Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Rui Lan Zhang"'
Autor:
Lei Wang, Michael Chopp, Alexandra Szalad, Zhongwu Liu, Mei Lu, Li Zhang, Jing Zhang, Rui Lan Zhang, Dan Morris, Zheng Gang Zhang
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 3, Pp 546-555 (2012)
Peripheral neuropathy is one of the most common complications of diabetes mellitus. Using a mouse model of diabetic peripheral neuropathy, we tested the hypothesis that thymosin β4 (Tβ4) ameliorates diabetes‐induced neurovascular dysfunction in t
Externí odkaz:
https://doaj.org/article/b8a8d61c374e491bb2863d756fa9af17
Autor:
Lei Wang, Michael Chopp, Alexandra Szalad, XueRong Lu, LongFei Jia, Mei Lu, Rui Lan Zhang, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159665 (2016)
We previously demonstrated that treatment of diabetic peripheral neuropathy with the short (4 hours) half-life phosphodiesterase 5 (PDE5) inhibitor, sildenafil, improved functional outcome in diabetic db/db mice. To further examine the effect of PDE5
Externí odkaz:
https://doaj.org/article/558239baa2e74ff68429bc11867d2cac
Autor:
Rui Lan Zhang, Michael Chopp, Cynthia Roberts, Xianshuang Liu, Min Wei, Siamak P Nejad-Davarani, Xinli Wang, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113972 (2014)
The unique cellular and vascular architecture of the adult ventricular-subventricular zone (V/SVZ) neurogenic niche plays an important role in regulating neural stem cell function. However, the in vivo identification of neural stem cells and their re
Externí odkaz:
https://doaj.org/article/697a7a08747a4be0b8d699e4ecf5347d
Autor:
Rui Lan Zhang, Michael Chopp, Cynthia Roberts, Min Wei, Xinli Wang, Xianshuang Liu, Mei Lu, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e48141 (2012)
Adult neural stem cells give rise to neurons, oligodendrocytes and astrocytes. Aging reduces neural stem cells. Using an inducible nestin-CreER(T2)/R26R-yellow fluorescent protein (YFP) mouse, we investigated the effect of Sildenafil, a phosphodieste
Externí odkaz:
https://doaj.org/article/3f82dce5980241ac9a079d44c2d3c957
Autor:
Xian Shuang Liu, Michael Chopp, Rui Lan Zhang, Tang Tao, Xin Li Wang, Haifa Kassis, Ann Hozeska-Solgot, Li Zhang, Charles Chen, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23461 (2011)
The Notch signaling pathway regulates adult neurogenesis under physiological and pathophysiological conditions. MicroRNAs are small non-coding RNA molecules that regulate gene expression. The present study investigated the effect of miR-124a on the N
Externí odkaz:
https://doaj.org/article/5718a7552ef34490abe6472890dbb599
Autor:
Li Zhang, Michael Chopp, Rui Lan Zhang, Lei Wang, Jing Zhang, Ying Wang, Yier Toh, Manoranjan Santra, Mei Lu, Zheng Gang Zhang
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11016 (2010)
Erythropoietin (EPO), a hematopoietic cytokine, enhances neurogenesis and angiogenesis during stroke recovery. In the present study, we examined the effect of EPO on oligodendrogenesis in a rat model of embolic focal cerebral ischemia.Recombinant hum
Externí odkaz:
https://doaj.org/article/5497e2433a8b48fd8478ca961657b264
Autor:
Rui Lan Zhang, Chao Li, Xianshuang S Liu, Zheng Gang Zhang, Albert M. Levin, Baoyan Fan, Michael Chopp
Publikováno v:
Stroke. 52
Background: Adult neurogenesis facilitates brain remodeling after stroke. Exosomes derived from neural stem cells (NSCs) promote ischemic neurovascular remodeling including angiogenesis and axonal outgrowth, potentially by transferring their cargo pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88944e495e285a5ddea659289dd401d4
https://doi.org/10.1161/str.52.suppl_1.p751
https://doi.org/10.1161/str.52.suppl_1.p751
Autor:
Michael Chopp, Zheng Gang Zhang, Haifa Kassis, Xiao Ming Zhang, Xin Li Wang, Rui Lan Zhang, Bao Yan Fan, Yi Zhang, Wan Long Pan, Xian Shuang Liu
Publikováno v:
Molecular Neurobiology. 54:227-237
Stroke induces new myelinating oligodendrocytes that are involved in ischemic brain repair. Molecular mechanisms that regulate oligodendrogenesis have not been fully investigated. MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079228b9358bcf1146405649aa4c36aa
https://doi.org/10.1007/s12035-015-9655-7
https://doi.org/10.1007/s12035-015-9655-7
Publikováno v:
Nature Protocols. 10:539-547
Animal models of focal cerebral ischemia are well accepted for investigating the pathogenesis and potential treatment strategies for human stroke. Occlusion of the middle cerebral artery (MCA) with an endovascular filament is a widely used model to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8602961b01e8e16f71c8b28c26bfb2e6
https://doi.org/10.1038/nprot.2015.036
https://doi.org/10.1038/nprot.2015.036
Publikováno v:
Applied Mechanics and Materials. 711:61-64
The output characteristics of solar cell that researched as the target is analysed at different temperatures and light intensity .Combining with the equivalent circuit of solar cell, mathematical model is established .The system is simulated through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dba439649af5f787bcf14ac4921802
https://doi.org/10.4028/www.scientific.net/amm.711.61
https://doi.org/10.4028/www.scientific.net/amm.711.61