Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rui-Xiang Yuan"'
Publikováno v:
Bioorganicmedicinal chemistry letters. 76
A series of novel 1-(1-benzoylpiperidin-4-yl) methanamine derivatives were synthesized and evaluated for the serotonin reuptake inhibitory abilities and binding affinities to the 5-HT
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 76:129006
Autor:
Lian-Hua Song, Ke-Yu Jiang, Rui-Xiang Yuan, Xiao-Wen Chen, Yang-Li Qi, Hong Mou, Jian-Wei Wu, Jun-Wei Xu
A convenient and practical synthetic route was here developed for the preparation of the cis isomer of cariprazine (2), a dopamine D3-preferring D3-D2 receptor partial agonist for the treatment of schizophrenia. The key step is the concise preparatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37d3126563c0ee7b4852f8b011ace8a
Publikováno v:
Bioorganicmedicinal chemistry letters. 31
In this study, a series of trans-4-(2-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)ethyl)cyclohexan-1-amine derivatives as potential antipsychotics were synthesized and biologically evaluated to discover potential antipsychotics with good drug target s