Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Rui-Ping Xi"'
Autor:
Sven O. Göpel, Damilola Adingupu, Jue Wang, Elizaveta Semenova, Margareta Behrendt, Rasmus Jansson-Löfmark, Christine Ahlström, Ann-Cathrine Jönsson-Rylander, V. Sashi Gopaul, Russell Esterline, Li-Ming Gan, Rui-Ping Xiao
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background SGLT2 inhibitors, a T2DM medication to lower blood glucose, markedly improve cardiovascular outcomes but the underlying mechanism(s) are not fully understood. SGLT2i’s produce a unique metabolic pattern by lowering blood glucose
Externí odkaz:
https://doaj.org/article/e4b485641d78496b9714711ae24f8c10
Publikováno v:
BioResources. 15:6974-6988
Ionic liquids (ILs) are effective solvents for lignocellulose pretreatment. Enzymatic saccharification converts pretreated lignocelluloses into valuable products, and IL-tolerant cellulase improves the enzymatic efficiency and the reuse of ILs. In th
Autor:
Meng Fang, Hong-Kun Wu, Yumeng Pei, Yan Zhang, Xiangyu Gao, Yanyun He, Gengjia Chen, Fengxiang Lv, Peng Jiang, Yumei Li, Wenwen Li, Lin Wang, Jiafu Ji, Xinli Hu, Rui-Ping Xiao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-12 (2023)
Abstract Due to the essential role of cyclin D1 in regulating transition from G1 to S phase in cell cycle, aberrant cyclin D1 expression is a major oncogenic event in many types of cancers. In particular, the dysregulation of ubiquitination-dependent
Externí odkaz:
https://doaj.org/article/e360a05504074936985e799da34289a5
Autor:
Chun-Guang Guo, Rui Sun, Xiao Wang, Ye Yuan, Yan Xu, Shihan Li, Xueting Sun, Jue Wang, Xinli Hu, Tiannan Guo, Xiao-Wei Chen, Rui-Ping Xiao, Xiuqin Zhang
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101847- (2024)
Objective: Lipoprotein assembly and secretion in the small intestine are critical for dietary fat absorption. Surfeit locus protein 4 (SURF4) serves as a cargo receptor, facilitating the cellular transport of multiple proteins and mediating hepatic l
Externí odkaz:
https://doaj.org/article/f7bc8a151e4c4d15af6a05dfbc6f5ad1
Autor:
Jue Wang, Wen Zheng, Shuquan Zheng, Ye Yuan, Wei Wen, Weiyi Cui, Lifang Xue, Xueting Sun, Haibao Shang, Hongyan Zhang, Rui-Ping Xiao, Shan Gao, Xiuqin Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 68-77 (2023)
Angiopoietin-like protein 3 (ANGPTL3) is an important regulator of lipoproteins by inhibiting both lipoprotein and endothelial lipases. It has been intensively investigated as a drug target for the treatment of dyslipidemia. In the present study, a m
Externí odkaz:
https://doaj.org/article/d61838593eed4ab0953d2fb0db6b93ed
Autor:
Xiaohai Zhou, Chenyang Zhang, Xueying Wu, Xinli Hu, Yan Zhang, Xuelian Wang, Lixia Zheng, Peng Gao, Jianyong Du, Wen Zheng, Haibao Shang, Keping Hu, Zhengfan Jiang, Yu Nie, Shengshou Hu, Rui-Ping Xiao, Xiaojun Zhu, Jing-Wei Xiong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Dusp6, an ERK specific phosphatase, was identified as a regenerative repressor during zebrafish heart regeneration. Here, the authors show that Dusp6 deficiency improves post infarctional cardiac repair by predominantly attenuating neutrophil-mediate
Externí odkaz:
https://doaj.org/article/52019d9b29114e4d8bfd914f95194350
Autor:
Xiuqin Zhang, Dan Li, Rui Sun, Xinli Hu, Zhiqi Song, Xiaotian Ni, Hua Zhu, Tiannan Guo, Chuan Qin, Rui-Ping Xiao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/c6427e87603241588c590b9aa2ccbd11
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100497- (2021)
Summary: Exogenous overexpression of target genes in both general and specific cell types is important for mechanistic studies of gene function. Here, we provide a step-by-step protocol for cell culture, plasmid transfection in HEK293T, and adenovira
Externí odkaz:
https://doaj.org/article/b5ac9952c2d5447ca008073e0888c36f
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100496- (2021)
Summary: The AMP-activated protein kinase (AMPK) is a principal nutrient sensor and a master regulator of cellular energy homeostasis. Once activated, AMPK induces glucose uptake, which leads to a transient decrease in blood glucose level and can be
Externí odkaz:
https://doaj.org/article/0d757ec8403544699286e350eabffa0f
Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys
Autor:
Wen Zheng, Yuli Liu, Haibao Shang, Yan Zhang, Dongwei Ma, Ning Hou, Jue Wang, Xueting Sun, Ying Peng, Lin Pan, Zhilong Wang, Xinran Tang, Rui-Ping Xiao, Xiuqin Zhang
Publikováno v:
Diabetology & Metabolic Syndrome, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a global epidemic afflicting 20–30% in the general population. The animal model of NAFLD available at the present are less clinically relevant. In this study. We aimed to establish a
Externí odkaz:
https://doaj.org/article/ad5dd20963db45d08650576f2b8775d6