflammasome is a two-step process: the priming and the activating. The priming step involves the induction of NLRP3 and pro-IL-1β, while the activating step leads to the full inflammasome activation triggered by a N
Externí odkaz:
https://doaj.org/article/43e681b4f7614926973282c498f28878
Autor:
Tapasi Rana, Chunsun Jiang, Sami Banerjee, Nengjun Yi, Jaroslaw W. Zmijewski, Gang Liu, Rui-Ming Liu
Publikováno v:
Cells, Vol 12, Iss 15, p 2008 (2023)
Cellular senescence contributes importantly to aging and aging-related diseases, including idiopathic pulmonary fibrosis (IPF). Alveolar epithelial type II (ATII) cells are progenitors of alveolar epithelium, and ATII cell senescence is evident in IP
Externí odkaz:
https://doaj.org/article/6b040f7b3355402e8f456e3b845966cb
Autor:
Kenneth P. Hough, Miranda L. Curtiss, Trevor J. Blain, Rui-Ming Liu, Jennifer Trevor, Jessy S. Deshane, Victor J. Thannickal
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Asthma is an inflammatory disease of the airways that may result from exposure to allergens or other environmental irritants, resulting in bronchoconstriction, wheezing, and shortness of breath. The structural changes of the airways associated with a
Externí odkaz:
https://doaj.org/article/7ec7050af39f4fa4aba066295cbe8044
Autor:
Anand Singh, Bhargav Koduru, Cameron Carlisle, Hasina Akhter, Rui-Ming Liu, Katrin Schroder, Ralf P. Brandes, David M. Ojcius
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Chronic inflammation plays a key role in development of many liver diseases. Stimulation of Toll-like receptor 4 (TLR4) by bacterial lipopolysaccharide (LPS) initiates inflammation and promotes development of hepatocellular carcinoma and oth
Externí odkaz:
https://doaj.org/article/14803d8c07644567bd54da6829b932b4
Autor:
Wen Li, Rui Wang, Jie-yi Ma, Mian Wang, Jin Cui, Wei-bin Wu, Rui-ming Liu, Chun-xiang Zhang, Shen-ming Wang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 43, Iss 3, Pp 1152-1167 (2017)
Background/Aims: ALT1 is a novel long non-coding RNA derived from the alternatively spliced transcript of the deleted in lymphocytic leukemia 2 (DLEU2). To date, ALT1 biological roles in human vascular endothelial cells have not been reported. Method
Externí odkaz:
https://doaj.org/article/9431a286d07b4c94949ceaab75a6ebc4
Autor:
Xiao-feng Zhu, Zhen Shan, Jie-yi Ma, Mian Wang, Chun-xiang Zhang, Rui-ming Liu, Wei-bin Wu, Ya-wei Shi, Wen Li, Shen-ming Wang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 36, Iss 4, Pp 1359-1370 (2015)
Aims: To explore the expression of miR-24-3p in human arteries with arteriosclerosis obliterans (ASO) as well as the role of miR-24-3p in the pathogenesis of ASO. Methods: We used quantitative real-time PCR (qRT-PCR) and in situ hybridization to moni
Externí odkaz:
https://doaj.org/article/5de50306a761431d9e56a203e40e4009
Autor:
Ci-Qiu Yang, Wen Li, Song-Qi Li, Jie Li, Yu-Wen Li, Shu-Xin Kong, Rui-Ming Liu, Shen-Ming Wang, Wei-Ming Lv
Publikováno v:
Cellular Physiology and Biochemistry, Vol 34, Iss 2, Pp 266-276 (2014)
Objective: We investigated the molecular mechanism underlying the role of monocyte chemoattractant protein-1 (MCP-1) in the formation and development of human abdominal aortic aneurysm (AAA). Methods: We examined protein expression profiles using a p
Externí odkaz:
https://doaj.org/article/4cdf0c4a438b47cd95153ddd45fc7b7a
Autor:
Fu Jun Li, Ranu Surolia, Pooja Singh, Kevin G. Dsouza, Crystal T. Stephens, Zheng Wang, Rui-Ming Liu, Sejong Bae, Young-Il Kim, Mohammad Athar, Mark T. Dransfield, Veena B. Antony
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
The etiologies of chronic obstructive pulmonary disease (COPD) remain unclear. Cadmium (Cd) causes both pulmonary fibrosis and emphysema; however, the predictors for Cd exposure and the mechanisms by which Cd causes COPD remain unknown. We demonstrat
Publikováno v:
Marine Georesources & Geotechnology. 41:327-338
Autor:
Veena B. Antony, Victor J. Thannickal, Chunsun Jiang, Lu Cai, Jessy S. Deshane, Gang Liu, Rui-Ming Liu
Publikováno v:
The American Journal of Pathology
Increased apoptosis sensitivity of alveolar type 2 (ATII) cells and increased apoptosis resistance of (myo)fibroblasts, the apoptosis paradox, contributes to the pathogenesis of idiopathic pulmonary fibrosis (IPF). The mechanism underlying the apopto