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pro vyhledávání: '"Rui-hua XU"'
Akademický článek
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Diagnosis and prognosis prediction of gastric cancer by high-performance serum lipidome fingerprints
Autor:
Ze-Rong Cai, Wen Wang, Di Chen, Hao-Jie Chen, Yan Hu, Xiao-Jing Luo, Yi-Ting Wang, Yi-Qian Pan, Hai-Yu Mo, Shu-Yu Luo, Kun Liao, Zhao-Lei Zeng, Shan-Shan Li, Xin-Yuan Guan, Xin-Juan Fan, Hai-long Piao, Rui-Hua Xu, Huai-Qiang Ju
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3089-3112 (2024)
Abstract Early detection is warranted to improve prognosis of gastric cancer (GC) but remains challenging. Liquid biopsy combined with machine learning will provide new insights into diagnostic strategies of GC. Lipid metabolism reprogramming plays a
Externí odkaz:
https://doaj.org/article/d961b8da922348d18607888a9b8ccac9
Autor:
Dan-Yun Ruan, Xiao-Li Wei, Fu-Rong Liu, Xi-Chun Hu, Jian Zhang, Dong-Mei Ji, Ding-Zhi Huang, Yan-Qiu Zhao, Hong-Min Pan, Wang-Jun Liao, Kun-Yu Yang, Nong Xu, Xiao-Xiao Lu, Yu-Ling Chen, Wen Zhang, Hui Zhou, Hong-Yun Zhao, Rui-Hua Xu
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-12 (2024)
Abstract Background There is an unmet clinical need to enhance the response rate and safety of anti-PD-1/PD-L1-based cancer immunotherapy (IO). Herein, we presented the clinical study of IBI318 (LY3434172), a first-in-class bispecific antibody (bsAb)
Externí odkaz:
https://doaj.org/article/a9a7ec4c1b9647f89eb73df41a05bd37
Autor:
Haiyan Zhang, Xiaojing Luo, Wei Yang, Zhiying Wu, Zhicong Zhao, Xin Pei, Xue Zhang, Chonghao Chen, Josh Haipeng Lei, Qingxia Shi, Qi Zhao, Yanxing Chen, Wenwei Wu, Zhaolei Zeng, Huai-Qiang Ju, Miaozhen Qiu, Jun Liu, Bin Shen, Minshan Chen, Jianjun Chen, Chu-Xia Deng, Rui-Hua Xu, Jiajie Hou
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract RNA methylation is an important regulatory process to determine immune cell function but how it affects the anti-tumor activity of CD8 T cells is not fully understood. Here we show that the N 6-methyladenosine (m6A) RNA reader YTHDF2 is high
Externí odkaz:
https://doaj.org/article/36a9495c82934abdac94acffc6f6a1c2
Publikováno v:
Cell Rep Med
Rui-Hua Xu completed the REGOTORI trial that showed a novel combination regimen, regorafenib plus toripalimab, improved the efficacy and survival of refractory metastatic colorectal cancer, and found high-abundance Fusobacterium negatively predicted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1cd77648393dfe4b10fad08f9a5789c7
https://pubmed.ncbi.nlm.nih.gov/36090529
https://pubmed.ncbi.nlm.nih.gov/36090529
Autor:
Ying Jin, Run-Jie Huang, Wen-Long Guan, Zhi-Qiang Wang, Zong-Jiong Mai, Yu-Hong Li, Jian Xiao, Xing Zhang, Qi Zhao, Shi-Fu Chen, Ming Liu, Yan-Xia Shi, Feng Wang, Rui-Hua Xu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-11 (2024)
Abstract Patients carrying mutations in polymerase epsilon/polymerase delta have shown positive responses to immune checkpoint inhibitors. Yet, prospective trials exploring the efficacy in those with polymerase epsilon/polymerase delta mutations are
Externí odkaz:
https://doaj.org/article/e6f6d0c5d1ef434bbde38b71bbd7b039
Autor:
Qingjian Chen, Yu‐Hong Xu, Shiyang Kang, WuHao Lin, Linna Luo, Luping Yang, Qi‐Hua Zhang, Pan Yang, Jia‐Qian Huang, Xiaoni Zhang, Jing Zhang, Qi Zhao, Rui‐Hua Xu, Hui‐Yan Luo
Publikováno v:
MedComm, Vol 5, Iss 12, Pp n/a-n/a (2024)
Abstract Colorectal adenomas (CRAs) represent precancerous lesions that precede the development of colorectal cancer (CRC). Regular monitoring of CRAs can hinder the progression into carcinoma. To explore the utility of tissue DNA and circulating cel
Externí odkaz:
https://doaj.org/article/b77a1329a2ff43c484f365d79e441a66
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Shixiang Wang, Chen-Yi Wu, Ming-Ming He, Jia-Xin Yong, Yan-Xing Chen, Li-Mei Qian, Jin-Ling Zhang, Zhao-Lei Zeng, Rui-Hua Xu, Feng Wang, Qi Zhao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The clinical implications of extrachromosomal DNA (ecDNA) in cancer therapy remain largely elusive. Here, we present a comprehensive analysis of ecDNA amplification spectra and their association with clinical and molecular features in multip
Externí odkaz:
https://doaj.org/article/9b36599cda2349b884244b646a2a766b
Autor:
Feng‐Hua Wang, Xiao‐Tian Zhang, Lei Tang, Qi Wu, Mu‐Yan Cai, Yuan‐Fang Li, Xiu‐Juan Qu, Hong Qiu, Yu‐Jing Zhang, Jie‐Er Ying, Jun Zhang, Ling‐Yu Sun, Rong‐Bo Lin, Chang Wang, Hao Liu, Miao‐Zhen Qiu, Wen‐Long Guan, Sheng‐Xiang Rao, Jia‐Fu Ji, Yan Xin, Wei‐Qi Sheng, Hui‐Mian Xu, Zhi‐Wei Zhou, Ai‐Ping Zhou, Jing Jin, Xiang‐Lin Yuan, Feng Bi, Tian‐Shu Liu, Han Liang, Yan‐Qiao Zhang, Guo‐Xin Li, Jun Liang, Bao‐Rui Liu, Lin Shen, Jin Li, Rui‐Hua Xu
Publikováno v:
Cancer Communications, Vol 44, Iss 1, Pp 127-172 (2024)
Abstract The 2023 update of the Chinese Society of Clinical Oncology (CSCO) Clinical Guidelines for Gastric Cancer focuses on standardizing cancer diagnosis and treatment in China, reflecting the latest advancements in evidence‐based medicine, heal
Externí odkaz:
https://doaj.org/article/ddb71d41f751472a92fb64e883303e66