Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Rui M. Gil da-Costa"'
Autor:
Tiago Azevedo, Tiago Ferreira, Sheila I. Peña‐Corona, Hernán Cortes, Rita Silva‐Reis, Rui M. Gil da Costa, Ana I. Faustino‐Rocha, Paula A. Oliveira, Daniela Calina, Susana M. Cardoso, Dietrich Büsselberg, Gerardo Leyva‐Gómez, Javad Sharifi‐Rad, William C. Cho
Publikováno v:
Food Frontiers, Vol 5, Iss 6, Pp 2423-2466 (2024)
Abstract Angiogenesis, vital for tumor growth and metastasis, is a promising target in cancer therapy. Natural compounds offer potential as antiangiogenic agents with reduced toxicity. This review provides a comprehensive overview of natural product
Externí odkaz:
https://doaj.org/article/3c4897721da74225a5fa19306093b296
Autor:
Beatriz Medeiros-Fonseca, Ana I. Faustino-Rocha, Jéssica Silva, Mónica G. Silva, Maria João Pires, Maria João Neuparth, Helena Vala, Cármen Vasconcelos-Nóbrega, Maria I. Dias, Lillian Barros, Lio Gonçalves, Isabel Gaivão, Margarida M. S. M. Bastos, Luís Félix, Carlos Venâncio, Rui Medeiros, Rui M. Gil da Costa, Paula A. Oliveira
Publikováno v:
Exploration of Medicine, Vol 5, Iss 3, Pp 416-433 (2024)
Aim: Aloysia citrodora has a long history of traditional use in treating various ailments. This study evaluated the in vivo chemopreventive efficacy and systemic toxicity of an extract of A. citrodora in a transgenic mouse model of HPV16 (human papil
Externí odkaz:
https://doaj.org/article/9953ec61a2244bdd824c62f81a66f0cb
Autor:
Katia Regina Assunção Borges, Lais Araújo Souza Wolff, Marcos Antonio Custódio Neto da Silva, Allysson Kayron de Carvalho Silva, Carmem Duarte Lima Campos, Franscristhiany Silva Souza, Amanda Mara Teles, André Álvares Marques Vale, Henrique Pascoa, Eliana Martins Lima, Eduardo Martins de Sousa, Ana Clara Silva Nunes, Rui M. Gil da Costa, Ana Isabel Faustino-Rocha, Rafael Cardoso Carvalho, Maria do Desterro Soares Brandão Nascimento
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 3763-3793 (2024)
This study explores a nanoemulsion formulated with açaí seed oil, known for its rich fatty acid composition and diverse biological activities. This study aimed to characterise a nanoemulsion formulated with açaí seed oil and explore its cytotoxic
Externí odkaz:
https://doaj.org/article/47c69ffd8c5443bdbfcab944562aec66
Autor:
Rui M. Gil da Costa, Christine Levesque, Daniella Bianchi‐Frias, Payel Chatterjee, Hung‐Ming Lam, Carlos Santos, Ilsa M. Coleman, Pedro Ferreirinha, Manuel Vilanova, Nazaré Pinto da Cunha, Hugo Carvalho, Alexandra Moreira‐Pais, Ana Faustino‐Rocha, Tiago Neto, José Batista da Costa, Jonathan L. Wright, Rita Ferreira, Paula A. Oliveira, Joaquim Mendes, Margarida M. S. M. Bastos, Bruno Colaço, Carlos Lopes, Peter C. Black, Christopher J. Sweeney, Peter S. Nelson
Publikováno v:
Molecular Oncology, Vol 17, Iss 12, Pp 2709-2727 (2023)
Most patients with muscle‐invasive bladder cancer (MIBC) are not cured with platinum chemotherapy. Up‐regulation of nuclear factor kappa light‐chain enhancer of activated B cells (NF‐κB) is a major mechanism underlying chemoresistance, sugge
Externí odkaz:
https://doaj.org/article/c67189174a934005bc879e99ac388170
Autor:
Paula Alexandra Martins de-Oliveira, Ana I. Faustino-Rocha, Rui M. Gil da-Costa, Elisabete Nascimento Goncalves, Ana Margarida Calado, Catarina Jota Baptista, Adelina Gama, Fernanda Seixas
Publikováno v:
Open Veterinary Journal, Vol 13, Iss 9, Pp 1223-1227 (2023)
Background: Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues. Case Description: A 25-week-old female control FVB/n mouse in a 4-week toxicity study presented abdominal distension and poor
Externí odkaz:
https://doaj.org/article/100f91a96fbc432aafe7b7263239e965
Autor:
Fátima Badiche-El Hilali, Beatriz Medeiros-Fonseca, Jéssica Silva, Ana C. Silvestre-Ferreira, Maria João Pires, Rui M. Gil da Costa, Francisco Peixoto, Paula A. Oliveira, Daniel Valero
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 588 (2024)
Lemon is a fruit rich in antioxidant properties and has several health benefits, namely the reduction of skin edema and anticarcinogenic properties, which are due to its high content of bioactive compounds. Melatonin can improve and preserve the prop
Externí odkaz:
https://doaj.org/article/c56a2e0f90f84f3c8e575604bfdcc727
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/6b8a1d1e80394428bfbaa4d06606af8b
Autor:
Beatriz Medeiros-Fonseca, Ana I. Faustino-Rocha, Rui Medeiros, Paula A. Oliveira, Rui M. Gil da Costa
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Papillomaviruses are small viruses able to cause disease not only in mammalians, but also in birds and reptiles. In recent years, a rising number of papillomaviruses have been identified in dogs and cats, totaling 24 canine papillomavirus (CPV) and s
Externí odkaz:
https://doaj.org/article/c961bcb0a2b94f92a8d1bc0f5f783dfb
Autor:
Jucileide Mota, Alice Marques Moreira Lima, Jhessica I. S. Gomes, Marcelo Souza de Andrade, Haissa O. Brito, Melaine M. A. Lawall Silva, Ana I. Faustino-Rocha, Paula A. Oliveira, Fernanda F. Lopes, Rui M. Gil da Costa
Publikováno v:
Diagnostics, Vol 13, Iss 21, p 3357 (2023)
Klotho proteins, αKlotho, βKlotho, and γKlotho, exert tumor-suppressive activities via the fibroblast growth factor receptors and multiple cell-signaling pathways. There is a growing interest in Klotho proteins as potential diagnostic and prognost
Externí odkaz:
https://doaj.org/article/7fcd0ac271bb4f3995e88a8e2b05e74a
Autor:
Sara Peixoto da Silva, Joana M.O. Santos, Maria Paula Costa e Silva, Rui M. Gil da Costa, Rui Medeiros
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 11, Iss 3, Pp 619-635 (2020)
Abstract Cancer cachexia is a multifactorial syndrome characterized by a progressive loss of skeletal muscle mass, along with adipose tissue wasting, systemic inflammation and other metabolic abnormalities leading to functional impairment. Cancer cac
Externí odkaz:
https://doaj.org/article/fe7468a3354640848d579d55889da9c4