Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Rui Ogura"'
Autor:
Michiko Watanabe, Kouichi Yoshinari, Eri Yonekawa, Jun-ichi Takeshita, Yuki Shimizu, Takuomi Hosaka, Hirokazu Yamazaki, Ryota Shizu, Rui Ogura, Takamitsu Sasaki
Publikováno v:
The Journal of Toxicological Sciences. 46:167-176
Drug-induced liver injury (DILI) is one of the major causes for the discontinuation of drug development and withdrawal of drugs from the market. Since it is known that reactive metabolite formation and being substrates or inhibitors of cytochrome P45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3353ff92cdd8f8d182805d6b8373d7e8
https://doi.org/10.2131/jts.46.167
https://doi.org/10.2131/jts.46.167
Autor:
Yuki, Shimizu, Takamitsu, Sasaki, Eri, Yonekawa, Hirokazu, Yamazaki, Rui, Ogura, Michiko, Watanabe, Takuomi, Hosaka, Ryota, Shizu, Jun-Ichi, Takeshita, Kouichi, Yoshinari
Publikováno v:
The Journal of toxicological sciences. 46(4)
Drug-induced liver injury (DILI) is one of the major causes for the discontinuation of drug development and withdrawal of drugs from the market. Since it is known that reactive metabolite formation and being substrates or inhibitors of cytochrome P45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be7f276591a5e840c78b70f138e07b67
https://pubmed.ncbi.nlm.nih.gov/33814510
https://pubmed.ncbi.nlm.nih.gov/33814510
Autor:
Kouichi Yoshinari, Michiko Watanabe, Rui Ogura, Haruka Nakayama, Jun-ichi Takeshita, Ryota Shizu, Takamitsu Sasaki, Madoka Kushida, Takuomi Hosaka, Yuki Shimizu, Hitomi Oki, Yoko Kitsunai, Hitomi Saruhashi
Publikováno v:
Toxicology and applied pharmacology. 388
Repeated-dose toxicity (RDT) studies are one of the critical studies to assess chemical safety. There have been some studies attempting to predict RDT endpoints based on chemical substructures, but it remains very difficult to establish such a method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b68124bcbd0da75eda236aea9ff1fdf
https://pubmed.ncbi.nlm.nih.gov/31836524
https://pubmed.ncbi.nlm.nih.gov/31836524