Zobrazeno 1 - 10
of 382
pro vyhledávání: '"Rui Moreira"'
Autor:
Joana Gonçalves, Joana D. Amaral, Rita Capela, Maria de Jesus Perry, Cláudia Braga, Maria Manuela Gaspar, Fátima M. Piedade, Lubertus Bijlsma, Antoni Roig, Sandra N. Pinto, Rui Moreira, Pedro Florindo, Cecília M. P. Rodrigues
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Inducing necroptosis in cancer cells has emerged as an effective strategy to overcome drug resistance. However, while organic small molecules have been extensively studied for this purpose, metal-based compounds have received relatively litt
Externí odkaz:
https://doaj.org/article/cfb9a99efa384c4998ddab96fc03402d
Autor:
Rui Moreira, Augusta Silveira, Teresa Sequeira, Nuno Durão, Jessica Lourenço, Inês Cascais, Rita Maria Cabral, Tiago Taveira Gomes
Publikováno v:
Interactive Journal of Medical Research, Vol 13, p e35132 (2024)
BackgroundOral health is a determinant of overall well-being and quality of life. Individual behaviors, such as oral hygiene and dietary habits, play a central role in oral health. Motivation is a crucial factor in promoting behavior change, and gami
Externí odkaz:
https://doaj.org/article/3fbdb18ad5f1464aa4cd701db864ba25
Autor:
César Ricardo Coimbra de Matos, Eduarda Maria da Conceição Sério Pereira Beirão, Rafael Simões Neves, António José Assunção, Rui Moreira Marques
Publikováno v:
São Paulo Medical Journal, Vol 142, Iss 3 (2023)
ABSTRACT Neuroleptic malignant syndrome (NMS) is a neurologic emergency potentially fatal. This rare side effect is most commonly associated with first-generation antipsychotics and less frequently with atypical or second-generation antipsychotics. T
Externí odkaz:
https://doaj.org/article/d11cddca3a014663a5686c0207800141
Publikováno v:
Medical Sciences Forum, Vol 22, Iss 1, p 23 (2023)
We have developed a novel aptamer-based siRNA delivery system for HIV therapy. Apsi510 was obtained by chemical conjugation of an anti-HIV integrase aptamer and an siRNA sequence targeting the HIV-1 TAR/poly A regions to a dendron [2-((4-(2,5-dioxo-2
Externí odkaz:
https://doaj.org/article/7848a9c53e92434893dac9d724b48316
Autor:
Debora Inacio Leite, Stefany de Castro Bazan Moura, Maria da Conceição Avelino Dias, Carolina Catta Preta Costa, Gustavo Peixoto Machado, Luiz Claudio Ferreira Pimentel, Frederico Silva Castelo Branco, Rui Moreira, Monica Macedo Bastos, Nubia Boechat
Publikováno v:
Molecules, Vol 28, Iss 8, p 3342 (2023)
The human immunodeficiency virus (HIV) produces the pathologic basis of acquired immunodeficiency syndrome (AIDS). An increase in the viral load in the body leads to a decline in the number of T lymphocytes, compromising the patient’s immune system
Externí odkaz:
https://doaj.org/article/2842a872c8f14859b5c3843aef77c3e9
Autor:
Susana Rocha, Rita Félix, Maria João Valente, Andreia Bento-Silva, Rute Rebelo, Célia Gomes Amorim, Alberto da Nova Araújo, Rui Moreira, Alice Santos-Silva, Maria Conceição B. S. M. Montenegro
Publikováno v:
Membranes, Vol 13, Iss 1, p 89 (2023)
The use of polysulfone (PSU) hemodialysis (HD) membranes modified with bioactive compounds has gained relevance in chronic kidney disease (CKD) management. Compounds based on the 4-oxo-β-lactam scaffold have outstanding inhibitory ability and select
Externí odkaz:
https://doaj.org/article/8538716824b8481ab28f189b141197f1
Autor:
Natália Aniceto, Vanda Marques, Joana D. Amaral, Patrícia A. Serra, Rui Moreira, Cecília M. P. Rodrigues, Rita C. Guedes
Publikováno v:
Molecules, Vol 27, Iss 15, p 4718 (2022)
Necroptosis has emerged as an exciting target in oncological, inflammatory, neurodegenerative, and autoimmune diseases, in addition to acute ischemic injuries. It is known to play a role in innate immune response, as well as in antiviral cellular res
Externí odkaz:
https://doaj.org/article/1b84936adb6a4f47a3b9debc9b99c2d7
Autor:
Marta Barbosa, Cátia Gomes, Catarina Sequeira, Joana Gonçalves-Ribeiro, Carolina Campos Pina, Luís A. Carvalho, Rui Moreira, Sandra H. Vaz, Ana Rita Vaz, Dora Brites
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Reactive astrocytes in Amyotrophic Lateral Sclerosis (ALS) change their molecular expression pattern and release toxic factors that contribute to neurodegeneration and microglial activation. We and others identified a dysregulated inflammatory miRNA
Externí odkaz:
https://doaj.org/article/42771c50c3fa4e2396ce40ccf6654bad
Autor:
Aline Almeida da Silva, Antonia Maria da Silva Teixeira, Carla Magda Allan Santos Domingues, Rui Moreira Braz, Cibelle Mendes Cabral
Publikováno v:
Epidemiologia e Serviços de Saúde, Vol 30, Iss 1 (2021)
Resumo Objetivo Avaliar o Sistema de Vigilância em Imunizações considerando-se o módulo Registro do Vacinado, do Sistema de Informações do Programa Nacional de Imunizações, Brasil, 2017. Métodos Estudo descritivo, utilizando-se do Guidelines
Externí odkaz:
https://doaj.org/article/1a79b7a879d44123b9c71b2114cf1d75
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 7418-7423 (2018)
Externí odkaz:
https://doaj.org/article/b844fe88fcc54db08acace9c55b8fa1d