Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Rui-Ming Xu"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 12, Pp 1190-1199 (2023)
Abstract This study aimed to explore the role and mechanism of DYRK1a regulating ferroptosis of cardiomyocytes during myocardial ischemia–reperfusion injury (MIRI). H9c2 cells treated with oxygen–glucose deprivation/reoxygenation (OGD/R) were use
Externí odkaz:
https://doaj.org/article/fa8b18bede904723a1778599a25194bf
Autor:
Li-Heng Che, Jing-Wen Liu, Jian-Ping Huo, Rong Luo, Rui-Ming Xu, Cai He, Yu-Qing Li, Ai-Jun Zhou, Piao Huang, Yong-Yu Chen, Wen Ni, Yun-Xia Zhou, Yuan-Yuan Liu, Hui-Yan Li, Rong Zhou, Hui Mo, Jian-Ming Li
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-21 (2021)
Abstract Metastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC) patients. How to improve therapeutic options for patients with metastatic CRC is the core question for CRC treatment. However, the complexity and diversit
Externí odkaz:
https://doaj.org/article/47b12b6590204be68f27458c116c97ab
Autor:
Chaoyang Xiong, Zengqi Wen, Juan Yu, Jun Chen, Chao-Pei Liu, Xiaodong Zhang, Ping Chen, Rui-Ming Xu, Guohong Li
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-18 (2018)
Abstract Background H3.3 is an ancient and conserved H3 variant and plays essential roles in transcriptional regulation. HIRA complex, which is composed of HIRA, UBN1 or UBN2, and Cabin1, is a H3.3 specific chaperone complex. However, it still remain
Externí odkaz:
https://doaj.org/article/db45361008fa495f92d8ffb558920954
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181601 (2017)
Protein arginine methyltransferase 5 (PRMT5) plays critical roles in a wide variety of biological processes, including tumorigenesis. By screening a library of small chemical compounds, we identified eight compounds that selectively inhibit the PRMT5
Externí odkaz:
https://doaj.org/article/2291e2f5c2114d85b6c51266fea9e97d
Publikováno v:
eLife, Vol 5 (2016)
Externí odkaz:
https://doaj.org/article/5178f46736754da39f94c8b11e21651e
Publikováno v:
eLife, Vol 5 (2016)
Human cytomegalovirus (hCMV) immediate early 1 (IE1) protein associates with condensed chromatin of the host cell during mitosis. We have determined the structure of the chromatin-tethering domain (CTD) of IE1 bound to the nucleosome core particle, a
Externí odkaz:
https://doaj.org/article/d5ccb8aae2824d78a5f7299303ab4d35
Autor:
Ya-Nan Wang, Mao-Feng Liu, Wei-Zhen Hou, Rui-Ming Xu, Jie Gao, An-Qi Lu, Mei-Ping Xie, Lan Li, Jian-Jun Zhang, Ying Peng, Li-Li Ma, Xiao-Liang Wang, Jian-Gong Shi, Su-Juan Wang
Publikováno v:
Molecules, Vol 22, Iss 2, p 236 (2017)
Four new benzofuran-type stilbene glycosides and 14 known compounds including 8 benzofuran-type stilbenes and 6 flavonoids were isolated from the traditional Chinese medicine, Cortex Mori Radicis. The new compounds were identified as (9R)-moracin P 3
Externí odkaz:
https://doaj.org/article/2bd58e1a6f2c479e854ec7639121375f
Autor:
Ke Liu, Yahong Guo, Haiping Liu, Chuanbing Bian, Robert Lam, Yongsong Liu, Farrell Mackenzie, Luis Alejandro Rojas, Danny Reinberg, Mark T Bedford, Rui-Ming Xu, Jinrong Min
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30375 (2012)
SMN (Survival motor neuron protein) was characterized as a dimethyl-arginine binding protein over ten years ago. TDRD3 (Tudor domain-containing protein 3) and SPF30 (Splicing factor 30 kDa) were found to bind to various methyl-arginine proteins inclu
Externí odkaz:
https://doaj.org/article/6fccd819d46f45daa02ee5d99a6f918f
Publikováno v:
Genes & development, vol 36, iss 7-8
Chaperones influence histone conformation and intermolecular interaction in multiprotein complexes, and the structures obtained with full-length histones often provide more accurate and comprehensive views. Here, our structure of the Hat1–Hat2 acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2afa5d5c57ba57e384cda3625dd1a91
https://doi.org/10.1101/gad.349099.121
https://doi.org/10.1101/gad.349099.121
Autor:
Jing Zhang, Yan Zhang, Qinglong You, Chang Huang, Tiantian Zhang, Mingzhu Wang, Tianwei Zhang, Xiaocheng Yang, Jun Xiong, Yingfeng Li, Chao-Pei Liu, Zhuqiang Zhang, Rui-Ming Xu, Bing Zhu
Publikováno v:
Science. 375:1053-1058
Bivalent genes are ready for activation upon the arrival of developmental cues. Here, we report that BEND3 is a CpG island (CGI)–binding protein that is enriched at regulatory elements. The cocrystal structure of BEND3 in complex with its target DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243d4ce3a0a52b0ee1943c51f945d4c5
https://doi.org/10.1126/science.abm0730
https://doi.org/10.1126/science.abm0730